不同MRI序列对膝关节软骨损伤诊断敏感度及特异度分析
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摘要
目的探讨分析不同MRI序列对膝关节软骨损伤诊断敏感度及特异度。方法选择我院收治的膝关节软骨损伤患者75例,对患者分别进行MRI常规序列以及T_2-mapping序列检查,关节镜检查结果作为金标准,分析不同MRI检查序列对膝关节软骨损伤诊断情况。结果 275例患者共375个关节软骨行常规MRI序列扫描以及关节镜诊断,常规RMI序列与关节镜分级一致性为0.638,表明MRI常规扫描与关节镜分级之间具有一定的一致性。T_2-mapping序列与关节镜分级一致性为0.816,表明MRI常规扫描与关节镜分级之间具有良好的一致性。MRI常规扫描诊断灵敏度为59.85%,诊断特异度为96.71%,T_2-mapping序列扫描诊断灵敏度为75.00%,诊断特异度为98.77%,T_2-mapping序列扫描诊断灵敏度显著高于MRI常规扫描(P<0.05),T_2-mapping序列扫描与MRI常规扫描特异度无明显差异(P>0.05)。结论 T_2-mapping序列扫描对膝关节软骨损伤诊断分级更为准确,且诊断敏感度较常规MRI更高。
引文
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[18] Schleich C,Bittersohl B,Miese F,et al.Glycosaminoglycan chemical exchange saturation transfer at 3T MRI in asymptomatic knee joints [J].Acta Radiologica,2016,57(5):627-631.
[2] 肇刚,刘玉杰,曲峰,等.三维脂肪抑制快速扰相梯度回波序列在单间室骨关节炎单髁置换术前评估中的价值[J].中华外科杂志,2015,53(7):528-532.
[3] Hongsheng W,Koff MF,Potter HG,et al.An MRI-compatible loading device to assess knee joint cartilage deformation:effect of preloading and inter-test repeatability [J].Journal of Biomechanics,2015,48(12):2934-2940.
[4] 满玉琳,郭佑民,杨静,等.低场磁共振对膝关节软骨损伤评价的Meta分析[J].影像技术,2017,29(2):49-50.
[5] 苗宝娟,刘广红,娄晓宇.磁共振对膝关节软骨损伤分级诊断的研究价值[J].中国CT和MRI杂志,2015,13(6):98-100.
[6] 李兰,罗文军,殷富春,等.MRI三维扰相梯度回波序列在膝关节软骨损伤中的诊断价值[J].中国CT和MRI杂志,2015,13(11):118-120.
[7] Olender G,Hurschler C,Fleischer B,et al.Validation of an anatomical coordinate system for clinical evaluation of the knee joint in upright and closed MRI [J].Annals of Biomedical Engineering,2014,42(5):1133-1142.
[8] 袁春兰.膝关节软骨损伤的MRI与关节镜诊断[J].河南医学研究,2017,26(4):695-696.
[9] Hongsheng W,Koff MF,Potter HG,et al.An MRI-compatible loading device to assess knee joint cartilage deformation:effect of preloading and inter-test repeatability [J].Journal of Biomechanics,2015,48(12):2934-2940.
[10] 梁智锋,蓝燚锋,黄钰坚.3D-FS-SPGR序列在膝关节软骨损伤诊断中的应用价值[J].现代医用影像学,2017,26(4):1014-1016.
[11] Wang X,Blizzard L,Halliday A,et al.Association between MRI-detected knee joint regional effusion-synovitis and structural changes in older adults:a cohort study [J].Annals of the Rheumatic Diseases,2014,75(3):519-522.
[12] Rsnen LP,Tanska P,Mononen ME,et al.Spatial variation of fixed charge density in knee joint cartilage from sodium MRI-implication on knee joint mechanics under static loading [J].Journal of Biomechanics,2016,49(14):3387-3396.
[13] 于秀英,韩广,何勇.MRI水脂分离序列成像对膝关节半月板损伤的诊断价值[J].中国中西医结合影像学杂志,2016,14(5):530-533.
[14] Karvonengutierrez CA,Harlow SD,Jacobson J,et al.The relationship between longitudinal serum leptin measures and measures of magnetic resonance imaging-assessed knee joint damage in a population of mid-life women [J].Annals of the Rheumatic Diseases,2014,73(5):883-887.
[15] 李振玉.膝关节软骨损伤的MRI诊断与关节镜相关性研究[J].中国卫生标准管理,2016,7(15):168-170.
[16] 张振勇,王海波,段宏伟.磁共振对膝关节软骨损伤的诊断价值[J].中国CT和MRI杂志,2015,13(7):106-109.
[17] 樊子健,吴丽萍,任有忠,等.3.0T磁共振T2-Mapping、3D-FSE-Cube与常规序列对膝关节软骨损伤分级对比分析[J].磁共振成像,2017,8(9):675-680.
[18] Schleich C,Bittersohl B,Miese F,et al.Glycosaminoglycan chemical exchange saturation transfer at 3T MRI in asymptomatic knee joints [J].Acta Radiologica,2016,57(5):627-631.