二硫化钼纳米片基纳米团簇的制备及其在近红外激光的热转换性能
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摘要
探讨了γ-聚谷氨酸(γ-PGA)介导合成γ-PGA/二硫化钼(MoS_2)纳米团簇的可行性,分析了γ-PGA/MoS_2纳米团簇在近红外激光的热转换性能。将γ-PGA和合成MoS_2纳米片的前驱体四硫代钼酸铵同时溶解于蒸馏水中,通过水热法自下而上一步合成出了γ-PGA修饰的MoS_2纳米团簇,MoS_2纳米团簇的直径为(197.3±26.6)nm。团簇结构的形成可能与Mo~(4+)离子和γ-PGA链中羧基上氧原子的配位作用有关。在水热反应过程中,由于这种配位作用的存在,生成的MoS_2纳米片可能进一步以γ-PGA分子链中氧原子为中心形成团簇。该纳米团簇具有优异的胶体稳定性、光热转换性能(质量消光系数为11.23L·g~(-1)·cm~(-1))和细胞相容性,有望在肿瘤的光热治疗等领域得到应用。
The feasibility ofγ-PGA/MoS_2 nanocluster synthesized with the assistance ofγ-poly glutamic acid(γ-PGA)is discussed.Thermal conversion performance ofγ-PGA/MoS_2 nanocluster under near-infrared laser is analyzed.γ-PGA and(NH_4)_2MoS4 which is the precursor of MoS_2 nanosheet are dissolved into distilled water,andγ-PGA modified MoS_2 nanocluster is synthesized from bottom to top with hydrothermal method.The diameter of nanocluster is(197.3±26.6)nm.Nanocluster configuration may be relevant to the coordination between Mo~(4+) ion and oxygen atom belonging to the carboxyl group ofγ-PGA.During the hydrothermal reaction process,generated MoS_2 nanosheets may form clusters due to the existence of coordination,and the oxygen atoms inγ-PGA molecular chain are the center.Nanoclusters show excellent colloidal stability,photothermal conversion performance(with mass extinction coefficient of 11.23L·g~(-1)·cm~(-1))and admirable cytocompatibility,and they are expected to be applied to the field of photothermal therapy for tumor.
The feasibility ofγ-PGA/MoS_2 nanocluster synthesized with the assistance ofγ-poly glutamic acid(γ-PGA)is discussed.Thermal conversion performance ofγ-PGA/MoS_2 nanocluster under near-infrared laser is analyzed.γ-PGA and(NH_4)_2MoS4 which is the precursor of MoS_2 nanosheet are dissolved into distilled water,andγ-PGA modified MoS_2 nanocluster is synthesized from bottom to top with hydrothermal method.The diameter of nanocluster is(197.3±26.6)nm.Nanocluster configuration may be relevant to the coordination between Mo~(4+) ion and oxygen atom belonging to the carboxyl group ofγ-PGA.During the hydrothermal reaction process,generated MoS_2 nanosheets may form clusters due to the existence of coordination,and the oxygen atoms inγ-PGA molecular chain are the center.Nanoclusters show excellent colloidal stability,photothermal conversion performance(with mass extinction coefficient of 11.23L·g~(-1)·cm~(-1))and admirable cytocompatibility,and they are expected to be applied to the field of photothermal therapy for tumor.
引文
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