Acute rheumatic fever outbreak in southern central European country

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• 作者：Urška Kočevar ; Nataša Toplak ; Blaž Kosmač ; Luka Kopač…
• 关键词：Acute rheumatic fever ; Central Europe ; Heart valve disease ; Arthritis
• 刊名：European Journal of Pediatrics
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：176
• 期：1
• 页码：23-29
• 全文大小：
• 刊物主题：Pediatrics;
• 出版者：Springer Berlin Heidelberg
• ISSN：1432-1076
• 卷排序：176

文摘

A decline in the incidence of acute rheumatic fever (ARF) in developed countries over the past century can be attributed to the improved public hygiene and to widespread use of antibiotics. ARF seemed to be a rare disease in southern central European country, Slovenia, up to 2010 when we noticed an increase in the number of patients with ARF. In order to assess the current incidence of ARF, we performed a retrospective study of all patients with ARF treated at the University Children’s Hospital Ljubljana from January 2008 until the end of December 2014. In a period of 7 years, 19 patients with ARF were identified. The estimated annual incidence of ARF during the study period was 1.25 cases per 100,000 children. Carditis was present in all patients, arthritis in 37 % and Sydenham chorea in 32 %.