Stellenwert der Heidelberg-Retina-Tomographie in der Glaukomdiagnostik

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• 作者：Prof. E.M. Hoffmann
• 关键词：Glaukomfrüherkennung ; Progression ; Verlaufsbeobachtung ; Flickervergleich ; Topographic ; Change ; Analyse ; Course observation ; Flicker comparison ; Topographic change analysis ; Glaucoma early detection ; Progression
• 刊名：Der Ophthalmologe
• 出版年：2015
• 出版时间：August 2015
• 年：2015
• 卷：112
• 期：8
• 页码：646-653
• 全文大小：1,153 KB
• 参考文献：1.Girkin C (2006) Grundlagen der konfokalen Laser-Scan-Technik für den Arzt. In: Fingeret M, Flanagan J, Liebmann J (Hrsg) HRT Fibel. Heidelberg Engineering, Heidelberg, S?1-
  2.Kesen MR, Spaeth GL, Henderer JD, Pereira ML, Smith AF, Steinmann WC (2002) Retina Tomograph Vs clinical impression in the diagnosis of glaucoma Am J Ophthalmol 133(5):613-16
  3.Strouthidis NG, White ET, Owen VM, Ho TA, Hammond CJ, Garway-Heath DF (2005) Factors affecting the test-retest variability of Heidelberg retina tomograph and Heidelberg retina tomograph II measurements. Br J Ophthalmol 89(11):1427-432
  4.Wollstein G, Garway-Heath DF, Hitchings RA (1998) Identification of early glaucoma cases with the scanning laser ophthalmoscope. Ophthalmology 105:1557-563View Article PubMed
  5.Verdonck N, Zeyen T, Van Malderen L, Spileers W (2002) Short-term intra-individual variability in Heidelberg retina tomograph II. Bull Soc Belge Ophtalmol 11:51-7
  6.Ford BA, Artes PH, McCormick TA, Nicolela MT, LeBlanc RP, Chauhan BC (2003) Comparison of data analysis tools for detection of glaucoma with the Heidelberg retina tomograph. Ophthalmology 110(6):1145-150View Article PubMed
  7.Zangwill LM, Jain S, Racette L, Ernstrom KB, Bowd C, Medeiros FA, Sample PA, Weinreb RN (2007) The effect of disc size and severity of disease on the diagnostic accuracy of the Heidelberg retina tomograph glaucoma probability score. Invest Ophthalmol Vis Sci 48:2653-660View Article PubMed
  8.Garway-Heath F (2006) Moorfields-Regressionsanalyse. In: Fingeret M, Flanagan JG, Liebmann J (Hrsg) HRT Fibel. Heidelberg Engineering, Heidelberg, S?31-1
  9.Swindale NV, Stjepanovic G, Chin A, Mikelberg FS (2000) Automated analysis of normal and glaucomatous optic nerve head topography images. Invest Ophthalmol Vis Sci 41:1730-742PubMed
  10.Coops A, Henson DB, Kwartz AJ, Artes PH (2006) Automated analysis of heidelberg retina tomograph optic disc images by glaucoma probability score. Invest Ophthalmol Vis Sci 47:5348-355View Article PubMed
  11.Harizman N, Zelefsky JR, Ilitchev E, Tello C, Ritch R, Liebmann JM (2006) Detection of glaucoma using operator-dependent versus operator-independent classification in the Heidelberg retinal tomograph-III. Br J Ophthalmol 90:1390-392PubMed Central View Article PubMed
  12.Moreno-Monta?és J, Antón A, García N, Mendiluce L, Ayala E, Sebastián A (2008) Glaucoma probability score vs Moorfields classification in normal, ocular hypertensive, and glaucomatous eyes. Am J Ophthalmol 145:360-68View Article PubMed
  13.Strouthidis NG, Demirel S, Asaoka R, Cossio-Zuniga C, Garway-Heath DF (2010) The Heidelberg retina tomograph glaucoma probability score: reproducibility and measurement of progression. Ophthalmology 117(4):724-29View Article PubMed
  14.Coops A, Henson DB, Kwartz AJ, Artes PH (2006) Automated analysis of heidelberg retina tomograph optic disc images by glaucoma probability score. Invest Ophthalmol Vis Sci 47(12):5348-355View Article PubMed
  15.Artes PH, Crabb DP (2010) Estimating normative limits of Heidelberg retina tomograph optic disc rim area with quantile regression. Invest Ophthalmol Vis Sci 51(1):355-61View Article PubMed
  16.Weinreb RN, Zangwill LM, Jain S, Becerra LM, Dirkes K, Piltz-Seymour JR, Cioffi GA, Trick GL, Coleman AL, Brandt JD, Liebmann JM, Gordon MO, Kass MA, OHTS CSLO Ancillary Study Group (2010) Predicting the onset of glaucoma: the confocal scanning laser ophthalmoscopy ancillary study to the Ocular hypertension treatment study. Ophthalmology 117(9):1674-683PubMed Central View Article PubMed
  17.Strouthidis NG, Gardiner SK, Owen VM, Zuniga C, Garway-Heath DF (2010) Predicting progression to glaucoma in ocular hypertensive patients. J Glaucoma 19(5):304-09PubMed
  18.Alencar LM, Bowd C, Weinreb RN, Zangwill LM, Sample PA, Medeiros FA (2008) Comparison of HRT-3 glaucoma probability score and subjective stereophotograph assessment for prediction of progression in glaucoma. Invest Ophthalmol Vis Sci 49(5):1898-906PubMed Central View Article PubMed
  
• 作者单位：Prof. E.M. Hoffmann (1)
  
  1. Augenklinik und Poliklinik, Universit?tsmedizin Mainz, Langenbeckstr. 1, 55131, Mainz, Deutschland
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Ophthalmology
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1433-0423

文摘

Background The Heidelberg retinal tomography (HRT) is a technique that has been used for more than 20 years for glaucoma diagnostics and management. Many hundreds of scientific investigations have tested the reliability and accuracy of HRT for the early diagnosis of glaucoma and just as many studies can be found on the detection of progression in glaucoma. It is still one of the leading imaging systems for the detection and follow-up of glaucoma. Hardware and statistical methods implemented for progression detection have been regularly updated by the company and internationally known glaucoma specialists. Methods Besides the analysis of stereometric parameters and trend analyses, the primary method for assessing glaucomatous change using the HRT?is the topographic change analysis (TCA),?a technique that compares the variability within a baseline?examination to that between baseline and follow-up examinations.Furthermore, the flicker comparison enables detection of small topographic changes over time. Conclusion The use of HRT does not replace clinical examinations but facilitates the assessment and management of glaucoma depending on observer experience. This imaging method will still have a significant value in the future for glaucoma diagnostics, with a special emphasis on assessment of progression.