Nine months aerobic fitness induced changes on blood lipids and lipoproteins in untrained subjects versus controls

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• 作者：Susanne Ring-Dimitriou ; Serge P. von Duvillard ; Bernhard Paulweber ; Monika Stadlmann ; Linda M. LeMura ; Kayla Peak and Erich Mueller
• 关键词：Aerobic fitness ; Running ; Blood lipids ; Lipoproteins
• 刊名：European Journal of Applied Physiology
• 出版年：2007
• 出版时间：February, 2007
• 年：2007
• 卷：99
• 期：3
• 页码：291-299
• 全文大小：409 KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Human Physiology
  Occupational and Industrial Medicine
  Sports Medicine
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1439-6327

文摘

Regular endurance exercise has favorable effects on cardiovascular risk factors. However, the impact of an exercise-induced change in aerobic fitness on blood lipids is often inconsistent. The purpose of this study was to investigate the effect of nine consecutive months of training on aerobic fitness and blood lipids in untrained adults. Thirty subjects 35–55 years of age (wt: 73.1 ± 13.6 kg, height 171.1 ± 9.0 cm, %body fat 24.6 ± 6.3%, 14 males and 16 females) were randomly assigned to an exercise (EG) (N = 20) and control (CG) (N = 10) group. All subjects completed an incremental treadmill test, anthropometric measurements, and venous blood sample collection before and after the 9 months of exercise. Participants in the exercise group were supervised and adjusted for improvements in running performance, whereas no change was administered for the control group. One-way and multivariate ANOVA was conducted to determine significant differences in means for time and group in selected variables [body mass, % body fat, BMI; VO_2peak, km/h at 2.0 (v-LA2) and 4.0 (v-LA4) mmol l?1 blood lactate (LA) concentration, km/h of the last load (v-max); TC, LDL-C, HDL-C, TG, Apo B, Apo A-1, and Lp (a)]. Correlation coefficients and multivariate regression analysis was used to determine the association between aerobic fitness and blood lipids. The exercise group improved significantly (P < 0.0001) in VO_2peak, v-LA2, v-LA4, v-max and exhibited a significant decrease in Apo B (P < 0.04) compared to the control group (NS). In 9 months, E achieved 24% increase in VO_2peak and 18% reduction in Apo B, denoting the impact of cardiovascular fitness on cardiovascular risk.