Alternaria arborescens Infection in a Healthy Individual and Literature Review of Cutaneous Alternariosis
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- 作者：Wenying Hu ; Yuping Ran ; Kaiwen Zhuang ; Jebina Lama ; Chaoliang Zhang
- 关键词：Alternaria arborescens ; Alternariosis ; Cutaneous ; Itraconazole
- 刊名：Mycopathologia
- 出版年：2015
- 出版时间：February 2015
- 年：2015
- 卷：179
- 期：1-2
- 页码：147-152
- 全文大小：711 KB
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- 刊物主题：Life Sciences
Microbiology
Medical Microbiology
Plant Sciences
Microbial Ecology- 出版者：Springer Netherlands
- ISSN：1573-0832
文摘
A 28-year-old man presented at our clinic with 1-month history of an ulcer covered with crust on his left anterior tibia. Based on the morphological features and molecular identification, the patient was diagnosed as cutaneous alternariosis caused by Alternaria arborescens. He was successfully cured by oral itraconazole and topical use of 0.25?% liposomal amphotericin B. A review of published studies revealed 29 cases of cutaneous alternariosis. Most cases (90?%) occurred in immunosuppressed patients; itraconazole (59?%) and voriconazole (24?%) are the most effective treatments of choices.