Modified thresholds for fibrosis risk scores in nonalcoholic fatty liver disease are necessary in the obese

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• 作者：Geraldine J. Ooi ; Paul R. Burton ; Lisa Doyle ; John M. Wentworth…
• 关键词：Fibrosis risk scores ; NAFLD fibrosis score ; FIB ; 4 ; BARD ; APRI ; Forn score ; Nonalcoholic fatty liver disease ; Obesity ; Sensitivity and specificity
• 刊名：Obesity Surgery
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：27
• 期：1
• 页码：115-125
• 全文大小：
• 刊物主题：Surgery;
• 出版者：Springer US
• ISSN：1708-0428
• 卷排序：27

文摘

BackgroundObesity and its related comorbidities are significant risk factors for nonalcoholic fatty liver disease (NAFLD). Liver fibrosis is the major determinant of long-term outcomes in NAFLD. A non-invasive tool that accurately identifies obese patients at elevated risk of liver fibrosis would be of significant value. Fibrosis risk scores in patients with NAFLD have been proposed but have not been validated in obese populations. We aimed to validate established simple fibrosis scores in bariatric surgical patients.