Effects of the Thiazolidinedione Medications on Micro- and Macrovascular Complications in Patients with Diabetes¡ªUpdate 2008

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• 作者：Anand Rohatgi and Darren K. McGuire
• 关键词：Thiazolidinedione ; Pioglitazone ; Rosiglitazone ; Diabetes ; Microvascular disease ; Macrovascular disease ; Myocardial infarction ; Heart failure
• 刊名：Cardiovascular Drugs and Therapy
• 出版年：2008
• 出版时间：June, 2008
• 年：2008
• 卷：22
• 期：3
• 页码：233-240
• 全文大小：172.4 KB

文摘

Introduction The thiazolidinedione (TZD) drugs, including pioglitazone (Actos?) and rosiglitazone (Avandia?), are commonly prescribed in patients with type 2 diabetes mellitus (T2DM), largely due to their favorable effects on hyperglycemia, insulin sensitivity, and cardiometabolic profile. However, the data are sparse assessing the effects of TZDs on micro- and macrovascular disease risk.