Genetic polymorphisms in the vascular endothelial growth factor gene and breast cancer risk. The Austrian ¡°tumor of breast tissue: incidence, genetics, and environmental risk factors?study
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- 作者：Uwe Langsenlehner ; Gerald Wolf ; Tanja Langsenlehner ; Armin Gerger ; G¨¹nter Hofmann ; Heimo Clar ; Thomas C. Wascher ; Bernhard Paulweber ; Hellmut Samonigg and Peter Krippl ; et al.
- 关键词：Breast cancer ; Vegf polymorphisms ; Haplotypes ; Genetics ; Epidemiology ; Vegf plasma levels
- 刊名：Breast Cancer Research and Treatment
- 出版年：2008
- 出版时间：May, 2008
- 年：2008
- 卷：109
- 期：2
- 页码：297-304
- 全文大小：181.8 KB
文摘
Purpose Vascular endothelial growth factor (VEGF) is a key regulator of tumor-induced angiogenesis and is required for growth of tumors. We tested the hypothesis that VEGF gene polymorphisms may be associated with breast cancer.