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Frequent down-regulation and deletion of KLF6 in primary hepatocellular carcinoma
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  • 作者:Shaoping Wang (1)
    Lili Kang (2)
    Xiaoping Chen (3)
    Hejun Zhou (4)
  • 关键词:tumor suppressor gene ; Kruppel ; like factor 6 ; gene expression ; cell proliferation ; hepatocellular carcinoma
  • 刊名:Journal of Huazhong University of Science and Technology [Medical Sciences]
  • 出版年:2010
  • 出版时间:August 2010
  • 年:2010
  • 卷:30
  • 期:4
  • 页码:470-476
  • 全文大小:499KB
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    3. Ng IO, Srivastava G, Chung LP, / et al. Overexpression and point mutations of p53 tumor suppressor gene in hepatocellular carcinomas in Hong Kong Chinese people. Cancer, 1994,74(1):30-7 CrossRef
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    12. Kremer-Tal S, Reeves HL, Narla G, / et al. Frequent inactivation of the tumor suppressor Kruppel-like factor 6 (KLF6) in hepatocellular carcinoma. Hepatology, 2004, 40(5):1047-052 CrossRef
    13. Kremer-Tal S, Narla G, Chen YB, / et al. Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation. J Hepatol, 2007,46(4):645-54 CrossRef
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    21. Bureau C, Péron JM, Bouisson M, / et al. Expression of the transcription factor Klf6 in cirrhosis, macronodules, and hepatocellular carcinoma. J Gastroenterol Hepatol, 2008,23(1):78-6 CrossRef
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  • 作者单位:Shaoping Wang (1)
    Lili Kang (2)
    Xiaoping Chen (3)
    Hejun Zhou (4)

    1. Department of Hepatobiliary Surgery, Futian People’s Hospital, Shenzhen, 518033, China
    2. School of Medicine, Shaoxing University, Shaoxing, 312000, China
    3. Center of Hepatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China
    4. Department of Gastroenterology, Xiangya Second Hospital, Central South University, Changsha, 410011, China
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