参考文献:1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin. 2013;63:11鈥?0. CrossRef 2. Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA Cancer J Clin. 2010;60:277鈥?00. CrossRef 3. Butturini G, Stocken DD, Wente MN, Jeekel H, Klinkenbijl JH, Bakkevold KE, / et al. Influence of resection margins and treatment on survival in patients with pancreatic cancer: meta-analysis of randomized controlled trials. Arch Surg. 2008;143:75鈥?3. CrossRef 4. Vogelstein B, Kinzler KW. Cancer genes and the pathways they control. Nat Med. 2004;10:789鈥?9. CrossRef 5. Hingorani SR, Wang L, Multani AS, Combs C, Deramaudt TB, Hruban RH, / et al. Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice. Cancer Cell. 2005;7:469鈥?3. CrossRef 6. Shen R, Wang Q, Cheng S, Liu T, Jiang H, Zhu J, / et al. The biological features of PanIN initiated from oncogenic Kras mutation in genetically engineered mouse models. Cancer Lett. 2013;339:135鈥?3. CrossRef 7. Yu M, Ting DT, Stott SL, Wittner BS, Ozsolak F, Paul S, / et al. RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis. Nature. 2012;487:510鈥?. CrossRef 8. White BD, Chien AJ, Dawson DW. Dysregulation of Wnt/beta-catenin signaling in gastrointestinal cancers. Gastroenterology. 2012;142:219鈥?2. CrossRef 9. Morris JP, Wang SC, Hebrok M, Hedgehog KRAS. Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma. Nat Rev Cancer. 2010;10:683鈥?5. CrossRef 10. Qiu MT, Hu JW, Yin R, Xu L. Long noncoding RNA: an emerging paradigm of cancer research. Tumour Biol. 2013;34:613鈥?0. CrossRef 11. Yu G, Yao W, Wang J, Ma X, Xiao W, Li H, / et al. LncRNAs expression signatures of renal clear cell carcinoma revealed by microarray. PLoS One. 2012;7:e42377. CrossRef 12. Han Y, Liu Y, Nie L, Gui Y, Cai Z. Inducing cell proliferation inhibition, apoptosis, and motility reduction by silencing long noncoding ribonucleic acid metastasis-associated lung adenocarcinoma transcript 1 in urothelial carcinoma of the bladder. Urology. 2013;8:209. e1-7. 13. Zhu Z, Gao X, He Y, Zhao H, Yu Q, Jiang D, / et al. An insertion/deletion polymorphism within RERT-lncRNA modulates hepatocellular carcinoma risk. Cancer Res. 2012;72:6163鈥?2. CrossRef 14. Yuan SX, Yang F, Yang Y, Tao QF, Zhang J, Huang G, / et al. Long noncoding RNA associated with microvascular invasion in hepatocellular carcinoma promotes angiogenesis and serves as a predictor for hepatocellular carcinoma patients鈥?poor recurrence-free survival after hepatectomy. Hepatology. 2012;56:2231鈥?1. hep.25895" target="_blank" title="It opens in new window">CrossRef 15. Yang F, Zhang L, Huo XS, Yuan JH, Xu D, Yuan SX, / et al. Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans. Hepatology. 2011;54:1679鈥?9. hep.24563" target="_blank" title="It opens in new window">CrossRef 16. Hingorani SR, Petricoin EF, Maitra A, Rajapakse V, King C, Jacobetz MA, / et al. Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse. Cancer Cell. 2003;4:437鈥?0. CrossRef 17. Qian J, Niu J, Li M, Chiao PJ, Tsao MS. In vitro modeling of human pancreatic duct epithelial cell transformation defines gene expression changes induced by K-ras oncogenic activation in pancreatic carcinogenesis. Cancer Res. 2005;65:5045鈥?3. CrossRef 18. Wang Q, Liu H, Liu T, Shu S, Jiang H, Cheng S, / et al. BRCA2 dysfunction promotes malignant transformation of pancreatic intraepithelial neoplasia. Anticancer Agents Med Chem. 2013;13:261鈥?. CrossRef 19. Dong W, Shen R, Wang Q, Gao Y, Qi X, Jiang H. Y / et al. Sp1 upregulates expression of TRF2 and TRF2 inhibition reduces tumorigenesis in human colorectal carcinoma cells. Cancer Biol Ther. 2009;8:2166鈥?4. 20. Hotz B, Arndt M, Dullat S, Bhargava S, Buhr HJ, Hotz HG. Epithelial to mesenchymal transition: expression of the regulators snail, slug, and twist in pancreatic cancer. Clin Cancer Res. 2007;13:4769鈥?6. CrossRef 21. Froeling FE, Feig C, Chelala C, Dobson R, Mein CE, Tuveson DA, / et al. Retinoic acid-induced pancreatic stellate cell quiescence reduces paracrine Wnt-beta-catenin signaling to slow tumor progression. Gastroenterology. 2011;14:1486鈥?7. CrossRef 22. Fiorini C, Menegazzi M, Padroni C, Dando I, Dalla Pozza E, Gregorelli A, / et al. Autophagy induced by p53-reactivating molecules protects pancreatic cancer cells from apoptosis. Apoptosis. 2013;18:337鈥?6. CrossRef 23. Guo X, Wang M, Jiang J, Xie C, Peng F, Li X, / et al. Balanced Tiam1-Rac1 and RhoA drives proliferation and invasion of pancreatic cancer cells. Mol Cancer Res. 2013;11:230鈥?. CrossRef 24. Timpson P, McGhee EJ, Morton JP, von Kriegsheim A, Schwarz JP, Karim SA, / et al. Spatial regulation of RhoA activity during pancreatic cancer cell invasion driven by mutant p53. Cancer Res. 2011;71:747鈥?7. CrossRef 25. Jha S, Dutta A. RVB1/RVB2: running rings around molecular biology. Mol Cell. 2009;34:521鈥?3. CrossRef 26. Gabrovska PN, Smith RA, Haupt LM, Griffiths LR. Investigation of two Wnt signalling pathway single nucleotide polymorphisms in a breast cancer-affected Australian population. Twin Res Hum Genet. 2011;14:562鈥?. CrossRef 27. Singh AP, Bafna S, Chaudhary K, Venkatraman G, Smith L, Eudy JD, / et al. Genome-wide expression profiling reveals transcriptomic variation and perturbed gene networks in androgen-dependent and androgen-independent prostate cancer cells. Cancer Lett. 2008;259:28鈥?8. CrossRef 28. Ostenfeld MS, Bramsen JB, Lamy P, Villadsen SB, Fristrup N, Sorensen KD, / et al. miR-145 induces caspase-dependent and -independent cell death in urothelial cancer cell lines with targeting of an expression signature present in Ta bladder tumors. Oncogene. 2010;29:1073鈥?4. CrossRef
刊物类别:Biomedical and Life Sciences
刊物主题:Biomedicine Pharmacology and Toxicology Pharmacy Biochemistry Medical Law Biomedical Engineering