Full-genome sequencing of a Hungarian canine G3P[3] Rotavirus A strain reveals high genetic relatedness with a historic Italian human strain
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- 作者：H. Papp ; E. Mihalov-Kovács ; R. Dóró ; S. Marton ; S. L. Farkas…
- 关键词：Zoonosis ; Semiconductor sequencing ; Phylogenetic analysis ; Genotype constellation
- 刊名：Virus Genes
- 出版年：2015
- 出版时间：April 2015
- 年：2015
- 卷：50
- 期：2
- 页码：310-315
- 全文大小：1,031 KB
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- 刊物主题：Biomedicine
Medical Microbiology
Virology
Plant Sciences - 出版者：Springer Netherlands
- ISSN：1572-994X
文摘
A canine Rotavirus A strain was identified in the fecal specimen of a young dog during 2012 in Hungary. The strain RVA/Dog-wt/HUN/135/2012/G3P[3] shared complete genotype constellation (G3-P[3]-I3-R3-C3-M3-A15-N2-T3-E3-H6) and high genome sequence similarity (nt, 98.8?%) with a historic human strain, RVA/Human-tc/ITA/PA260-97/1997/G3P[3]. This study provides evidence for the canine origin of the unusual NSP1 genotype, A15, and reinforces the hypothesis of direct interspecies transmission of canine rotaviruses to humans.
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