AB-8与D101两种吸附树脂对吸附人参皂苷Re效果考察
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摘要
人参皂苷Re是天然产物人参提取物中重要的药用成分,具有多种药理作用。目前关于人参单体的分离纯化主要采用大孔吸附树脂法,但关于其吸附作用效果分析未得到系统研究。本文利用企业现有技术分别利用D101和AB-8两种大孔吸附树脂考察了两种树脂吸附人参皂苷Re的动力学性能和热力学性能,同时分析了两种树脂的吸附作用机理,为系统利用吸附树脂纯化天然产物提供技术参考。
Ginsenoside Re is an important medicinal ingredient in ginseng extract of natural products, and it has many pharmacological effects. At present, the separation and purification of ginseng monomers mainly use macroporous adsorption resin, but the adsorption effect has not been systematically analyzed. In this paper, D101 and AB-8 macroporous adsorbents were used to investigate the kinetics and thermodynamic properties of the two resins for adsorbing ginsenoside Re. The adsorption mechanism of the two resins were also analyzed, which could provide technical reference for the purification of natural products by resins.
Ginsenoside Re is an important medicinal ingredient in ginseng extract of natural products, and it has many pharmacological effects. At present, the separation and purification of ginseng monomers mainly use macroporous adsorption resin, but the adsorption effect has not been systematically analyzed. In this paper, D101 and AB-8 macroporous adsorbents were used to investigate the kinetics and thermodynamic properties of the two resins for adsorbing ginsenoside Re. The adsorption mechanism of the two resins were also analyzed, which could provide technical reference for the purification of natural products by resins.
引文
[1]姚培培.人参皂苷Re改善脂代谢的作用机制研究[D].青岛:青岛大学,2014.
[2]曹泰山,王丹.人参皂苷Rg1与人参皂苷Re含量测定方法的研究[J].时珍国医国药,2005,16(8):739-740.
[3]陈兆耀,刘新峰,徐格林.人参皂苷改善认知功能作用的研究进展[J].中国老年学杂志,2011,31(24):4980-4982.
[4]孔祥怡,郝利铭,苏晓薇,等.人参皂苷Re对慢性缺血致血管性痴呆大鼠行为学及形态学的影响[J].中国老年学杂志,2015,35(21):6033-6036.
[5]曲相如.人参皂苷Re对大鼠心肌缺血再灌注损伤的保护作用及机制[D].长春:吉林大学,2008.
[6]曾和松,刘正湘,刘晓春.人参皂苷Rb1与Re抗大鼠实验性缺血再灌注心肌细胞凋亡及相关基因蛋白表达[J].中华物理医学与康复杂志,2003,25(7):20-23.
[7]吕爽.人参皂苷Re的抗休克作用[D].沈阳:沈阳药科大学,2006.
[8]BAYRAMOGLU G,ALTINTAS B,YAKUP ARICA M.Adsorption kinetics and thermodynamic parameters of cationic dyes from aqueous solutions by using a new strong cation—exchange resin[J].Chemical Engineering Journal,2009,152(2/3):339-346.
[9]王跃生,王洋.大孔吸附树脂研究进展[J].中国中药杂志,2006,31(12):961-965.
[10]董漪,吴虹.大孔吸附树脂提取及纯化中药研究进展[J].安徽中医学院学报,2012,31(3):76-77.
[11]耿明江,董丽,尚校军,等.D101大孔树脂对桃花红色素吸附行为的研究[J].食品工业科技,2008,29(07):85-87.
[2]曹泰山,王丹.人参皂苷Rg1与人参皂苷Re含量测定方法的研究[J].时珍国医国药,2005,16(8):739-740.
[3]陈兆耀,刘新峰,徐格林.人参皂苷改善认知功能作用的研究进展[J].中国老年学杂志,2011,31(24):4980-4982.
[4]孔祥怡,郝利铭,苏晓薇,等.人参皂苷Re对慢性缺血致血管性痴呆大鼠行为学及形态学的影响[J].中国老年学杂志,2015,35(21):6033-6036.
[5]曲相如.人参皂苷Re对大鼠心肌缺血再灌注损伤的保护作用及机制[D].长春:吉林大学,2008.
[6]曾和松,刘正湘,刘晓春.人参皂苷Rb1与Re抗大鼠实验性缺血再灌注心肌细胞凋亡及相关基因蛋白表达[J].中华物理医学与康复杂志,2003,25(7):20-23.
[7]吕爽.人参皂苷Re的抗休克作用[D].沈阳:沈阳药科大学,2006.
[8]BAYRAMOGLU G,ALTINTAS B,YAKUP ARICA M.Adsorption kinetics and thermodynamic parameters of cationic dyes from aqueous solutions by using a new strong cation—exchange resin[J].Chemical Engineering Journal,2009,152(2/3):339-346.
[9]王跃生,王洋.大孔吸附树脂研究进展[J].中国中药杂志,2006,31(12):961-965.
[10]董漪,吴虹.大孔吸附树脂提取及纯化中药研究进展[J].安徽中医学院学报,2012,31(3):76-77.
[11]耿明江,董丽,尚校军,等.D101大孔树脂对桃花红色素吸附行为的研究[J].食品工业科技,2008,29(07):85-87.