黄芪桂枝五物汤联合甲钴胺治疗2型糖尿病下肢周围神经病变临床疗效观察
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摘要
目的:黄芪桂枝五物汤联合甲钴胺治疗2型糖尿病下肢周围神经病变患者的疗效观察。方法:选取2015年5月-2017年5月我院收治的60例2型糖尿病下肢周围神经病变患者为研究对象,随机抽取30例为对照组行甲钴胺片治疗,另30例为观察组行黄芪桂枝五物汤联合甲钴胺治疗,比较两组患者的临床疗效。结果:两组临床疗效比较,观察组的治疗有效率为93.3%,高于对照组的80.0%,差异有统计意义(P <0.05);观察组与对照组经治疗后,各项血液流变学指标、运动神经与感觉神经传导速度均优于治疗前,差异有统计学意义(P <0.05),治疗后观察组各项血液流变学指标、运动神经与感觉神经传导速度均优于对照组,差异有统计学意义(P <0.05)。结论:黄芪桂枝五物汤联合甲钴胺治疗2型糖尿病下肢周围神经病变患者,疗效确切,具有临床推广价值。
Objective: To explore the efficacy of the Huangqi Guizhi Wuwu decoction( 黄芪桂枝五物汤) plus mecobalamine on type 2 diabetes mellitus(T2 DM) patients with lower extremity peripheral neuropathy. Methods: 60 T2 DM patients with lower extremity peripheral neuropathy treated from May 2015 to May 2017 in our hospital were selected. The subjects were randomly assigned to the control group and the observation group, 30 cases in each group. Patients took the mecobalamine alone or the Huangqi Guizhi Wuwu decoction plus mecobalamine respectively. Results: The clinical efficiency in the observation group was significantly higher than control group(93.3% VS 80.0%)(P<0.05). After treatment, the hemorheological indicators, MCV and SCV in two groups were significantly better than before(P<0.05). The hemorheological indicators, MCV and SCV in the observation group were significantly better than control group(P<0.05). Conclusion: The Huangqi Guizhi Wuwu decoction plus mecobalamine had an obvious effect on T2 DM patients with lower extremity peripheral neuropathy. It is worthy of clinical promotion.
Objective: To explore the efficacy of the Huangqi Guizhi Wuwu decoction( 黄芪桂枝五物汤) plus mecobalamine on type 2 diabetes mellitus(T2 DM) patients with lower extremity peripheral neuropathy. Methods: 60 T2 DM patients with lower extremity peripheral neuropathy treated from May 2015 to May 2017 in our hospital were selected. The subjects were randomly assigned to the control group and the observation group, 30 cases in each group. Patients took the mecobalamine alone or the Huangqi Guizhi Wuwu decoction plus mecobalamine respectively. Results: The clinical efficiency in the observation group was significantly higher than control group(93.3% VS 80.0%)(P<0.05). After treatment, the hemorheological indicators, MCV and SCV in two groups were significantly better than before(P<0.05). The hemorheological indicators, MCV and SCV in the observation group were significantly better than control group(P<0.05). Conclusion: The Huangqi Guizhi Wuwu decoction plus mecobalamine had an obvious effect on T2 DM patients with lower extremity peripheral neuropathy. It is worthy of clinical promotion.
引文
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[7]陈媛,王俊红,张婷婷,等.气压治疗对2型糖尿病下肢周围神经病变患者神经症状及缺血状态的效果观察[J].解放军医药杂志,2016,28(7):51-54.
[2]靳晓建,弓少萍.黄芪桂枝五物汤治疗糖尿病周围神经病变77例[J].光明中医,2014,29(1):66-67.
[3]周小爱,王丽群.化湿活血汤联合甲钴胺治疗2型糖尿病下肢周围神经病变52例[J].浙江中医杂志,2016,51(4):250.
[4]陈丽兰,伊娜,李慧枝,等.穴位注射联合中药熏洗治疗糖尿病下肢周围神经病变40例[J].广东医学,2013,34(10):1615-1617.
[5]廖红玲,吕彩红,潘宁开,等.甲钴胺治疗糖尿病并发下肢周围神经病变的临床效果观察[J].医学理论与实践,2017,30(16):2385-2386.
[6]杨文强,于炎冰,徐晓利,等.神经减压术联合丹红注射液治疗痛性糖尿病性周围神经病[J].中华神经外科疾病研究杂志,2015,14(5):397-400.
[7]陈媛,王俊红,张婷婷,等.气压治疗对2型糖尿病下肢周围神经病变患者神经症状及缺血状态的效果观察[J].解放军医药杂志,2016,28(7):51-54.