Trends on polymer- and lipid-based nanostructures for parenteral drug delivery to tumors
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- 作者：Elham Ajorlou ; Ahmad Yari Khosroushahi
- 关键词：Active targeting ; Cancer ; Control release ; Sustain release ; Passive targeting
- 刊名：Cancer Chemotherapy and Pharmacology
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：79
- 期：2
- 页码：251-265
- 全文大小：
- 刊物类别：Biomedical and Life Sciences
- 刊物主题：Oncology; Pharmacology/Toxicology; Cancer Research;
- 出版者：Springer Berlin Heidelberg
- ISSN：1432-0843
- 卷排序：79
文摘
PurposeThe dawn of the state-of-the-art methods of cancer treatments, nano-based delivery systems, has dispensed with the mainstream chemotherapy for being inadequate in yielding productive results and the numerous reported side effects. The popularity of this complementary approach in the course of the last two decades has been primarily attributed to its capacity to elevate the therapeutic index of anticancer drugs as well as removing the impassable delivery barriers in solid tumors with the minimal damage to the normal tissues.