The Minnesota Green Tea Trial (MGTT), a randomized controlled trial of the efficacy of green tea extract on biomarkers of breast cancer risk: study rationale, design, methods, and participant characteristics

详细信息    查看全文

• 作者：Hamed Samavat ; Allison M. Dostal ; Renwei Wang ; Sarah Bedell&#8230
• 关键词：Breast cancer ; Green tea ; Mammographic density ; Postmenopausal women ; Sex hormones
• 刊名：Cancer Causes & Control
• 出版年：2015
• 出版时间：October 2015
• 年：2015
• 卷：26
• 期：10
• 页码：1405-1419
• 全文大小：482 KB
• 参考文献：1.Siegel R, Ma J, Zou Z, Jemal A (2014) Cancer statistics, 2014. CA Cancer J Clin 64:9鈥?9CrossRef PubMed
  2.Kushi LH, Doyle C, McCullough M, Rock CL, Demark-Wahnefried W, Bandera EV, Gapstur S, Patel AV, Andrews K, Gansler T et al (2012) American Cancer Society Guidelines on nutrition and physical activity for cancer prevention: reducing the risk of cancer with healthy food choices and physical activity. CA Cancer J Clin 62:30鈥?7CrossRef PubMed
  3.Thomson CA (2012) Diet and breast cancer: understanding risks and benefits. Nutr Clin Pract 27:636鈥?50CrossRef PubMed
  4.Yang CS, Wang X, Lu G, Picinich SC (2009) Cancer prevention by tea: animal studies, molecular mechanisms and human relevance. Nat Rev Cancer 9:429鈥?39CrossRef PubMed Central PubMed
  5.Wang ZY, Huang MT, Lou YR, Xie JG, Reuhl KR, Newmark HL, Ho CT, Yang CS, Conney AH (1994) Inhibitory effects of black tea, green tea, decaffeinated black tea, and decaffeinated green tea on ultraviolet B light-induced skin carcinogenesis in 7,12-dimethylbenz[a]anthracene-initiated SKH-1 mice. Cancer Res 54:3428鈥?435PubMed
  6.Sartippour MR, Shao ZM, Heber D, Beatty P, Zhang L, Liu C, Ellis L, Liu W, Go VL, Brooks MN (2002) Green tea inhibits vascular endothelial growth factor (VEGF) induction in human breast cancer cells. J Nutr 132:2307鈥?311PubMed
  7.Ogunleye AA, Xue F, Michels KB (2010) Green tea consumption and breast cancer risk or recurrence: a meta-analysis. Breast Cancer Res Treat 119:477鈥?84CrossRef PubMed
  8.Yang CS, Wang H, Li GX, Yang Z, Guan F, Jin H (2011) Cancer prevention by tea: evidence from laboratory studies. Pharmacol Res 64:113鈥?22CrossRef PubMed
  9.Wu AH, Ursin G, Koh WP, Wang R, Yuan JM, Khoo KS, Yu MC (2008) Green tea, soy, and mammographic density in Singapore Chinese women. Cancer Epidemiol Biomarkers Prev 17:3358鈥?365CrossRef PubMed Central PubMed
  10.Wu AH, Arakawa K, Stanczyk FZ, Van Den Berg D, Koh WP, Yu MC (2005) Tea and circulating estrogen levels in postmenopausal Chinese women in Singapore. Carcinogenesis 26:976鈥?80CrossRef PubMed
  11.Fuhrman BJ, Pfeiffer RM, Wu AH, Xu X, Keefer LK, Veenstra TD, Ziegler RG (2013) Green tea intake is associated with urinary estrogen profiles in Japanese-American women. Nutr J 12:25CrossRef PubMed Central PubMed
  12.Li M, He Z, Ermakova S, Zheng D, Tang F, Cho YY, Zhu F, Ma WY, Sham Y, Rogozin EA et al (2007) Direct inhibition of insulin-like growth factor-I receptor kinase activity by (鈥?-epigallocatechin-3-gallate regulates cell transformation. Cancer Epidemiol Biomarkers Prev 16:598鈥?05CrossRef PubMed
  13.Yang CS, Maliakal P, Meng X (2002) Inhibition of carcinogenesis by tea. Annu Rev Pharmacol Toxicol 42:25鈥?4CrossRef PubMed
  14.Klaunig JE, Kamendulis LM (2004) The role of oxidative stress in carcinogenesis. Annu Rev Pharmacol Toxicol 44:239鈥?67CrossRef PubMed
  15.Donovan JL, DeVane CL, Chavin KD, Oates JC, Njoku C, Patrick KS, Fiorini RN, Markowitz JS (2005) Oral administration of a decaffeinated green tea (Camellia sinensis) extract did not alter urinary 8-epi-prostaglandin F(2 alpha), a biomarker for in vivo lipid peroxidation. J Pharm Pharmacol 57:1365鈥?369CrossRef PubMed
  16.Qian G, Xue K, Tang L, Wang F, Song X, Chyu MC, Pence BC, Shen CL, Wang JS (2012) Mitigation of oxidative damage by green tea polyphenols and Tai Chi exercise in postmenopausal women with osteopenia. PLoS ONE 7:e48090CrossRef PubMed Central PubMed
  17.Lachman HM, Papolos DF, Saito T, Yu YM, Szumlanski CL, Weinshilboum RM (1996) Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders. Pharmacogenetics 6:243鈥?50CrossRef PubMed
  18.Dawling S, Roodi N, Mernaugh RL, Wang X, Parl FF (2001) Catechol-O-methyltransferase (COMT)-mediated metabolism of catechol estrogens: comparison of wild-type and variant COMT isoforms. Cancer Res 61:6716鈥?722PubMed
  19.Inoue-Choi M, Yuan JM, Yang CS, Van Den Berg DJ, Lee MJ, Gao YT, Yu MC (2010) Genetic association between the COMT genotype and urinary levels of tea polyphenols and their metabolites among daily green tea drinkers. Int J Mol Epidemiol Genet 1:114鈥?23PubMed Central PubMed
  20.Guldberg HC, Marsden CA (1975) Catechol-O-methyl transferase: pharmacological aspects and physiological role. Pharmacol Rev 27:135鈥?06PubMed
  21.Wu AH, Tseng CC, Van Den Berg D, Yu MC (2003) Tea intake, COMT genotype, and breast cancer in Asian-American women. Cancer Res 63:7526鈥?529PubMed
  22.ACR (2003) Breast imaging reporting and data system atlas (BI-RADS庐 Atlas)-mammography, 4th edn. American College of Radiology, Reston, VA, pp 179鈥?80
  23.Hilditch JR, Lewis J, Peter A, van Maris B, Ross A, Franssen E, Guyatt GH, Norton PG, Dunn E (1996) A menopause-specific quality of life questionnaire: development and psychometric properties. Maturitas 24:161鈥?75CrossRef PubMed
  24.Lewis JE, Hilditch JR, Wong CJ (2005) Further psychometric property development of the Menopause-Specific Quality of Life questionnaire and development of a modified version. MENQOL-Intervention questionnaire. Maturitas 50:209鈥?21CrossRef PubMed
  25.Bhagwat S, Haytowitz DB, Holden JM (2014) USDA Database for the flavonoid content of selected foods, release 3.1. U.S. Department of Agriculture, Agricultural Research Service. Nutrient Data Laboratory Home Page: http://鈥媤ww.鈥媋rs.鈥媢sda.鈥媑ov/鈥媙utrientdata/鈥媐lav . Accessed 13 Dec 2014
  26.Ursin G, Astrahan MA, Salane M, Parisky YR, Pearce JG, Daniels JR, Pike MC, Spicer DV (1998) The detection of changes in mammographic densities. Cancer Epidemiol Biomarkers Prev 7:43鈥?7PubMed
  27.Ursin G, Ma H, Wu AH, Bernstein L, Salane M, Parisky YR, Astrahan M, Siozon CC, Pike MC (2003) Mammographic density and breast cancer in three ethnic groups. Cancer Epidemiol Biomarkers Prev 12:332鈥?38PubMed
  28.Salameh WA, Redor-Goldman MM, Clarke NJ, Reitz RE, Caulfield MP (2010) Validation of a total testosterone assay using high-turbulence liquid chromatography tandem mass spectrometry: total and free testosterone reference ranges. Steroids 75:169鈥?75CrossRef PubMed
  29.Xu X, Veenstra TD, Fox SD, Roman JM, Issaq HJ, Falk R, Saavedra JE, Keefer LK, Ziegler RG (2005) Measuring fifteen endogenous estrogens simultaneously in human urine by high-performance liquid chromatography-mass spectrometry. Anal Chem 77:6646鈥?654CrossRef PubMed
  30.Morrow JD, Chen Y, Brame CJ, Yang J, Sanchez SC, Xu J, Zackert WE, Awad JA, Roberts LJ (1999) The isoprostanes: unique prostaglandin-like products of free-radical-initiated lipid peroxidation. Drug Metab Rev 31:117鈥?39CrossRef PubMed
  31.Morrow JD (2000) The isoprostanes: their quantification as an index of oxidant stress status in vivo. Drug Metab Rev 32:377鈥?85CrossRef PubMed
  32.Morrow JD, Roberts LJ (2002) Mass spectrometric quantification of F2-isoprostanes as indicators of oxidant stress. Methods Mol Biol 186:57鈥?6PubMed
  33.Gross M, Steffes M, Jacobs DR, Yu X, Lewis L, Lewis CE, Loria CM (2005) Plasma F2-isoprostanes and coronary artery calcification: the CARDIA Study. Clin Chem 51:125鈥?31CrossRef PubMed
  34.Lee MJ, Prabhu S, Meng X, Li C, Yang CS (2000) An improved method for the determination of green and black tea polyphenols in biomatrices by high-performance liquid chromatography with coulometric array detection. Anal Biochem 279:164鈥?69CrossRef PubMed
  35.Li C, Lee MJ, Sheng S, Meng X, Prabhu S, Winnik B, Huang B, Chung JY, Yan S, Ho CT et al (2000) Structural identification of two metabolites of catechins and their kinetics in human urine and blood after tea ingestion. Chem Res Toxicol 13:177鈥?84CrossRef PubMed
  36.Slot C (1965) Plasma creatinine determination. A new and specific Jaffe reaction method. Scand J Clin Lab Invest 17:381鈥?87CrossRef PubMed
  37.Hong CC, Thompson HJ, Jiang C, Hammond GL, Tritchler D, Yaffe M, Boyd NF (2003) Val158Met Polymorphism in catechol-O-methyltransferase gene associated with risk factors for breast cancer. Cancer Epidemiol Biomarkers Prev 12:838鈥?47PubMed
  38.Wu AH, Spicer D, Stanczyk FZ, Tseng CC, Yang CS, Pike MC (2012) Effect of 2-month controlled green tea intervention on lipoprotein cholesterol, glucose, and hormone levels in healthy postmenopausal women. Cancer Prev Res (Phila) 5:393鈥?02CrossRef
  39.Crew KD, Brown P, Greenlee H, Bevers TB, Arun B, Hudis C, McArthur HL, Chang J, Rimawi M, Vornik L et al (2012) Phase IB randomized, double-blinded, placebo-controlled, dose escalation study of polyphenon E in women with hormone receptor-negative breast cancer. Cancer Prev Res (Phila) 5:1144鈥?154CrossRef
  40.Chow HH, Cai Y, Alberts DS, Hakim I, Dorr R, Shahi F, Crowell JA, Yang CS, Hara Y (2001) Phase I pharmacokinetic study of tea polyphenols following single-dose administration of epigallocatechin gallate and polyphenon E. Cancer Epidemiol Biomarkers Prev 10:53鈥?8PubMed
  41.Chow HH, Cai Y, Hakim IA, Crowell JA, Shahi F, Brooks CA, Dorr RT, Hara Y, Alberts DS (2003) Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals. Clin Cancer Res 9:3312鈥?319PubMed
  42.Dostal AM, Samavat H, Bedell S, Torkelson C, Wang R, Swenson K, Le C, Wu AH, Ursin G, Yuan JM et al (2015) The safety of green tea extract supplementation in postmenopausal women at risk for breast cancer: results of the Minnesota Green Tea Trial. Food Chem Toxicol 83:26鈥?5CrossRef PubMed
  43.Neveu V, Perez-Jim茅nez J, Vos F, Crespy V, du Chaffaut L, Mennen L, Knox C, Eisner R, Cruz J, Wishart D et al (2010) Phenol-explorer: an online comprehensive database on polyphenol contents in foods. Database (Oxford) 2010, bap024
  
• 作者单位：Hamed Samavat (1)
  Allison M. Dostal (1)
  Renwei Wang (2)
  Sarah Bedell (1)
  Tim H. Emory (3)
  Giske Ursin (4) (5) (6)
  Carolyn J. Torkelson (7)
  Myron D. Gross (8)
  Chap T. Le (10) (9)
  Mimi C. Yu (6)
  Chung S. Yang (11)
  Douglas Yee (10) (12) (13)
  Anna H. Wu (6)
  Jian-Min Yuan (14) (2)
  Mindy S. Kurzer (1)
  
  1. Department of Food Science and Nutrition, University of Minnesota, St Paul, MN, USA
  2. Division of Cancer Control and Population Sciences, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA
  3. Department of Radiology, Center for Magnetic Resonance Research, University of Minnesota Medical School, Minneapolis, MN, USA
  4. Cancer Registry of Norway, Oslo, Norway
  5. Department of Nutrition, University of Oslo, Oslo, Norway
  6. Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
  7. Department of Family Medicine and Community Health, University of Minnesota Medical School, Minneapolis, MN, USA
  8. Department of Laboratory Medicine and Pathology, University of Minnesota Medical School, Minneapolis, MN, USA
  10. Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA
  9. Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, USA
  11. Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ, USA
  12. Department of Medicine, University of Minnesota, Minneapolis, MN, USA
  13. Department of Pharmacology, University of Minnesota, Minneapolis, MN, USA
  14. Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Oncology
  Cancer Research
  Public Health
  Epidemiology
  Hematology
  
• 出版者：Springer Netherlands
• ISSN：1573-7225

文摘

Purpose The Minnesota Green Tea Trial (MGTT) was a randomized, placebo-controlled, double-blinded trial investigating the effect of daily green tea extract consumption for 12 months on biomarkers of breast cancer risk.