浅析氨基酸代谢在生物有机化学与化学生物学教学中的重要性
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摘要
从氨基酸代谢的基本内容出发,分析并整理了其在生物化学教学中的意义与教学要点,其中富有的各种生物化学过程也充满了趣味性,对于本科生教学是良好的素材。在举例阐述其多样性、复杂性、趣味性与启发性的基础上,讨论生物化学教学中氨基酸代谢相关内容,是一种将前沿科学融入基础生物化学教育的新探索。
The manuscript starts from fundamental knowledge of amino acid metabolism, followed by the analysis of how and why we incorporate it into current biochemistry education. These metabolic processes containing different biochemical reaction mechanisms are generally fascinating, and thus can be selected as good study materials for undergraduate education to attract their attention. Based on the discussion of various amino acid examples, the significance is demonstrated in different aspects as diversity, complexity, attractivity and inseparability. It is a meaningful trial of installing frontier research into fundamental knowledge to deepen amino acid metabolic contents in biochemistry education.
The manuscript starts from fundamental knowledge of amino acid metabolism, followed by the analysis of how and why we incorporate it into current biochemistry education. These metabolic processes containing different biochemical reaction mechanisms are generally fascinating, and thus can be selected as good study materials for undergraduate education to attract their attention. Based on the discussion of various amino acid examples, the significance is demonstrated in different aspects as diversity, complexity, attractivity and inseparability. It is a meaningful trial of installing frontier research into fundamental knowledge to deepen amino acid metabolic contents in biochemistry education.
引文
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[13]王小生.中国食物与营养, 2005, No. 7, 48.
[14]Sinha, M.; Manna, P.; Sil, P. C. Toxicol. In Vitro 2007, 8, 1419.
[15]潘光亮,欧阳平凯.南京化工学院学报, 1994, No. 2, 33.
[16]张洪渊.生物化学原理.第1版.北京:科学出版社, 2006:144.
[17]王志鹏,张军.化学教育, 2018, 39(4), 72.
[18]王志鹏,袁金颖.化学教育, 2016, 37(12), 4.
[19]王志鹏,张军.化学教育, 2018, 39(2), 78.
[20]王志鹏,王田,马新雨,张军.生命的化学, 2017, 37(6), 946.
[2]全先庆,张渝洁,单雷,毕玉平.生物技术通报, 2007, No. 1, 14.
[3]Wang, Y.; Schnell, B.; Baumann, S.; Müller, R.; Begley, T. P. J. Am. Chem. Soc. 2017, 139, 1742.
[4]王志鹏.大学化学, 2017, 32(6), 86.
[5]王联结.生物化学与分子生物学.第2版.北京:科学出版社, 2004:150.
[6]王镜岩,朱圣庚,徐长发.生物化学.第3版.北京:高等教育出版社, 2002:487.
[7]Riedijk, M. A.; van Beek, R. H.; Voortman, G.; de Bie, H. M.; Dassel, A. C.; van Goudoever, J. B. Am. J. Clin. Nutr. 2007, 86, 1120.
[8]Felig, P. Annu. Rev. Biochem. 1975, 1, 933.
[9]江昌俊,余有本.安徽农业大学学报, 2001, 28(4), 425.
[10]Kilani, R. A.; Cole, F. S.; Bier, D. M. Am. J. Clin. Nutr. 1995, 6, 1218.
[11]张惠清.实用妇幼卫生, 2004, No. 1, 6.
[12]喻唯民,徐力,李晓雯,贺春,沈明,张知新,靳耀英,周忠蜀,乔付.中国医学科学院学报, 2003, 25(2), 218.
[13]王小生.中国食物与营养, 2005, No. 7, 48.
[14]Sinha, M.; Manna, P.; Sil, P. C. Toxicol. In Vitro 2007, 8, 1419.
[15]潘光亮,欧阳平凯.南京化工学院学报, 1994, No. 2, 33.
[16]张洪渊.生物化学原理.第1版.北京:科学出版社, 2006:144.
[17]王志鹏,张军.化学教育, 2018, 39(4), 72.
[18]王志鹏,袁金颖.化学教育, 2016, 37(12), 4.
[19]王志鹏,张军.化学教育, 2018, 39(2), 78.
[20]王志鹏,王田,马新雨,张军.生命的化学, 2017, 37(6), 946.