Temporal changes in mean HbA1c in a general population: comparisons between 1997 and 2002, the Japan National Diabetes Surveys

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• 作者：Yayoi Yamamoto ; Tomoko Nakagami ; Tetsuji Yokoyama…
• 关键词：Japan National Diabetes Survey ; HbA1c ; Time trend ; Prevalence
• 刊名：Diabetology International
• 出版年：2015
• 出版时间：June 2015
• 年：2015
• 卷：6
• 期：2
• 页码：83-90
• 全文大小：683 KB
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• 作者单位：Yayoi Yamamoto (1)
  Tomoko Nakagami (1)
  Tetsuji Yokoyama (2)
  Yasuko Uchigata (1)
  Nobuo Yoshiike (3)
  
  1. Diabetes Center, Tokyo Women’s Medical University School of Medicine, 8-1 Kawada-cho, Shinjuku-ku, 162-8666, Tokyo, Japan
  2. Department of Health Promotion, National Institute of Public Health, Saitama, Japan
  3. Department of Health Science, Aomori University of Health and Welfare, Aomori, Japan
  
• 刊物主题：Diabetes; Metabolic Diseases; Endocrinology;
• 出版者：Springer Japan
• ISSN：2190-1686

文摘

Aims This study examines the change in mean hemoglobin A_1c (HbA_1c) from 1997 to 2002 and evaluates factors associated with HbA_1c, by analyzing two points?cross-sectional data from the?Japan National Diabetes Surveys. Methods The study included 2,095 men and 3,340 women in 1997, and 1,960 men and 3,115 women in 2002 without a previous history of diabetes. Differences between the two surveys were compared. A multivariable linear regression model was used to identify factors related to HbA_1c. Results The mean HbA_1c was 0.15?% higher in 2002 than 1997 in men (5.29?to?5.44?%, P?<?0.001) and 0.14?% higher in women without a previous history of diabetes (5.33?to?5.47?%, P?<?0.001). In men, mean BMI increased (23.1?to?23.7?kg/m2, P?<?0.001), SBP decreased (137?to?133?mmHg, P?=?0.006), and the proportion of current smokers (53?to?45?%, P?<?0.001) and current drinkers decreased (52?to?48?%, P?=?0.047). In women, mean BMI showed no change and SBP decreased (131?to?127?mmHg, P?=?0.020). Age, BMI, current non-drinker, and the time trend (5?years from 1997 to 2002) were associated with HbA_1c in both sexes and current smoking and daily footsteps were associated with HbA_1c only in men. Conclusions The mean HbA_1c increased by 0.14-.15?% in both sexes from 1997 to 2002 among Japanese people without a previous history of diabetes. The increase in HbA_1c from 1997 to 2002 could partly be related to the increase of BMI in men. Such temporal changes of HbA_1c should be further investigated in the national data to search for contributing factors to promote health care related to diabetes in Japan.