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Use of FDG-PET to detect a chronic odontogenic infection as a possible source of the brain abscess
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  • 作者:Jun Sato ; Takeshi Kuroshima ; Mayumi Wada ; Akira Satoh ; Shiro Watanabe…
  • 关键词:FDG ; PET ; Brain abscess ; Odontogenic infection ; Chronic infection
  • 刊名:Odontology
  • 出版年:2016
  • 出版时间:May 2016
  • 年:2016
  • 卷:104
  • 期:2
  • 页码:239-243
  • 全文大小:715 KB
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  • 作者单位:Jun Sato (1)
    Takeshi Kuroshima (1)
    Mayumi Wada (1)
    Akira Satoh (1)
    Shiro Watanabe (2)
    Shozo Okamoto (2)
    Tohru Shiga (2)
    Nagara Tamaki (2)
    Yoshimasa Kitagawa (1)

    1. Division of Oral Pathobiological Science, Department of Oral Diagnosis and Medicine, Hokkaido University Graduate School of Dental Medicine, North 13, West 7, Kita-ku, Sapporo, 060-8586, Japan
    2. Department of Nuclear Medicine, Graduate School of Medicine, Hokkaido University, North 15, West 7, Kita-ku, Sapporo, Hokkaido, 060-8638, Japan
  • 刊物类别:Medicine
  • 刊物主题:Dentistry
  • 出版者:Springer Japan
  • ISSN:1618-1255
文摘
This study describes the use of 18F-fluoro-2-deoxyglucose positron emission tomography (FDG-PET) to detect a chronic odontogenic infection as the possible origin of a brain abscess (BA). A 74-year-old man with esophageal carcinoma was referred to our department to determine the origin of a BA in his oral cavity. He had no acute odontogenic infections. The BA was drained, and bacteria of the Staphylococcus milleri group were detected. Whole body FDG-PET revealed that the only sites of definite uptake of FDG were the esophageal carcinoma and the left upper maxillary region (SUVmax: 4.5). These findings suggested that the BA may have originated from a chronic periodontal infection. Six teeth with progressive chronic periodontal disease were extracted to remove the possible source of BA. These findings excluded the possibility of direct spread of bacteria from the odontogenic infectious lesion to the intracranial cavity. After extraction, there was no relapse of BA.

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