Delayed Administration of WP1066, an STAT3 Inhibitor, Ameliorates Radiation-Induced Lung Injury in Mice

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• 作者：Jiahua Yu ; Xiaopeng Yuan ; Yang Liu ; Kaishuo Zhang ; Jie Wang ; Haowen Zhang…
• 关键词：WP1066 ; STAT3 ; Radiation pneumonitis ; Inflammation ; Cytokine
• 刊名：Lung
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：194
• 期：1
• 页码：67-74
• 全文大小：1,536 KB
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• 作者单位：Jiahua Yu (1)
  Xiaopeng Yuan (1)
  Yang Liu (1)
  Kaishuo Zhang (1)
  Jie Wang (1)
  Haowen Zhang (1)
  Fenju Liu (1)
  
  1. Department of Radiobiology, School of Radiation Medicine and Protection, Medical College of Soochow University, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou, 215123, People’s Republic of China
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Pneumology and Respiratory System
  
• 出版者：Springer New York
• ISSN：1432-1750

文摘

Purpose The present study was designed to investigate the effects of WP1066, a specific inhibitor of STAT3 signaling, on radiation-induced lung injury in mice.