Two-level multi-pinhole collimator for SPECT imaging using a small-field-of-view gamma camera

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• 作者：Jaekeon Bae ; Seungbin Bae ; Soo-young Lee…
• 关键词：Single ; photon emission computed tomography ; Multi ; pinhole collimator ; Target oriented system ; Image reconstruction ; Limited ; angle reconstruction ; Organ ; specific application
• 刊名：Journal of the Korean Physical Society
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：70
• 期：2
• 页码：192-200
• 全文大小：
• 刊物主题：Physics, general; Theoretical, Mathematical and Computational Physics; Particle and Nuclear Physics;
• 出版者：The Korean Physical Society
• ISSN：1976-8524
• 卷排序：70

文摘

The aim of this study was to develop a high-throughput imaging method for single-photon emission computed tomography. We developed a target-oriented multi-pinhole collimator and limitedangle method for scanning small organs such as the thyroid. To maximize the resolution and the sensitivity of the collimator, we designed a two-level multi-pinhole collimator whose levels were optimized for concave body contours. One level had a center hole whereas the other had surrounding holes. The limited-angle scanning method was employed to obtain tomographic images by using the collimator located near the body contour of the target, and a corresponding image reconstruction algorithm was implemented. A small-field-of-view gamma camera was used to achieve a smaller footprint. The design of the collimator also considered the dimensions of used gamma camera. Evaluation studies were conducted using the Geant4 application for tomographic emission. The results showed the resolution of the proposed collimator to be more than twice that of the previously designed multi-pinhole collimator while maintaining the same efficiency. Given that the designed collimator can be changed by simply replacing the center hole, the suggested imaging method is suitable for studying not only the thyroid but also any organ whose diameter is less than 90 mm.