Identification of 3-chloro-1,2-propandiol using molecularly imprinted composite solid-phase extraction materials

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• 作者：Yun Li ; Chuangmu Zheng ; Xiulan Sun ; Ben Ouyang…
• 关键词：3 ; MCPD ; Molecular imprinting ; Silica ; Microparticles ; Adsorption
• 刊名：Analytical and Bioanalytical Chemistry
• 出版年：2014
• 出版时间：October 2014
• 年：2014
• 卷：406
• 期：25
• 页码：6319-6327
• 全文大小：934 KB
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• 作者单位：Yun Li (1) (2)
  Chuangmu Zheng (1)
  Xiulan Sun (2)
  Ben Ouyang (2)
  Ping Ni (3)
  Yingzhi Zhang (2)
  
  1. Key Laboratory of Agro-food Safety and Quality of Ministry of Agriculture, Institute of Quality Standards and Testing Technology for Agro-products, Chinese Academy of Agricultural Sciences, No. 12, Zhongguancun South Street, Beijing, 100081, People’s Republic of China
  2. State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Synergetic Innovation Center of Food Safety and Nutrition, Jiangnan University, 1800 Lihu Avenue, Wuxi, Jiangsu, 214122, People’s Republic of China
  3. College of Tea & Food Science and Technology, Anhui Agricultural University, Hefei, Anhui, 230036, People’s Republic of China
  
• ISSN：1618-2650

文摘

A novel molecularly imprinted material based on silica microparticles was synthesized by surface polymerization?with 3-chloro-1,2-propandiol (3-MCPD) as a template molecule. The molecularly imprinted polymer (MIP) was characterized by infrared spectroscopy and scanning electron microscopy. The adsorption of 3-MCPD by MIP was measured by gas chromatography with electron capture detection (GC-ECD) and an equilibrium binding experiment. Scatchard analysis revealed that the maximum apparent binding capacities of the MIP and non-imprinted polymer (NIP) were 67.64 and 23.31?μmol/g, respectively. The new adsorbent was successfully used in solid-phase extraction (SPE) to selectively enrich and determine 3-MCPD in soy sauce samples. The MIP-SPE column achieves recoveries higher than 92.7?% with a relative standard deviation of less than 1.83?%. The MIP-SPE-GC protocol improved the selectivity and eliminated the effects of template leakage on quantitative analysis and could be used for the determination of 3-MCPD in other complex food samples. Graphical Abstract The MIP-SPE column developed by us achieves recoveries higher than 92.7 % with a relative standard deviation of less than 1.83 % for determining the 3-MCPD in the soy sauce matrix (mixed with 3-MCPD, 2-MPCD and 1,3-DCP).