王彦晖治疗消化系统肿瘤用药规律
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摘要
目的:基于中医传承辅助平台软件,分析王彦晖教授治疗消化系统肿瘤的用药规律。方法:收集并筛选王教授于厦门燕来福国医堂治疗消化系统肿瘤病案,录入中医传承辅助平台软件,运用软件集成的数据分析方法,分析王教授治疗消化系统肿瘤的用药规律。结果:筛选出治疗消化系统肿瘤处方672首,分析得出其治疗消化系统肿瘤常用药物包括茯苓、陈皮、姜半夏、莪术、三棱、党参、白术、龙骨、牡蛎等,并演化出4首治疗消化系统肿瘤的新处方。结论:王教授治疗消化系统肿瘤以益气健脾、理气化痰、祛瘀散结为基本大法,扶正祛邪并重,同时根据闽南地区脾虚湿盛的致病特点重视健脾袪湿治法,并兼顾安神、止痛等治法以综合调理患者的机体状态。
Objective:To study the medication rules in the treatment of digestive system neoplasms of professor WANG Yan-hui using the traditional Chinese medicine inheritance support system software(TCMISS,V2.5).Methods:The prescriptions used by professor WANG Yan-hui in treating digestive system neoplasms at the Yan-Lai-Fu Chinese Medicine Clinic were collected as input data into TCMISS and were analyzed by software integration method.Results:Totally of 672 prescriptions were selected according to the collection standard in digestive system neoplasms treatment.It was found that the most frequently used Chinese medicine in these prescriptions including Tuckahoe,Pericarpium Citri Reticulatae,Pinellia Tuber,Rhioxma Curcumae Aeruginosae,Rhizome of Common Burreed,Root of Pilose Asiabell,Rhizome of Largehead Atractylodes,Fossilizid,Oyster Shell,and so on.Furthermore,four new prescriptions for treating digestive system neoplasms were created.Conclusion:The core rules of professor WANG Yan-hui in treating digestive system neoplasms were invigorating spleen and replenishing qi,regulating qi-flowing for eliminating phlegm and dispelling stasis and resolving hard mass,which means that strengthening vital qi and eliminating pathogenic factor are equally emphasized in his prescriptions.Besides,taking into consideration the climate characteristics of the southern Fujian,professor WANG Yan-hui attaches importance to invigorating spleen for eliminating dampness,combining with tranquillization and relieving pain to treating patients comprehensively.
Objective:To study the medication rules in the treatment of digestive system neoplasms of professor WANG Yan-hui using the traditional Chinese medicine inheritance support system software(TCMISS,V2.5).Methods:The prescriptions used by professor WANG Yan-hui in treating digestive system neoplasms at the Yan-Lai-Fu Chinese Medicine Clinic were collected as input data into TCMISS and were analyzed by software integration method.Results:Totally of 672 prescriptions were selected according to the collection standard in digestive system neoplasms treatment.It was found that the most frequently used Chinese medicine in these prescriptions including Tuckahoe,Pericarpium Citri Reticulatae,Pinellia Tuber,Rhioxma Curcumae Aeruginosae,Rhizome of Common Burreed,Root of Pilose Asiabell,Rhizome of Largehead Atractylodes,Fossilizid,Oyster Shell,and so on.Furthermore,four new prescriptions for treating digestive system neoplasms were created.Conclusion:The core rules of professor WANG Yan-hui in treating digestive system neoplasms were invigorating spleen and replenishing qi,regulating qi-flowing for eliminating phlegm and dispelling stasis and resolving hard mass,which means that strengthening vital qi and eliminating pathogenic factor are equally emphasized in his prescriptions.Besides,taking into consideration the climate characteristics of the southern Fujian,professor WANG Yan-hui attaches importance to invigorating spleen for eliminating dampness,combining with tranquillization and relieving pain to treating patients comprehensively.
引文
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[13]Ji X,Huang B,Wang G,et al.The ethnobotanical,phytochemical and pharmacological profile of the genus Pinellia.Fitoterapia,2014,93:1-17
[2]陈海玲,施志明,郑培永.中医药对肿瘤患者生存质量影响的研究概况.中医杂志,2008,49(11):1043-1045
[3]张英,侯炜,林洪生.中医药治疗恶性肿瘤临床研究成果与思考.中医杂志,2014,55(6):523-525
[4]何宽其,奚胜艳,李鹏程,等.王彦晖教授善用重剂治疗癌症学术经验举要.中华中医药杂志,2014,29(7):2240-2242
[5]赖鹏华,王彦晖,李鹏程,等.王彦晖教授从“病理产物”论治肿瘤经验.中华中医药杂志,2014,29(10):3139-3141
[6]卢朋,李健,唐仕欢,等.中医传承辅助系统软件开发与应用.中国实验方剂学杂志,2012,18(9):1-4
[7]唐仕欢,申丹,卢朋,等.中医传承辅助平台应用评述.中华中医药杂志,2015,30(2):329-331
[8]唐仕欢,杨洪军.中医组方用药规律研究进展述评.中国实验方剂学杂志,2013,19(5):359-363
[9]唐仕欢,陈建新,杨洪军,等.基于复杂系统熵聚类方法的中药新药处方发现研究思路.世界科学技术(中医药现代化),2009,11(2):225-228
[10]Xi S,Hong R,Huang J,et al.Effects of Ciji Hua'ai Baosheng granule formula(CHBGF)on life time,pathology,peripheral blood cells of tumor chemotherapy model mouse with H22 hepatoma carcinoma cells.Afr J Tradit Complement Altern Med,2014,11(4):94-100
[11]Chihara G,Maeda Y Y,Hamuro J.Current status and perspectives of immunomodulators of microbial origin.Int J Tissue React,1982,4(3):207-225
[12]Chen M,Wang S,Tan M,et al.Applications of nanoparticles in herbal medicine:zedoary turmeric oil and its active compound betaelemene.Am J Chin Med,2011,39(6):1093-1102
[13]Ji X,Huang B,Wang G,et al.The ethnobotanical,phytochemical and pharmacological profile of the genus Pinellia.Fitoterapia,2014,93:1-17