Voltammetric determination of levofloxacin using a glassy carbon electrode modified with poly(o-aminophenol) and graphene quantum dots
详细信息 查看全文
- 作者：Jing-Yi Huang ; Ting Bao ; Tian-Xing Hu ; Wei Wen ; Xiu-Hua Zhang…
- 关键词：Antibiotic ; Differential pulse voltammetry ; Linear sweep voltammetry ; Milk samples ; Nanoparticles
- 刊名：Microchimica Acta
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：184
- 期：1
- 页码：127-135
- 全文大小：
- 刊物类别：Chemistry and Materials Science
- 刊物主题：Nanochemistry; Nanotechnology; Characterization and Evaluation of Materials; Analytical Chemistry; Microengineering;
- 出版者：Springer Vienna
- ISSN：1436-5073
- 卷排序：184
文摘
A strategy was developed for the voltammetric determination of the antibiotic drug levofloxacin (LV) based on a glassy carbon electrode modified with a composite consisting of poly(o-aminophenol) and graphene quantum dots (PoAP/GQD) that was fabricated by electropolymerization. The PoAP/GQD composite provides a large surface area and sensing interface and strongly promotes the oxidation current of LV. Under optimal conditions, the modified GCE displays an oxidation peak current (best measured at a working voltage of 1.05 V vs. SCE) that is linearly related to the levofloxacin concentration in the range from 0.05 to 100 μM, and the detection limit is 10 nM (at an S/N of 3). The method was applied to the determination of levofloxacin in spiked milk samples where is gave recoveries between 96.0 and 101.0 %.