Analysis of risk factors of ST-segment elevation myocardial infarction in young patients

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• 作者：Wang Yunyun ; Li Tong ; Liu Yingwu ; Liu Bojiang ; Wang Yu…
• 关键词：Antecedent angina pectoris ; Fibrinogen ; Glycated hemoglobin ; Risk factors ; ST ; segment elevation myocardial infarction ; Young patients
• 刊名：BMC Cardiovascular Disorders
• 出版年：2014
• 出版时间：December 2014
• 年：2014
• 卷：14
• 期：1
• 全文大小：266 KB
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• 刊物主题：Cardiology; Cardiac Surgery; Angiology; Blood Transfusion Medicine; Internal Medicine;
• 出版者：BioMed Central
• ISSN：1471-2261

文摘

Background Acute myocardial infarction (AMI) is often present in old populations and rare in young people. Its incidence significantly increased recent years. The mechanism and disease course of AMI in young people are probably different from that in old population. The aim of this study was to analyze clinical risk factors of STEMI in young patients. Methods Data was collected from consecutive patients ?44 years of age (young; n = 86) and 60-4 years of age (old; n = 65) diagnosed with STEMI, and 79 young age-matched patients without coronary artery disease (CAD), hospitalized between January 2009 and June 2013. Results The young STEMI group had a significantly higher proportion of males (88.37 vs. 53.16%; P vs. 49.37%; P vs. 32.91%; P STEMI patients also had significantly higher levels of fasting blood sugar (6.39 vs. 5.25 mmol/L; P HbA1c) (6.26 vs. 5.45%; P vs. 4.65 mmol/L, P vs. 2.87; P STEMI group, young STEMI patients had significantly higher proportions of males (88.37 vs. 63.08%; P vs. 41.54%; P vs. 18.46%; P STEMI patients also lower Fib (3.39 vs. 3.88 g/L; P STEMI (13.95 vs. 29.23%; P STEMI group. Logistic regression analysis indicated that male sex (OR = 5.891), smoking (OR = 3.500), family history of early CAD (OR = 3.194), Fib (OR = 2.414) and HbA1c (OR = 1.515) are associated with STEMI in young patients. Conclusion In addition to previously recognized risk factors (male sex, smoking and family history of early CAD), Fib and HbA1c are associated with STEMI in individuals ?44 years of age without antecedent angina pectoris.