Optimum dose of vitamin D for disease prevention in older people: BEST-D trial of vitamin D in primary care
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- 作者：H. Hin ; J. Tomson ; C. Newman ; R. Kurien ; M. Lay ; J. Cox…
- 关键词：Clinical trial ; Markers of vitamin D status ; Optimum dose ; Vitamin D
- 刊名：Osteoporosis International
- 出版年：2017
- 出版时间：March 2017
- 年：2017
- 卷：28
- 期：3
- 页码：841-851
- 全文大小：467KB
- 刊物类别：Medicine
- 刊物主题：Orthopedics; Endocrinology; Rheumatology;
- 出版者：Springer London
- ISSN：1433-2965
- 卷排序：28
文摘
SummaryThis trial compared the effects of daily treatment with vitamin D or placebo for 1 year on blood tests of vitamin D status. The results demonstrated that daily 4000 IU vitamin D3 is required to achieve blood levels associated with lowest disease risks, and this dose should be tested in future trials for fracture prevention.