Synthesis and characterization of fluorescent PEG-polyurethane with free carboxyl groups
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- 作者：Hong Yu Yang (1)
Xiu Mei Zhang (3)
Li Jie Duan (1)
Ming Yao Zhang (1)
Guang Hui Gao (1)
Hui Xuan Zhang (1) (2) - 关键词：Polyurethane ; pH sensitive ; Fluorescent ; Carboxyl groups
- 刊名：Journal of Polymer Research
- 出版年：2012
- 出版时间：September 2012
- 年：2012
- 卷：19
- 期：9
- 全文大小：408 KB
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Xiu Mei Zhang (3)
Li Jie Duan (1)
Ming Yao Zhang (1)
Guang Hui Gao (1)
Hui Xuan Zhang (1) (2)
1. Engineering Research Center of Synthetic Resin and Special Fiber, Ministry of Education, Changchun University of Technology, Changchun, 130012, China
3. Department of Radiology, The First Hospital of Jilin University, Changchun, 130021, China
2. Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130012, China - ISSN：1572-8935
文摘
A series of fluorescent multiblock PEG-polyurethane copolymers with free carboxyl groups were synthesized by one-step method and their chemical structure and properties were investigated. The multiblock PEG-polyurethane copolymers were composed of poly(ethylene glycol) (PEG), 1,6-hexamethylene diisocyanate, 2,2-bis(hydroxymethyl) propionic acid and a fluorescent dye erythrosine B (EB). The resulting polymers were examined by 1HNMR, FT-IR, gel permeation chromatography (GPC), ultraviolet visible spectroscopy (UV–vis), fluorescent spectroscopy. As a result, the UV–vis spectra showed that EB can be successfully conjugated into PEG-polyurethane during the one-step reaction. And the UV absorption peaks of samples were blue-shift and strengthened with decreasing of pH values, indicating that PEG-polyurethane-EB can be a pH-dependent fluorescent probe in a broad pH range. We expect that more applications would be possible for the fluorescent PEG-polyurethane with free carboxyl groups owing to its free functional groups and simultaneously imaging along with pH values.