Diaphragmatic Motion Studied by M-mode Ultrasonography in Combined Pulmonary Fibrosis and Emphysema

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• 作者：Li He (1)
  Wanguang Zhang (2)
  Jiahong Zhang (1)
  Le Cao (3)
  Lan Gong (3)
  Jingping Ma (1)
  He Huang (1)
  Jinwu Zeng (1)
  Chuanbin Zhu (1)
  Jianhua Gong (1)
  Yongjian Xu (4)
  Zhenxiang Zhang (4)
  Jianping Zhao (4)
  Huilan Zhang (4)
  
• 关键词：Combined pulmonary fibrosis and emphysema ; Chronic obstructive pulmonary disease ; Diaphragm ; Idiopathic pulmonary fibrosis
• 刊名：Lung
• 出版年：2014
• 出版时间：August 2014
• 年：2014
• 卷：192
• 期：4
• 页码：553-561
• 全文大小：880 KB
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• 作者单位：Li He (1)
  Wanguang Zhang (2)
  Jiahong Zhang (1)
  Le Cao (3)
  Lan Gong (3)
  Jingping Ma (1)
  He Huang (1)
  Jinwu Zeng (1)
  Chuanbin Zhu (1)
  Jianhua Gong (1)
  Yongjian Xu (4)
  Zhenxiang Zhang (4)
  Jianping Zhao (4)
  Huilan Zhang (4)
  
  1. Department of Respiratory Medicine, Jingzhou Hospital of Tongji Medical College, Huazhong University of Science and Technology, No. 1, Ren Min Road, JingZhou District, JingZhou, 434020, Hu Bei Province, China
  2. Department of Surgery, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, No. 1095, Jie Fang Road, Han Kou District, Wu Han, 430030, Hu Bei Province, China
  3. Ultrasonographic Medicine, Jingzhou Hospital of Tongji Medical College, Huazhong University of Science and Technology, No. 1, Ren Min Road, JingZhou District, JingZhou, 434020, Hu Bei Province, China
  4. Department of Respiratory Medicine, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, No. 1095, Jie Fang Road, Han Kou District, Wu Han, 430030, Hu Bei Province, China
  
• ISSN：1432-1750

文摘

Background The coexistence of emphysema and pulmonary fibrosis is known as combined pulmonary fibrosis and emphysema (CPFE). The aim of this study was to compare diaphragmatic motion measured by M-mode ultrasonography of patients with CPFE, idiopathic pulmonary fibrosis (IPF), and chronic obstructive pulmonary disease (COPD). Methods Pulmonary function, high-resolution computed tomography (HRCT), and diaphragmatic motion were examined in patients with CPFE (n?=?25), IPF (n?=?18), and COPD (n?=?60), and in healthy controls (n?=?21). Diaphragmatic motions were measured on M-mode ultrasonographic images during quiet breathing and deep breathing. Results There were no significant differences in right or left diaphragmatic motion during quiet breathing among the four groups, whereas differences were significant in right and left motion during deep breathing. Diaphragmatic motion in CPFE patients was the lowest among the four groups. COPD patients, especially those with severe COPD, showed significantly lower diaphragmatic motion than IPF patients or healthy controls. There were no differences in diaphragmatic motion between IPF patients and healthy controls. Right diaphragmatic motions during deep breathing were negatively correlated with emphysema scores (r?=??.606, p?HRCT. Conclusions Diaphragmatic weakness was found in CPFE patients. Emphysema but not fibrosis may be one cause of limited diaphragmatic motion in patients with CPFE. M-mode ultrasonographic evaluation of diaphragmatic motion during deep breathing may be a useful tool in diagnosing CPFE and in discriminating CPFE patients from IPF or COPD patients.