Diarrhées chroniques infectieuses et dysimmunitaires

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• 作者：V. Polin (1)
  H. Hagège (1)
  
• 关键词：Immunodépression ; Infection par le VIH ; Déficit immunitaire primitif ; Giardiase ; Pullulation microbienne intestinale ; Maladie de Whipple ; Immune deficiency ; HIV infectious ; Primary immunodeficiency disorders ; Giardiasis ; Intestinal bacterial overgrowth ; Whipple disease
• 刊名：C?lon & Rectum
• 出版年：2010
• 出版时间：May 2010
• 年：2010
• 卷：4
• 期：2
• 页码：108-114
• 全文大小：156KB
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• 作者单位：V. Polin (1)
  H. Hagège (1)
  
  1. Service d’hépatogastroentérologie, CHI de Créteil, 40, avenue de Verdun, F-94000, Créteil, France
  

文摘

Clinical background is an essential data to achieve diagnosis of chronic diarrhea from infectious or immune dysfunction etiology. In HIV patients when the immune deficiency is important, diarrhea can be related to opportunistic infection. This diarrhea may be due to parasitic or bacterial infection. In primary immunodeficiency disorders, villous atrophy may also explain chronic diarrhea. Giardiasis, responsible for diarrhea and malabsorption, should always be looked for, because immune competent patients are not spared. Some specific clinical data (surgery history, achlorhydria, diabetes, immune deficiency, etc.) may be relevant to diagnose gut microbial pullulation. Whipple disease, although rare, should be kept in mind as treatment is easy and prognosis without treatment is very poor.