补阳还五汤加味治疗气虚血瘀型慢性脑供血不足患者的临床效果
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摘要
目的研讨气虚血瘀型慢性脑供血不足(CCCI)患者实施补阳还五汤加味治疗的临床价值。方法选择我院收治于2014年8月至2018年8月的56例气虚血瘀型CCCI患者做课题研究,并以随机抽签模式进行分组,A组(n=28)接受常规基础治疗,B组(n=28)在基础治疗下接受补阳还五汤加味治疗,观察评估两组的用药疗效,同时对两组治疗前后的血清C反应蛋白(CRP)、血流动力学指标进行检测与比较。结果与A组的用药总有效率(78.6%)对比,B组的用药总有效率(96.4%)有明显提升,P<0.05,有统计学意义。治疗前,两组接受血清CRP与血流动力学指标(高切、低切等)检测,检测值对比,P>0.05,无统计学意义;治疗后,B组的血清CRP与血流动力学指标(高切、低切等)较A组均显著改善,P<0.05,有统计学意义。结论对气虚血瘀型CCCI患者使用补阳还五汤加味治疗有确切的用药疗效,并可促进炎性因子清除、改善患者的血流动力学指标,值得推荐。
Objective To study the clinical value of Fuyang Huanwu Decoction modified in patients with chronic cerebral circulatory insufficiency(CCCI) with qi deficiency and blood stasis. Methods Fifty-six patients with CCCI of Qi deficiency and blood stasis type admitted to our hospital from August 2014 to August 2018 were selected as subjects and divided into groups by random lottery. Group A(n=28) received routine basic therapy. The group(n=28) underwent the treatment of Buyang Huanwu Decoction modified under the basic treatmen. To observe and evaluate the therapeutic effect of the two groups, and to detect and compare the serum C-reactive protein(CRP) and hemodynamic indexes before and after treatment. Results Compared with the total effective rate of 78.6% in group A, the total effective rate of group B was significantly increased by 96.4%, P<0.05, which was statistically significant. Before treatment, the two groups received serum CRP and hemodynamic parameters(high cut, low cut, etc.), the test value comparison, P>0.05, no statistical significance;after treatment, group B serum CRP and hemodynamics The indexes(high cut, low cut, etc.) were significantly improved compared with group A, P<0.05, which was statistically significant. Conclusion The modified Buyang Huanwu Decoction has a definite therapeutic effect on CCCI patients with Qi deficiency and blood stasis, and can promote the clearance of inflammatory factors and improve the hemodynamic indexes of patients. It is worth recommending.
Objective To study the clinical value of Fuyang Huanwu Decoction modified in patients with chronic cerebral circulatory insufficiency(CCCI) with qi deficiency and blood stasis. Methods Fifty-six patients with CCCI of Qi deficiency and blood stasis type admitted to our hospital from August 2014 to August 2018 were selected as subjects and divided into groups by random lottery. Group A(n=28) received routine basic therapy. The group(n=28) underwent the treatment of Buyang Huanwu Decoction modified under the basic treatmen. To observe and evaluate the therapeutic effect of the two groups, and to detect and compare the serum C-reactive protein(CRP) and hemodynamic indexes before and after treatment. Results Compared with the total effective rate of 78.6% in group A, the total effective rate of group B was significantly increased by 96.4%, P<0.05, which was statistically significant. Before treatment, the two groups received serum CRP and hemodynamic parameters(high cut, low cut, etc.), the test value comparison, P>0.05, no statistical significance;after treatment, group B serum CRP and hemodynamics The indexes(high cut, low cut, etc.) were significantly improved compared with group A, P<0.05, which was statistically significant. Conclusion The modified Buyang Huanwu Decoction has a definite therapeutic effect on CCCI patients with Qi deficiency and blood stasis, and can promote the clearance of inflammatory factors and improve the hemodynamic indexes of patients. It is worth recommending.
引文
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[2]石磊.补阳还五汤联合尼莫地平治疗慢性脑供血不足的临床疗效及其对血液流变学指标的影响分析[J].临床医学研究与实践,2017,2(4):110-111.
[3]谢军朋,谢桥.中西医结合治疗慢性脑供血不足临床研究[J].光明中医,2017,32(24):3606-3608.
[4]高天辉,曾朝山.补阳还五汤合益气聪明汤治疗慢性脑供血不足疗效分析[J].中医临床研究,2016,8(8):52-53.
[5]钟安朴.补阳还五汤加减结合手术治疗慢性脑供血不足的临床分析[J].齐齐哈尔医学院学报,2013,34(8):1151-1152.
[6]夏子禹,张艳,徐孙江.补阳还五汤干预社区慢性脑供血不足的疗效观察[J].陕西中医,2015,10(12):1573-1574.
[7]张志刚,芮素芳.补阳还五汤对慢性心力衰竭气虚血瘀证患者脑钠肽的影响[J].临床医药文献电子杂志,2015,2(31):6468-6469.
[8]王淑兰.补阳还五汤加减治疗慢性脑供血不足的临床疗效观察[J].临床合理用药杂志,2015,13(15):131-132.
[9]张弛,段小英,蒲小兰.补阳还五汤加减结合手法治疗慢性脑供血不足的临床疗效观察[J].中国全科医学,2012,15(28):3308-3309.
[10]刘玉兵.中西医结合治疗脑供血不足的临床疗效分析[J].中国处方药,2016,14(11):99-100.