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以周围神经损害为主的变应性肉芽肿性血管炎1例误诊分析
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摘要
<正>变应性肉芽肿性血管炎(allergic granulomatous angitis,AGA),亦称Churg-Strauss综合征(Churg-Strauss syndrome,CSS),是一种罕见的以哮喘、过敏性鼻炎、嗜酸性粒细胞增多为主要表现的肉芽肿性坏死性小血管血管炎,至今病因不明,病理特点是受累组织大量嗜酸性粒细胞浸润和血管外肉芽肿形成,主要累及肺、心、肾、皮肤和周围神经[1]。我科
        
引文
[1] Natsugoe S, Matsumoto M, Okumura H, et al. Initial metastatic,including micrometastatic, sites of lymph nodes in esophageal squamous cell carcinoma[J]. J Surg Oncol, 2014, 89:6-11.
    [2] Masi AT, Hunder GG, Lie JT, et al. The American College of Rheumatology 1990 criteria for the classafication of Churg-Strauss syndrome(allergic granulomatosis and angiitis)[J]. Arthritis Rheum,1990,33:1094.
    [3] Pankhurst T, Savage CO. Pathogenic role of anti-neutrophil cytoplasmic antibodies invasculit[J]. Curr Opin Pharmacol, 2016, 6:190-119.
    [4] Stassijns G, Vanderstraeten G, Troise WR, et al. Neuropathy associated with Churg-S trauss syndrome(allergic granulomatous angiitis)[J]. Electrophysiologr Clin Neurophysiol, 2014, 34:391-395.
    [5] Koike H, Akiyama K, Saito T. Intravenous immunoglobulin for chronic residual peripheral neuropathy in eosinophilic granulomatosis with polyangiitis(Churg-Strauss syndrome):a multicenter, double-blind trial[J]. J Neurol, 2015, 262:11-15.
    [6] Guillevin L. Advances in the treatments of systemic vasculitides[J].Clin Rev Allergy Immunol, 2016, 35:72-78.

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