Paclitaxel-Coated Balloon for Femoropopliteal Artery Disease

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• 作者：Saurabh Mehrotra ; Ganesh Paramasivam ; Sundeep Mishra
• 关键词：Peripheral arterial disease ; Femoropopliteal artery disease ; Percutaneous transluminal angioplasty ; Drug ; coated balloon ; Drug ; eluting balloon ; Paclitaxel ; coated balloon
• 刊名：Current Cardiology Reports
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：19
• 期：2
• 全文大小：
• 刊物主题：Cardiology;
• 出版者：Springer US
• ISSN：1534-3170
• 卷排序：19

文摘

Purpose of the ReviewPercutaneous transluminal angioplasty is an established form of therapy for femoropopliteal artery disease. Currently, percutaneous transluminal angioplasty (PTA) is carried out using standard balloon with or without deployment of a stent but is associated with a high rate of restenosis and stent-related complications. Treatment options for restenosis, especially in-stent restenosis, are limited. Drug-coated balloons promise to reduce the rates of restenosis by effective delivery of antiproliferative agent (paclitaxel) directly to vessel wall without the need for a permanent implant. In this review, we look at the technology and rationale behind drug-coated balloons and examine the evidence available so far.