空气波压力治疗仪对糖尿病下肢动脉病变患者足背经皮氧分压的影响
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摘要
目的探讨空气波压力治疗仪(intermittent pneumatic compression,IPC)对糖尿病下肢动脉病变患者足背经皮氧分压(transcutaneous oxygen pressure,TcPO_2)的影响。方法将80例糖尿病下肢动脉病变患者随机分为观察组40例和对照组40例,2组均给予降糖、降压、降脂,改善循环,营养神经等药物治疗,观察组在此基础上加用IPC治疗。评价治疗前和治疗后14d患者足背TcPO_2和踝肱指数(ankle brachial index,ABI)的变化。结果干预前2组足背TcPO_2差异无统计学意义(P>0.05)。干预后观察组TcPO_2较干预前和对照组增高,差异均有统计学意义(P<0.05)。2组ABI干预前后和组间差异均无统计学意义(P>0.05)。结论 IPC治疗可提高糖尿病下肢动脉病变患者足背TcPO_2,有效改善下肢供血和足部的微循环,从而预防糖尿病足的发生。
Objective To investigate the effect of intermittent pneumatic compression(IPC on transcutaneous oxygen pressure(TcPO2)in dorsum of foot in patients with diabetic lower extremity arterial disease.Methods Eighty diabetic lower extremity arterial disease patients were randomly divided into experimental group(40 cases)and control group(40 cases)according to random number table.Both groups were given glucose-lowering,blood pressure and blood lipid lowering,improving circulation,nutritional neurologic and other drug therapy,and the experimental group was treated with IPC therapy instrument.The changes of TcPO_2 and ankle brachial index(ABI)in dorsum of foot before and 14 days after treatment were evaluated.Results There was no statistically significant difference between the two groups of patients with TcPO_2(P>0.05)before intervention.After intervention,TcPO_2 of the experimental group was higher than the control group,and the difference was statistically significant(P<0.05).There was no significant difference between the two groups with ABI before and after intervention(P>0.05).Conclusion The treatment of IPC can improve TcPO_2 of dorsum of foot in patients with diabetic lower extremity arteriopathy,effectively improve blood supply of lower extremity and microcirculation of foot,and prevent the occurrence of diabetic foot.
Objective To investigate the effect of intermittent pneumatic compression(IPC on transcutaneous oxygen pressure(TcPO2)in dorsum of foot in patients with diabetic lower extremity arterial disease.Methods Eighty diabetic lower extremity arterial disease patients were randomly divided into experimental group(40 cases)and control group(40 cases)according to random number table.Both groups were given glucose-lowering,blood pressure and blood lipid lowering,improving circulation,nutritional neurologic and other drug therapy,and the experimental group was treated with IPC therapy instrument.The changes of TcPO_2 and ankle brachial index(ABI)in dorsum of foot before and 14 days after treatment were evaluated.Results There was no statistically significant difference between the two groups of patients with TcPO_2(P>0.05)before intervention.After intervention,TcPO_2 of the experimental group was higher than the control group,and the difference was statistically significant(P<0.05).There was no significant difference between the two groups with ABI before and after intervention(P>0.05).Conclusion The treatment of IPC can improve TcPO_2 of dorsum of foot in patients with diabetic lower extremity arteriopathy,effectively improve blood supply of lower extremity and microcirculation of foot,and prevent the occurrence of diabetic foot.
引文
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[12]李艳,杨郁文.中药泡足联合足部按摩对糖尿病足足部症状及经皮氧分压改变的效果观察[J].蚌埠医学院学报,2016,41(1):123-126.
[13]张勤颖.浅谈空气波压力治疗仪对2型糖尿病下肢血管病变的影响[J].中国医学创新,2014,11(6):98-100.
[14]李万菊,蒲卉明,李敏,等.空气波压力治疗仪治疗糖尿病下肢血管病变的疗效观察[J].护理研究,2016,30(2):179-181.
[15]郑秋兰,胡晓光,李亚永.2型糖尿病患者踝肱指数影响因素分析[J].河北医科大学学报,2015,36(8):935-938.
[16]李鹏,杨兵全,孙子林.经皮氧分压评价糖尿病下肢动脉病变的应用进展[J].中国糖尿病杂志,2015,23(3):284-286.
[17]李艳,杨郁文.经皮氧分压检查在糖尿病足检查中的应用[J].护理研究,2014,28(4):1374-1374,1375.
[18]徐国玲,颜晓东,玉颜庆.经皮氧分压和踝肱指数测定对糖尿病足下肢动脉病变诊断的意义[J].中国临床新医学,2017,10(8):743-747.
[19]陈丽叶,成金罗,叶新华,等.经皮氧分压测定在2型糖尿病周围神经病变中的临床应用价值[J].现代诊断与治疗,2015,26(24):5686-5687.
[20]叶林芳,郑红英,巫丽萍.2型糖尿病患者经皮氧分压测定结果观察及影响因素分析[J].临床护理杂志,2016,15(6):16-19.
[2]陈静娴,叶山东,陈若平,等.2型糖尿病患者下肢动脉病变的相关因素分析[J].中国糖尿病杂志,2016,24(8):697-700.
[3]刘晓蓉,朱德发.糖尿病下肢动脉病变的诊断与治疗[J].国际内分泌代谢杂志,2015,35(5):327-331.
[4]彭青.应用经皮氧分压测试检查糖尿病足的研究进展[J].糖尿病新世界,2017,10(19):196-198.
[5]Pardo M,Alcaraz M,Bernal FL,et al.Transcutaneous oxygen tension measurements following peripheral transluminal angioplasty procedure has more specificity and sensitivity than ankle brachial index[J].Br J Radiol,2015,88(1046):20140571.
[6]王华,胡晶,王晓芳.空气循环压力治疗仪治疗糖尿病下肢血管病变的疗效观察[J].中国卫生标准管理,2014,5(4):25-26.
[7]McDermott MM,Kibbe MR.Improving lower extremity functioning in peripheral artery disease:exercise,endovascular revascularization,or both?[J].JAMA,2017,317(7):689-690.
[8]中华医学会糖尿病学分会.中国2型糖尿病防治指南(2017年版)[J].中华糖尿病杂志,2018,10(1):4-67.
[9]Yang SL,Zhu LY,Han R,et al.Pathophysiology of peripheral arterial disease in diabetes mellitus[J].J Diabetes,2017,9(2):133-140.
[10]Mirault T,Galloula A,Cambou JP,et al.Impact of betablockers on general and local outcome in patients hospitalized for lower extremity peripheral artery disease:The COPART Registry[J].Medicine(Baltimore),2017,96(5):e5916.
[11]周祥群,陈海金,彭兴,等.2型糖尿病合并下肢动脉病变患者的风险因素分析[J].微循环学杂志,2017,27(4):60-62,67.
[12]李艳,杨郁文.中药泡足联合足部按摩对糖尿病足足部症状及经皮氧分压改变的效果观察[J].蚌埠医学院学报,2016,41(1):123-126.
[13]张勤颖.浅谈空气波压力治疗仪对2型糖尿病下肢血管病变的影响[J].中国医学创新,2014,11(6):98-100.
[14]李万菊,蒲卉明,李敏,等.空气波压力治疗仪治疗糖尿病下肢血管病变的疗效观察[J].护理研究,2016,30(2):179-181.
[15]郑秋兰,胡晓光,李亚永.2型糖尿病患者踝肱指数影响因素分析[J].河北医科大学学报,2015,36(8):935-938.
[16]李鹏,杨兵全,孙子林.经皮氧分压评价糖尿病下肢动脉病变的应用进展[J].中国糖尿病杂志,2015,23(3):284-286.
[17]李艳,杨郁文.经皮氧分压检查在糖尿病足检查中的应用[J].护理研究,2014,28(4):1374-1374,1375.
[18]徐国玲,颜晓东,玉颜庆.经皮氧分压和踝肱指数测定对糖尿病足下肢动脉病变诊断的意义[J].中国临床新医学,2017,10(8):743-747.
[19]陈丽叶,成金罗,叶新华,等.经皮氧分压测定在2型糖尿病周围神经病变中的临床应用价值[J].现代诊断与治疗,2015,26(24):5686-5687.
[20]叶林芳,郑红英,巫丽萍.2型糖尿病患者经皮氧分压测定结果观察及影响因素分析[J].临床护理杂志,2016,15(6):16-19.