Repeated sessions of transcranial direct current stimulation evaluation on fatigue and daytime sleepiness in Parkinson’s disease

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• 作者：Bijan Forogh ; Maryam Rafiei ; Amin Arbabi ; Mohammad Reza Motamed…
• 关键词：Transcranial direct current stimulation ; Parkinson’s disease ; Fatigue ; Daytime sleepiness
• 刊名：Neurological Sciences
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：38
• 期：2
• 页码：249-254
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Neurology; Neuroradiology; Neurosurgery; Psychiatry;
• 出版者：Springer Milan
• ISSN：1590-3478
• 卷排序：38

文摘

Parkinson is a common and disabling disease that affects patient’s and career’s quality of life. Unfortunately, medications, such as dopaminergic and sedative-hypnotic drugs, as an effective treatment have unwilling side effects. Recently, Transcranial Direct Current Stimulation (tDCS) in conjunction with medication becomes popular as a complementary safe treatment and several studies have proved its effectiveness on controlling motor and specially non-motor aspects of Parkinson’s disease. In this randomized double-blind parallel study, 23 patients with Parkinson’s disease divided into two groups of real tDCS plus occupational therapy and sham tDCS plus occupational therapy and the effects of therapeutic sessions (eight sessions tDCS with 0.06 mA/cm2 current, 20 min on dorsolateral prefrontal cortex) were evaluated on fatigue and daytime sleepiness just after therapeutic course and in 3-month follow-up. tDCS had a significant effect on fatigue and no effect on daytime sleepiness reduction in patients with Parkinson’s disease. tDCS is an effective and safe complementary treatment on fatigue reduction in Parkinson’s disease.