Substance use, mental illness, and familial conflict non-negotiation among HIV-positive African-Americans: latent class regression and a new syndemic framework

详细信息    查看全文

• 作者：Allysha C. Robinson ; Amy R. Knowlton ; Andrea C. Gielen…
• 关键词：HIV ; Injection drug use ; Viral suppression ; Health disparities ; Syndemic theory ; African ; Americans ; Health services research
• 刊名：Journal of Behavioral Medicine
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：39
• 期：1
• 页码：1-12
• 全文大小：625 KB
• 参考文献：Ahn, J., McCombs, J. S., Jung, C., Croudace, T. J., McDonnell, D., Ascher-Svanum, H., et al. (2008). Classifying patients by antipsychotic adherence patterns using latent class analysis: characteristics of nonadherent groups in the California Medicaid (Medi-Cal) program. Value in Health, 11, 48–56.PubMed CrossRef
  Akaike, H. (1973). Information theory and an extension of the maximum likelihood principle. Budapest, Hungary: In Second International Symposium on Information Theory.
  Bastard, M., Koita, F. M., Laniece, I., Taverne, B., Desclaux, A., Ecochard, R., et al. (2011). Revisiting long-term adherence to HAART in Senegal using latent class analysis. Journal of Acquired Immune Deficiency Syndrome, 57, 55–61.CrossRef
  Bennett, D. A. (2001). How can I deal with missing data in my study? Australian and New Zealand Journal of Public Health, 25, 464–469.PubMed CrossRef
  Blank, M. B. (2014). Homelessness, mental illness, substance abuse, and HIV: An insidious syndemic. HIV/AIDS Research & Treatment Open Journal, 1, e001–e004.
  Blashill, A. J., Bedoya, C. A., Mayer, K. H., O’Cleirigh, C., Pinkston, M. M., Remmert, J. E., et al. (2014). Psychosocial syndemics are additively associated with worse ART adherence in HIV-infected individuals. AIDS and Behavior, 19, 981–986.CrossRef
  Brinkley-Rubinstein, L., & Craven, K. (2014). A latent class analysis of stigmatizing attitudes and knowledge of HIV risk among youth in South Africa. PLoS ONE, 9, e89915.PubMed PubMedCentral CrossRef
  Buseh, A. G., & Stevens, P. E. (2008). Constrained but not determined by stigma: Resistance by African-American women living with HIV. Women and Health, 44, 1–18.CrossRef
  Centers for Disease Control and Prevention [CDC]. (2012). HIV in the United States: The stages of care, 2012. Retrieved 17 Sept 2014, from http://​ww w.cdc.gov/nchhstp/newsroom/docs/2012/Stages-of-Care FactSheet-508.pdf.
  Collins, L. M., & Lanza, S. T. (2010). Latent class and latent transition analysis: With applications in the social, behavioral, and health sciences. New York, NY: Wiley.
  Fremont, A., Young, A., Chinman, M., Pantoja, P., Morton, S. C., Koegel, P., et al. (2007). Differences in HIV care between patients with and without severe mental illness. Psychiatric Services, 58, 681–688.PubMed CrossRef
  Freudenberg, N., Fahs, M., Galea, S., & Greenberg, A. (2006). The impact of New York city’s 1975 fiscal crisis on the tuberculosis, HIV, and homicide syndemic. American Journal of Public Health, 96, 424–434.PubMed PubMedCentral CrossRef
  Gielen, A. C., McDonnell, K. A., O’Campo, P. J., & Burke, J. G. (2005). Suicide risk and mental health indicators: Do they differ by abuse and HIV status? Women’s Health Issues, 15, 89–95.PubMed CrossRef
  González-Guarda, R. M., McCabe, B. E., Florom-Smith, A., Cianelli, R., & Peragallo, N. (2011). Substance abuse, violence, HIV, and depression an underlying syndemic factor among latinas. Nursing Research, 60, 182–189.PubMed PubMedCentral CrossRef
  González-Guarda, R. M., Ortega, J., Vasquez, E. P., & De Santis, J. (2010). La mancha negra: Substance abuse, violence, and sexual risks among Hispanic males. Western Journal of Nursing Research, 32, 128–148.PubMed PubMedCentral CrossRef
  Gullette, D. L., Wright, P. B., Booth, B. M., & Stewart, K. E. (2010). Stages of change, decisional balance, and self-efficacy in condom use among rural African-American stimulant users. Journal of Associated Nurses AIDS Care, 20, 428–441.CrossRef
  Halkitis, P. N., Kupprat, S. A., Hampton, M. B., Perez-Figueroa, R., Kingdon, M., Eddy, J. A., & Ompad, D. C. (2012). Evidence for a syndemic in aging HIV-positive gay, bisexual, and other MSM: Implications for a holistic approach to prevention and healthcare. Natural Resource Modeling, 36, 1–21.
  Halkitis, P. N., Moeller, R. W., Siconolfi, D. E., Storholm, E. D., Solomon, T. M., & Bub, K. L. (2013). Measurement model exploring a syndemic in emerging adult gay and bisexual men. AIDS and Behavior, 17, 662–673.PubMed PubMedCentral CrossRef
  Havlik, R. J., Brennan, M., & Karpiak, S. E. (2011). Comorbidities and depression in older adults with HIV. Sexual Health, 8, 551–559.PubMed CrossRef
  Horner, P., & Nassiri, R. (2013). Social cultural stressors in dominican republic HIV/AIDS prevention and treatment. Journal of AIDS & Clinical Research, 4, 1–6.
  Illangasekare, S., Burke, J., Chander, G., & Gielen, A. (2013). The syndemic effects of intimate partner violence, HIV/AIDS, and substance abuse on depression among low-income urban women. Journal of Urban Health, 90, 934–937.PubMed PubMedCentral CrossRef
  Johnson, W. D., Diaz, R. M., Flanders, W. D., Goodman, M., Hill, A. N., Holtgrave, D., et al. (2008). Behavioral interventions to reduce risk for sexual transmission of HIV among men who have sex with men. Cochrane Database of Systematic Reviews, 3, CD001230.
  Jones, D. J., Beach, S. R., Forehand, R., & Foster, S. E. (2003). Self-reported health in HIV-positive African-American women: The role of family stress and depressive symptoms. Journal of Behavioral Medicine, 26, 577–599.PubMed CrossRef
  Kaaya, S., Eustache, E., Lapidos-Salaiz, I., Musisi, S., Psaros, C., & Wissow, L., (2013). Grand challenges: Improving HIV treatment outcomes by integrating interventions for co-morbid mental illness. PL0S Medicine, 10(5), e1001447.
  Keiser, O., Spycher, B., Rauch, A., Calmy, A., Cavassini, M., Glass, T. R., et al. (2012). Outcomes of antiretroviral therapy in the swiss HIV cohort study: Latent class analysis. AIDS & Behavior, 16, 245–255.
  Knowlton, A. R., Yang, C., Bohnert, A., Wissow, L., Chander, G., & Arnsten, J. A. (2011). Main partner factors associated with worse adherence to ART among women in Baltimore, Maryland: A preliminary study. AIDS Care, 23(9), 1102–1110.CrossRef
  Konda, K. A., Celentano, D. D., Kegeles, S., Coates, T. J., Caceres, C. F., & NIMH Collaborative HIV/STD Prevention Trial Group. (2011). Latent class analysis of sexual risk patterns among esquineros (street corner men) a group of heterosexually identified, socially marginalized men in Urban Coastal Peru. AIDS & Behavior, 15, 862–868.
  Latkin, C. A., Forman, V., Knowlton, A., & Sherman, S. (2002). Norms, social networks, and HIV-related behaviors among urban disadvantaged drug users. Social Science and Medicine, 56, 465–476.CrossRef
  Li, L., Ji, G., Ding, Y., Tian, J., & Lee, A. (2012). Perceived burden in adherence of antiretroviral treatment in rural China. AIDS Care, 24, 502–508.PubMed PubMedCentral
  MacCallum, R. C., Zhang, S., Preacher, K. J., & Rucker, D. D. (2002). On the practice of dichotomization of quantitative variables. Psychological Methods, 7, 19–40.PubMed CrossRef
  Marcus, R. (2014). Women’s discourse on the homeless experience: It’s about love and loss. Retrieved 9 June 2015 from http://​digitalcommons.​uconn.​edu
  McDaid, L. M., & Hart, G. (2010). Sexual risk behaviour for transmission of HIV in men who have sex with men: recent findings and potential interventions. Current Opinion in HIV & AIDS, 5, 311–315.CrossRef
  McNutt, L., Wu, C., Xue, X., & Hafner, J. P. (2003). Estimating the relative risk in cohort studies and clinical trials of common outcomes. American Journal of Epidemiology, 157, 940–943.PubMed CrossRef
  Mendenhall, E. (2013). Syndemic suffering: Social distress, depression, and diabetes among mexican immigrant women. Walnut Creek, CA: Left Coast Press.
  Metzl, J. M., & Hansen, H. (2014). Structural competency: Theorizing a new medical engagement with stigma and inequality. Social Science and Medicine, 103, 126–133.PubMed PubMedCentral CrossRef
  Meyer, J. P., Springer, S. A., & Altice, F. L. (2011). Substance abuse, violence, and HIV in women: A literature review of the syndemic. Journal of Women’s Health, 20, 991–1006.PubMed PubMedCentral CrossRef
  Milstein, B. (2001). Introduction to the syndemics prevention network. Retrieved 14 Sept 2014 from http://​www.​cdc.​gov/​syndemics/​
  Minze, L. C., McDonald, R., Rosentraub, E. L., & Jouriles, E. N. (2010). Making sense of family conflict: Intimate partner violence and preschoolers’ externalizing problems. Journal of Family Psychology, 24, 5–11.PubMed CrossRef
  Mitrani, V. B., McCabe, B. E., Burns, M. J., & Feaster, D. J. (2012). Family mechanisms of structural ecosystems therapy for HIV-seropositive women in drug recovery. Health Psychology, 31, 591–600.PubMed CrossRef
  Mizuno, Y., Purcell, D. W., Knowlton, A. R., Wilkinson, J. D. Gourevitch, M. N., & Knight, K. R. (2014). Syndemic vulnerability, sexual and injection risk behaviors, and HIV continuum of care outcomes in HIV-positive injection drug users. AIDS & Behavior. doi:10.​1007/​s10461-014-0890-0
  Muthén, L. K., & Muthén, B. O. (2011). Mplus user’s guide (7th ed.). Los Angeles, CA: Muthén & Muthén.
  Nicholas, P. K., Willard, S., Thompson, C., Dawson-Rose, C., Corless, I. B., Wantland, D. J., et al. (2014). Engagement with care, substance use, and adherence to therapy in HIV/AIDS. AIDS Research & Treatment, 2014, 1–7.CrossRef
  Noor, S. W. B., Ross, M. W., Lai, D., & Risser, J. M. (2014). Use of latent class analysis approach to describe drug and sexual HIV risk patterns among injection drug users in Houston, Texas. AIDS and Behavior, 18, S276–S283.CrossRef
  Ostrach, B., & Singer, M. (2012). At special risk: Biopolitical vulnerability and HIV syndemics among women. Health Sociology Review, 21, 258–271.CrossRef
  Prejean, J., Song, R., Hernandez, A., Ziebell, R., Green, T., Walker, F., et al. (2011). Estimated HIV incidence in the United States, 2006–2009. PLOS ONE, 6(8), e17502.
  Rasch, G. (1980). Probabilistic models for some intelligence and attainment tests. Chicago, IL: University of Chicago Press.
  Rolland, J. S. (1994). Families, illness and disability. New York: Basic Books.
  Sanders-Phillips, K. (2002). Factors influencing HIV/AIDS in women of color. Public Health Reports, 117(Suppl 1), S151–S156.PubMed PubMedCentral
  Schumacher, W. E., Frick, M., Kauselmann, V., Maier-Hoyle, R., van der Vliet, R., & Babiel, R. (2007). Fully automated quantification of human immunodeficiency virus (HIV) type 1 RNA in human plasma by the COBAS AmpliPrep/COBAS Taqman system. Journal of Clinical Virology, 38, 304–312.PubMed CrossRef
  Semple, S. J. (1992). Conflict in Alzheimer’s caregiving families: Its dimensions and consequences. The Gerontologist, 32, 648–655.PubMed CrossRef
  Semple, S. J., Patterson, T. L., Temoshok, L. R., Straits-Tröster, K., Atkinson, J. H., Koch, W., & Grant, I. (1997). Family conflict and depressive symptoms: A study of HIV-seropositive men. AIDS and Behavior, 1, 53–60.CrossRef
  Senn, T. E., & Carey, M. P. (2008). HIV, STD, and sexual risk reduction for individuals with a severe mental illness: Review of the intervention literature. Current Psychiatry Review, 4, 87–100.CrossRef
  Senn, T., Carey, M., & Variable, P. (2010). The intersection of violence, substance use, negative affect, and STDs: Testing of a syndemic pattern among patients attending an urban STD clinic. Journal of the National Medical Association, 102, 614–620.PubMed PubMedCentral CrossRef
  Singer, M. (1996). A dose of drugs, a touch of violence, a case of AIDS: Conceptualizing the SAVA syndemic. Free Inquiry in Creative Sociology, 24, 99–110.
  Singer, M. (2009). Introduction to syndemics: A critical systems approach to public and community health. San Francisco, CA: Jossey-Bass Books.
  Singer, M., & Clair, S. (2003). Syndemics and public health: reconceptualizing disease in bio-social context. Medical Anthropology Quarterly, 17, 423–441.PubMed CrossRef
  Singer, M., & Romero-Daza, N. (1997). A notable connection between substance abuse, violence, and AIDS: Initial findings from research in the Puerto Rican community of Hartford. Hartford, CT: Hispanic Health Council.
  Stall, R., Mills, T. C., & Williamson, J. (2003). Association of cooccurring psychosocial health problems and increased vulnerability to HIV & AIDS among urban men who have sex with men. American Journal of Public Health, 93, 939–942.PubMed PubMedCentral CrossRef
  StataCorp. (2009). Stata statistical software, Rel. 11. College Station, TX: StataCorp LP.
  Straus, M. A. (1979). Measuring intra family conflict and violence: The Conflict Tactics (CT) Scales. Journal of Marriage & the Family, 41, 75–88.CrossRef
  Sullivan, K. A., Messer, L. C., & Quinlivan, E. B. (2015). Substance abuse, violence, and HIV/AIDS (SAVA) syndemic effects on viral suppression among HIV positive women of color. AIDS Patient Care and STDs, 29, S42–S48.PubMed PubMedCentral CrossRef
  Tobin, K. E., Kuramoto, S. J., Davey-Rothwell, M. A., & Latkin, C. A. (2011). The STEP into action study: A peer-based, personal risk network-focused HIV prevention intervention with injection drug users in Baltimore, Maryland. Addiction, 106, 366–375.PubMed PubMedCentral CrossRef
  Towner, W. J. (2008). The changing face of HIV infection. Permanente Journal, 12, 60–64.PubMed PubMedCentral CrossRef
  Tracy, E. M., & Martin, T. C. (2007). Children’s roles in the social networks of women in substance abuse treatment. Journal of Substance Abuse Treatment, 32, 81–88.PubMed CrossRef
  Wyatt, G. E. (2002). Does a history of trauma contribute to HIV risk for women of color? Implications for prevention and policy. American Journal of Public Health, 92, 660–665.PubMed PubMedCentral CrossRef
  Zea, M., Reisen, C., Poppen, P., Bianchi, F., & Echeverry, J. (2005). Disclosure of HIV status and psychological well-being among Latino gay and bisexual men. AIDS and Behavior, 9, 15–26.PubMed CrossRef
  Zierler, S., & Krieger, N. (1997). Reframing women’s risk: Social inequalities and HIV infection. Annual Review of Public Health, 18, 401–436.PubMed CrossRef
  
• 作者单位：Allysha C. Robinson (1)
  Amy R. Knowlton (2)
  Andrea C. Gielen (2)
  Joseph J. Gallo (3)
  
  1. Department of Surgery, Brigham and Women’s Hospital, Harvard Schools of Medicine and Public Health, Center for Surgery and Public Health, One Brigham Circle, 1620 Tremont Street, Suite BC-4-020-U, Boston, MA, 02134, USA
  2. Department of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
  3. Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
  
• 刊物类别：Behavioral Science
• 刊物主题：Psychology
  Health Psychology
  Clinical Psychology
  Public Health
  
• 出版者：Springer Netherlands
• ISSN：1573-3521

文摘

We evaluated a synergistic epidemic (syndemic) of substance use, mental illness, and familial conflict non-negotiation among HIV-positive injection drug users (IDU). Baseline BEACON study data was utilized. Latent class analyses identified syndemic classes. These classes were regressed on sex, viral suppression, and acute care non-utilization. Females were hypothesized to have higher syndemic burden, and worse health outcomes than males. Nine percent of participants had high substance use/mental illness prevalence (Class 4); 23 % had moderate levels of all factors (Class 3); 25 % had high mental illness (Class 2); 43 % had moderate substance use/mental illness (Class 1; N = 331). Compared to Classes 1–3, Class 4 was mostly female (p < .05), less likely to achieve viral suppression, and more likely to utilize acute care (p < .05). Interventions should target African-American IDU females to improve their risk of negative medical outcomes. Findings support comprehensive syndemic approaches to HIV interventions, rather than singular treatment methods. Keywords HIV Injection drug use Viral suppression Health disparities Syndemic theory African-Americans Health services research