Strong selection for behavioural resilience in Australian stock working dogs identified by selective sweep analysis

详细信息    查看全文

• 作者：Elizabeth R Arnott ; Lincoln Peek ; Jonathan B Early…
• 关键词：Kelpie ; Behaviour ; Selective sweep
• 刊名：Canine Genetics and Epidemiology
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：2
• 期：1
• 全文大小：1116KB
• 参考文献：1.Vonholdt BM, Pollinger JP, Lohmueller KE, Han E, Parker HG, Quignon P, et al. Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication. Nature. 2010;464(7290):898鈥?02. doi:nature08837 [pii]10.1038/nature08837.CrossRef PubMed Central PubMed
  2.Vaysse A, Ratnakumar A, Derrien T, Axelsson E, Rosengren Pielberg G, Sigurdsson S, et al. Identification of genomic regions associated with phenotypic variation between dog breeds using selection mapping. PLoS Genet. 2011;7(10):e1002316. doi:10.1371/journal.pgen.1002316PGENETICS-D-11-00264 [pii].CrossRef PubMed Central PubMed
  3.Boyko AR, Quignon P, Li L, Schoenebeck JJ, Degenhardt JD, Lohmueller KE, et al. A simple genetic architecture underlies morphological variation in dogs. PLoS Biol. 2010;8(8):e1000451. doi:10.1371/journal.pbio.1000451.CrossRef PubMed Central PubMed
  4.Quilez J, Short AD, Martinez V, Kennedy LJ, Ollier W, Sanchez A, et al. A selective sweep of >8聽Mb on chromosome 26 in the Boxer genome. BMC Genomics. 2011;12:339. doi:10.1186/1471-2164-12-339.CrossRef PubMed Central PubMed
  5.Bannasch D, Young A, Myers J, Truve K, Dickinson P, Gregg J, et al. Localization of canine brachycephaly using an across breed mapping approach. PLoS One. 2010;5(3):e9632. doi:10.1371/journal.pone.0009632.CrossRef PubMed Central PubMed
  6.Pollinger JP, Bustamante CD, Fledel-Alon A, Schmutz S, Gray MM, Wayne RK. Selective sweep mapping of genes with large phenotypic effects. Genome Res. 2005;15(12):1809鈥?9. doi:10.1101/gr.4374505.CrossRef PubMed Central PubMed
  7.Goddard ME, Beilharz RG. Genetics of traits which determine the suitability of dogs as guide-dogs for the blind. Appl Anim Ethol. 1983;9(3鈥?):299鈥?15.CrossRef
  8.The_Working_Kelpie_Council_of_Australia. Origin of the Kelpie. 2014. http://鈥媤ww.鈥媤kc.鈥媜rg.鈥媋u/鈥婣bout-Kelpies/鈥婳rigin-of-the-Kelpie.鈥媝hp . Accessed 30/09/2014.
  9.Arnott ER, Early JB, Wade CM, McGreevy PD. Environmental Factors Associated with Success Rates of Australian Stock Herding Dogs. PloS One. 2014;9(8). doi:ARTN e104457DOI 10.1371/journal.pone.0104457.
  10.Arnott ER, Early JB, Wade CM, McGreevy PD. Estimating the economic value of Australian stock herding dogs. Anim Welf. 2014;23(2):189鈥?7. doi:10.7120/09627286.23.2.189.CrossRef
  11.Early JB, Arnott ER, Wade CM, McGreevy PD. Manual muster: a critical analysis of the use of common terms in Australian working dog manuals. J Vet Behav. 2014;9(6):370鈥?.CrossRef
  12.van Rooy D, Arnott ER, Early JB, McGreevy PD, Wade CM. Holding back the genes: limitations of research into canine behavioural genetics. Canine Genet Epidemiol. 2014;1:1鈥?. doi:10.1186/2052-6687-1-7.CrossRef
  13.Australian_National_Kennel_Council. Australian Kelpie extended breed standard. 2015. http://鈥媋nkc.鈥媜rg.鈥媋u/鈥媘edia/鈥媝df/鈥?355763443209307鈥?4_鈥媎0d9014f-a85b-407a-8dc0-d2010a9293e0.鈥媝df . Accessed 18/03/2015.
  14.Sabeti PC, Reich DE, Higgins JM, Levine HZ, Richter DJ, Schaffner SF, et al. Detecting recent positive selection in the human genome from haplotype structure. Nature. 2002;419(6909):832鈥?. doi:10.1038/nature01140.CrossRef PubMed
  15.de Simoni Gouveia JJ, da Silva MV, Paiva SR, de Oliveira SM. Identification of selection signatures in livestock species. Genet Mol Biol. 2014;37(2):330鈥?2.CrossRef PubMed Central PubMed
  16.Felsenstein J. How Can We infer geography and history from gene-frequencies. J Theor Biol. 1982;96(1):9鈥?0. doi:10.1016/0022-5193(82)90152-7.CrossRef PubMed
  17.Lindblad-Toh K, Wade CM, Mikkelsen TS, Karlsson EK, Jaffe DB, Kamal M, et al. Genome sequence, comparative analysis and haplotype structure of the domestic dog. Nature. 2005;438(7069):803鈥?9. doi:10.1038/nature04338.CrossRef PubMed
  18.Hoeppner MP, Lundquist A, Pirun M, Meadows JRS, Zamani N, Johnson J, et al. An Improved Canine Genome and a Comprehensive Catalogue of Coding Genes and Non-Coding Transcripts. PloS One. 2014;9(3). doi:ARTN e91172DOI10.1371/journal.pone.0091172.
  19.Candille SI, Kaelin CB, Cattanach BM, Yu B, Thompson DA, Nix MA, et al. A -defensin mutation causes black coat color in domestic dogs. Science. 2007;318(5855):1418鈥?3. doi:10.1126/science.1147880.CrossRef PubMed Central PubMed
  20.Dreger DL, Parker HG, Ostrander EA, Schmutz SM. Identification of a mutation that is associated with the saddle Tan and black-and-Tan phenotypes in basset hounds and Pembroke welsh corgis. J Hered. 2013;104(3):399鈥?06. doi:10.1093/jhered/est012.CrossRef PubMed
  21.Dreger DL, Schmutz SM. A SINE insertion causes the black-and-Tan and saddle Tan phenotypes in domestic dogs. J Hered. 2011;102:S11鈥?. doi:10.1093/jhered/esr042.CrossRef PubMed
  22.Shearman JR, Cook RW, McCowan C, Fletcher JL, Taylor RM, Wilton AN. Mapping cerebellar abiotrophy in Australian Kelpies. Anim Genet. 2011;42(6):675鈥?. doi:10.1111/j.1365-2052.2011.02199.x.CrossRef PubMed
  23.Inoue N, Nakao H, Migishima R, Hino T, Matsui M, Hayashi F, et al. Requirement of the immediate early gene vesl-1S/homer-1a for fear memory formation. Mol Brain. 2009;2:7. doi:10.1186/1756-6606-2-7.CrossRef PubMed Central PubMed
  24.Klugmann M, Szumlinski KK. Targeting Homer genes using adeno-associated viral vector: lessons learned from behavioural and neurochemical studies. Behav Pharmacol. 2008;19(5鈥?):485鈥?00. doi:10.1097/FBP.0b013e32830c369f.CrossRef PubMed
  25.Szumlinski KK, Lominac KD, Kleschen MJ, Oleson EB, Dehoff MH, Schwarz MK, et al. Behavioral and neurochemical phenotyping of Homer1 mutant mice: possible relevance to schizophrenia. Genes Brain Behav. 2005;4(5):273鈥?8. doi:10.1111/j.1601-183X.2005.00120.x.CrossRef PubMed
  26.Singh I, Tucker LA, Gendall P, Rutherfurd-Markwick KJ, Cline J, Thomas DG. Age, breed, sex distribution and nutrition of a population of working farm dogs in New Zealand: results of a cross-sectional study of members of the New Zealand sheep dog trial association. N Z Vet J. 2011;59(3):133鈥?. doi:10.1080/00480169.2011.567967.CrossRef PubMed
  27.Lu B, Zhang Q, Wang H, Wang Y, Nakayama M, Ren D. Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex. Neuron. 2010;68(3):488鈥?9. doi:10.1016/j.neuron.2010.09.014.CrossRef PubMed Central PubMed
  28.Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D, et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet. 2007;81(3):559鈥?5. doi:10.1086/519795.CrossRef PubMed Central PubMed
  29.Blake JA, Bult CJ, Eppig JT, Kadin JA, Richardson JE. The Mouse Genome Database: integration of and access to knowledge about the laboratory mouse. Nucleic Acids Res. 2014;42(Database issue):D810鈥?. doi:10.1093/nar/gkt1225.CrossRef PubMed Central PubMed
  
• 作者单位：Elizabeth R Arnott (1)
  Lincoln Peek (1)
  Jonathan B Early (1)
  Annie Y H Pan (1)
  Bianca Haase (1)
  Tracy Chew (1)
  Paul D McGreevy (1)
  Claire M Wade (1)
  
  1. Faculty of Veterinary Science, University of Sydney, Camperdown, NSW, 2006, Australia
  
• 刊物类别：Gene Function; Veterinary Medicine;
• 刊物主题：Gene Function; Veterinary Medicine;
• 出版者：BioMed Central
• ISSN：2052-6687

文摘

Background Working dog handlers and breeders have strong opinions on characteristics that are desirable in the breeds that they use to handle stock. Most of these characteristics are related to conformation or behaviour. This study explored whether the genetics underlying desirable working behaviour traits might be identified by selective sweep analysis; a method that identifies long regions of strong homozygosity combined with allelic divergence from a comparison group. For this analysis, we compared genomic haplotype architecture in two breeds derived from common founder stock but subjected to divergent selective pressures. The breeds studied were the Australian Kelpie, which is registered with the Australian National Kennel Council, and the Australian Working Kelpie, which is registered with the Working Kelpie Council.