In vivo response to polypropylene following implantation in animal models: a review of biocompatibility

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• 作者：Michelle Kelly ; Katherine Macdougall…
• 关键词：Biocompatibility ; Host response ; Mesh ; Pelvic organ prolapse ; Polypropylene ; Stress urinary incontinence
• 刊名：International Urogynecology Journal
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：28
• 期：2
• 页码：171-180
• 全文大小：406KB
• 刊物主题：Gynecology; Urology;
• 出版者：Springer London
• ISSN：1433-3023
• 卷排序：28

文摘

Introduction and hypothesisPolypropylene is a material that is commonly used to treat pelvic floor conditions such as pelvic organ prolapse (POP) and stress urinary incontinence (SUI). Owing to the nature of complications experienced by some patients implanted with either incontinence or prolapse meshes, the biocompatibility of polypropylene has recently been questioned. This literature review considers the in vivo response to polypropylene following implantation in animal models. The specific areas explored in this review are material selection, impact of anatomical location, and the structure, weight and size of polypropylene mesh types.