Bradyarrythmias in the obstructive sleep apnea sundrome: a dangerous complication or defense mechanism?

详细信息    查看全文

• 作者：L. S. Korostovtseva ; S. O. Kravchenko…
• 关键词：sleep ; apnea ; heart rhythm and conductance disorders ; mammals ; autonomic regulation
• 刊名：Journal of Evolutionary Biochemistry and Physiology
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：52
• 期：4
• 页码：305-312
• 全文大小：120 KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Evolutionary Biology
  Biochemistry
  Animal Physiology
  Russian Library of Science
  
• 出版者：MAIK Nauka/Interperiodica distributed exclusively by Springer Science+Business Media LLC.
• ISSN：1608-3202
• 卷排序：52

文摘

Sleep is characterized by cycling and consecutive alternation of different phases and stages, each of which features intrinsic changes in autonomic regulation with heart rate oscillations; this may cause heart rhythm disorders, especially in the presence of comorbidities. This review addresses the issues of interrelationship between cardiac conduction disorders and obstructive sleep apnea. It is shown that some mechanisms of bradyarrythmia emergence (first of all, features of autonomic regulation with increases in parasympathetic tone) under respiratory arrest during sleep are also inherent to human divers as well as aquatic or para-aquatic mammals that have to hold their breath when diving or staying under water for a long time. These mechanisms may fulfill the defense function.