某院2016年—2017年主要病原菌的分布及其耐药性分析
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摘要
目的:分析医院2016年和2017年主要病原菌种类的临床分布及其耐药性,为加强医院感染防控和合理使用抗菌药物提供参考。方法:抽取2016年和2017年2年间送检标本资料,分析其细菌阳性标本中对抗菌药物的耐药监测数据。结果:2016年送检的34 100样本中,其中8 606个为阳性标本占25.24%;2017年送检的38 268个样本中,其中9 153个为阳性标本占23.92%;阳性最多的是痰及咽喉拭子标本,其检测阳性率最高的是分泌物标本;检出的主要病原菌为革兰阴性菌(G~-),并分布在ICU、神经外科等科室内,且主要病原菌对常规抗菌药物呈现不同程度的耐药性。结论:应加强相关的监测和管理,以促进抗菌药物合理使用,进而遏制耐药菌的产生和传播。
Objective: To analyze the main pathogenic bacteria, clinical distribution and drug resistance in our hospital from 2016 to 2017, and to provide references for our hospital to strengthen the prevention and controlling of bacterial infection and to use rationally antimicrobial agents. Methods: The data of bacterial resistance monitoring in our hospital from January 2016 to December 2017 were analyzed retrospectively. Results: The sputum and throat swab specimens were the most common specimens in the hospital. The most common pathogens were G-bacteria, and they were mainly distributed in the ICU, neurosurgery and other departments. They showed different levels of resistance to conventional antibiotics. Conclusion: Our hospital should strengthen the relevant monitoring and management to promote the rational usage of antimicrobial agents, so as to stop the generation and spread of drug-resistant bacteria.
Objective: To analyze the main pathogenic bacteria, clinical distribution and drug resistance in our hospital from 2016 to 2017, and to provide references for our hospital to strengthen the prevention and controlling of bacterial infection and to use rationally antimicrobial agents. Methods: The data of bacterial resistance monitoring in our hospital from January 2016 to December 2017 were analyzed retrospectively. Results: The sputum and throat swab specimens were the most common specimens in the hospital. The most common pathogens were G-bacteria, and they were mainly distributed in the ICU, neurosurgery and other departments. They showed different levels of resistance to conventional antibiotics. Conclusion: Our hospital should strengthen the relevant monitoring and management to promote the rational usage of antimicrobial agents, so as to stop the generation and spread of drug-resistant bacteria.
引文
[1] Frieri M, Kumar K, Boutin A.Antibiotic resistance[J]. J Infect Public Health, 2017,10(4):p.369-378.
[2] Fair RJ, Tor Y. Antibiotics and bacterial resistance in the21st century[J]. Perspect Medicin Chem, 2014,(6):25-64.
[3]刘波,张卫红,李松琴,等.提高微生物标本送检率的临床效果评价[J].中国感染控制杂志,2016,(11):862-864.
[4]张佩英.提高痰培养标本质量的研究进展[J].解放军护理杂志,2009,(10):33-35.
[5]徐修礼.近5年医院感染菌群的分布趋势及耐药性分析[J].中华医院感染学杂志,2009,(10):1276-1279.
[6]文细毛.全国医院感染监控网医院感染病原菌分布及变化趋势[J].中华医院感染学杂志,2011,(02):350-355.
[7]吴琳,穆利萍,卢健.2009—2011年我院抗菌药应用与细菌耐药分析[J].中国药师,2013,(01):125-127.
[8]李露池,沈晖,某三级综合医院多重耐药菌临床分布[J].中国感染控制杂志,2014,(04):242-245.
[9]张丽华.第三代头孢菌素的用量与大肠埃希菌、肺炎克雷伯菌耐药相关性分析[J].中国药师,2006(03):260-262.
[10]邵亚娟,乔惠平.医院感染常见细菌分布与耐药性分析[J].中国感染控制杂志,2006,(02):153-156,145.
[2] Fair RJ, Tor Y. Antibiotics and bacterial resistance in the21st century[J]. Perspect Medicin Chem, 2014,(6):25-64.
[3]刘波,张卫红,李松琴,等.提高微生物标本送检率的临床效果评价[J].中国感染控制杂志,2016,(11):862-864.
[4]张佩英.提高痰培养标本质量的研究进展[J].解放军护理杂志,2009,(10):33-35.
[5]徐修礼.近5年医院感染菌群的分布趋势及耐药性分析[J].中华医院感染学杂志,2009,(10):1276-1279.
[6]文细毛.全国医院感染监控网医院感染病原菌分布及变化趋势[J].中华医院感染学杂志,2011,(02):350-355.
[7]吴琳,穆利萍,卢健.2009—2011年我院抗菌药应用与细菌耐药分析[J].中国药师,2013,(01):125-127.
[8]李露池,沈晖,某三级综合医院多重耐药菌临床分布[J].中国感染控制杂志,2014,(04):242-245.
[9]张丽华.第三代头孢菌素的用量与大肠埃希菌、肺炎克雷伯菌耐药相关性分析[J].中国药师,2006(03):260-262.
[10]邵亚娟,乔惠平.医院感染常见细菌分布与耐药性分析[J].中国感染控制杂志,2006,(02):153-156,145.