Nucleic acid detection in the diagnosis and prevention of schistosomiasis
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- 作者：Ping He ; Lan-gui Song ; Hui Xie ; Jin-yi Liang…
- 关键词：Schistosoma japonicum ; S. mansoni ; S. haematobium ; Diagnosis ; Nucleic acid detection
- 刊名：Infectious Diseases of Poverty
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：5
- 期：1
- 全文大小：553 KB
- 刊物主题：Infectious Diseases; Tropical Medicine;
- 出版者：BioMed Central
- ISSN：2049-9957
文摘
Schistosomiasis is an important zoonotic parasitic disease that causes serious harms to humans and animals. Surveillance and diagnosis play key roles in schistosomiasis control, however, current techniques for surveillance and diagnosis of the disease have limitations. As genome data for parasites are increasing, novel techniques for detection incorporating nucleotide sequences are receiving widespread attention. These sensitive, specific, and rapid detection methods are particularly important in the diagnosis of low-grade and early infections, and may prove to have clinical significance. This paper reviews the progress of nucleic acid detection in the diagnosis and prevention of schistosomiasis, including such aspects as the selection of target genes, and development and application of nucleic acid detection methods.