蛹虫草口服液澄清工艺的研究
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摘要
目的:对蛹虫草口服液的澄清工艺进行优化。方法:以总多糖保留率为指标,采用正交试验考察考察体系pH、壳聚糖加入量和温度等因素对澄清工艺的影响。结果:最佳澄清工艺条件为:pH为4.0、壳聚糖加入量为0.2%和温度为60℃。结论:壳聚糖对蛹虫草口服液的澄清工艺操作简便易行,稳定可靠,为蛹虫草口服液的生产工艺改进提供科学依据。
Objective: To optimize the clarification process of Cordyceps militaris oral liquid. Methods: The effects of chitosan amount,system pH and temperature on the clarification process were investigated by orthogonal test with the retention rate of the total polysaccharide as the index. Results: The optimum conditions for the clarification were as follows: the pH value was 4.0,the amount of chitosan was 0.2% and the temperature was 60℃. Conclusion: The clarification technology with chitosan for Cordyceps militaris oral liquid is simple,stable and reliable,which provides scientific basis for the production process improvement of Cordyceps militaris oral liquid.
Objective: To optimize the clarification process of Cordyceps militaris oral liquid. Methods: The effects of chitosan amount,system pH and temperature on the clarification process were investigated by orthogonal test with the retention rate of the total polysaccharide as the index. Results: The optimum conditions for the clarification were as follows: the pH value was 4.0,the amount of chitosan was 0.2% and the temperature was 60℃. Conclusion: The clarification technology with chitosan for Cordyceps militaris oral liquid is simple,stable and reliable,which provides scientific basis for the production process improvement of Cordyceps militaris oral liquid.
引文
1吴勇,陈卫东.蛹虫草药理作用研究概述[J].中国药师,2011,14(5):732-734
2孙桂菊,左平国.枸杞多糖功效研究及应用进展[J].东南大学学报(医学版),2010,29(2):209-215
3柏冬志,东方,唐文婷,等.黄芪多糖药理作用的研究进展[J].黑龙江医药,2014,27(1):103-106
4崔思娇,杨光照,于士龙,等.蛹虫草口服液提取工艺的研究[J].中医药导报,2017,23(19):53-60
5丁城,刘璐,胡勇.梨醋澄清工艺的探究[J].中国调味品,2017,42(2):112-116
6任素宁,孙祖莉,齐志强,等.樱桃低醇酒澄清工艺的研究[J].中国酿造,2017,36(4):158-162
7李鹏程,张本才,陈战国.正交试验法优化太白泡沙参总多糖的澄清工艺[J].中国中药杂志,2008,33(11):1266-1268
8陆萍,倪东杰,郭良君.壳聚糖澄清剂与醇沉法制备健骨口服液的比较[J].中国药师,2012,15(11):1580-1582
9孙姣.中药提取液絮凝除杂效果及机理研究[D].天津:天津大学博士学位论文,2014
10单丹彤,谢飞,李若慧.壳聚糖的生物医学特性与其结构的关系研究进展[J].化工新型材料,2012,40(6):19-21
2孙桂菊,左平国.枸杞多糖功效研究及应用进展[J].东南大学学报(医学版),2010,29(2):209-215
3柏冬志,东方,唐文婷,等.黄芪多糖药理作用的研究进展[J].黑龙江医药,2014,27(1):103-106
4崔思娇,杨光照,于士龙,等.蛹虫草口服液提取工艺的研究[J].中医药导报,2017,23(19):53-60
5丁城,刘璐,胡勇.梨醋澄清工艺的探究[J].中国调味品,2017,42(2):112-116
6任素宁,孙祖莉,齐志强,等.樱桃低醇酒澄清工艺的研究[J].中国酿造,2017,36(4):158-162
7李鹏程,张本才,陈战国.正交试验法优化太白泡沙参总多糖的澄清工艺[J].中国中药杂志,2008,33(11):1266-1268
8陆萍,倪东杰,郭良君.壳聚糖澄清剂与醇沉法制备健骨口服液的比较[J].中国药师,2012,15(11):1580-1582
9孙姣.中药提取液絮凝除杂效果及机理研究[D].天津:天津大学博士学位论文,2014
10单丹彤,谢飞,李若慧.壳聚糖的生物医学特性与其结构的关系研究进展[J].化工新型材料,2012,40(6):19-21