New reactions of benzocaine

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• 作者：Yu. A. Azev ; O. S. Ermakova ; V. S. Berseneva…
• 关键词：aromatic amines ; benzocaine ; quinolones ; 2 ; 3 ; substituted quinolines
• 刊名：Russian Journal of General Chemistry
• 出版年：2016
• 出版时间：November 2016
• 年：2016
• 卷：86
• 期：11
• 页码：2442-2445
• 全文大小：
• 刊物类别：Chemistry and Materials Science
• 刊物主题：Chemistry/Food Science, general;
• 出版者：Pleiades Publishing
• ISSN：1608-3350
• 卷排序：86

文摘

Reaction of benzocaine with indane-1,3-dione-2-carbaldehyde afforded the corresponding azomethine. Ethoxymethylenemalonate reacted with benzocaine to form ethyl 4-{[2-(ethoxycarbonyl)-4-methoxy-3-oxobuten-1-yl]amino}benzoate, which was converted to the corresponding quinolone when heated to 185–190°C. Reactions of benzocaine with aliphatic aldehydes furnished 2,3-alkyl-substituted quinolines.