Diagnosis and treatment of nonadjacent cryptococcal infections at the L1 and S1 vertebrae

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• 作者：Qi Lai ; Yuan Liu ; Xionglong Yu ; Xin Lv ; Qiang Wang ; Yibiao Zhou…
• 关键词：Cryptococcosis ; Bacterial infections and mycoses ; Bone diseases ; Cancer ; Spine
• 刊名：Der Orthopäde
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：46
• 期：1
• 页码：85-89
• 全文大小：1017KB
• 刊物主题：Orthopedics; Chiropractic Medicine; Conservative Orthopedics; Surgical Orthopedics; Sports Medicine; Traumatic Surgery;
• 出版者：Springer Medizin
• ISSN：1433-0431
• 卷排序：46

文摘

Cryptococcal spine infections are rare infections that are easy to misdiagnose and difficult to cure. Therefore, we report the case of a 25-year-old man who presented with nonspecific spinal lesions at L1 and S1. The patient underwent surgical removal of the lesions, and specimens were submitted for microbial identification, which identified a cryptococcal infection that was susceptible to amphotericin B. The patient exhibited marked improvement after receiving intravenous amphotericin B and remained asymptomatic (no back pain, fever, or other symptoms) at the 3‑ and 9‑month follow-ups. Similar cases of cryptococcal spine infections are rare, and we believe that our diagnostic findings and treatment experience may help improve the management of this rare disease.