Primary neuroendocrine carcinoma coexisting with hemangioma in the liver: Report of a case
详细信息 查看全文
- 作者：Tomohiko Akahoshi ; Hidefumi Higashi ; Satoru Tsuruta ; Kouichiro Tahara ; Toshifumi Matsumoto ; Hideya Takeuchi ; Shoichi Era ; Fuminori Fujita and Yoichi Muto
- 关键词：Hepatic neuroendocrine carcinoma ; Hemangioma
- 刊名：Surgery Today
- 出版年：2010
- 出版时间：February, 2010
- 年：2010
- 卷：40
- 期：2
- 页码：185-189
- 全文大小：349.5 KB
文摘
Primary hepatic neuroendocrine carcinoma is an extremely rare liver tumor. We herein report a case of primary hepatic neuroendocrine carcinoma coexisting with a hemangioma in a 66-year-old man. Ultrasonography, computed tomography, and magnetic resonance imaging showed a tumor (1.5 cm in diameter) coexisting with a hemangioma in the lateral segment of the liver. Liver biopsy showed malignant cells, and several examinations revealed no alternative primary source. We performed a lateral segmentectomy. Microscopically, the tumor cells had round to oval nuclei and eosinophilic cytoplasm, proliferated in thick trabeculae or solid nests, and formed a focal rosette pattern. Mitotic cells were frequently observed. Immunohistochemically, the tumor cells were positive for the endocrine markers chromogranin A, neuron-specific enolase, and neural cell adhesion molecule, but negative for α-fetoprotein and hepatocyte-specific antigen. The patient is still alive after 3 months, without recurrence.