用户名: 密码: 验证码:
一种实时的跌倒姿态检测和心率监护系统的研究
详细信息    本馆镜像全文|  推荐本文 |  |   获取CNKI官网全文
摘要
近年来,人体在跌倒状态下相关心率波动变化的研究已逐渐成为生物医学工程界一个热门的课题。其中一个具有重要研究价值的领域是针对常见的老人跌倒导致的健康危害的控制技术,即基于心率和跌倒姿态系统的课题研究。另一方面,无线躯体传感器及其网络技术由于其低功耗、移动性强、安全性高、集成微型化等特点也成为近年来人体医疗监护系统的研究热点。因此,本文提出了基于无线躯体传感器网络的人体跌倒状态及心率检测系统,构建的系统能在短时间内对病人或者老人在跌倒现象下心率变异这一生理参数进行实时性跟踪,实现早期报警。
     本文首先构建了便于穿戴的跌倒检测单元、心率检测单元以及无线PDA系统平台,将跌倒现象和突发性心脏疾病有机联系起来分析,该平台也为其它生理监护提供了良好的扩展性。
     其次,介绍了人体跌倒识别的研究背景、意义及现状。针对老年人跌倒现象,文中通过实验采集多种不同跌倒模式的特征数据,提出了基于支持向量机(SVM)的跌倒模式识别二分类方法,取得了很好的诊断效果。而针对诊断过程中特征向量维数过多而导致运算复杂度高和存储消耗量大等问题,文中采用成分分析(PCA)做降维处理,降低了识别算法的运算复杂度,进一步提高了系统性能。
     文中还在现有的心电信号(ECG)处理技术研究基础上,针对两电极检测出的ECG信号容易受到皮肤移动、肌电伪迹等干扰问题,本文采用小波变换对心电信号进行了消噪预处理,同时也提出了基于最小包围圆的投票表决方法统计心率值,最大程度地捕捉周期性表现的R-R间期,取得了满意的结果。文中还详细分析了MIT-BIH数据库中的心律失常心电数据。实验结果表明,该方法可以准确地提取出心率值。
     对于人体健康状态动态监控问题,文中运用无线躯体传感器网络技术实时实地监控人体活动生理状态。文中还针对人体医疗监护特点,基于Energy~*Delay模型的蚁群算法。算法中人工蚂蚁通过在线延迟的方式进行数据交换,并收集邻居节点状态和网络路由信息,以此建立起最佳路由表,使每次传输固定大小的数据和消耗相同能量的情况下使数据包传输时延最小。由于在无线通信系统中,能量消耗和传输时延是两个相互对立特征量,在此运用加强学习的方法RL(Reinforcement Learning)来训练该模型,取得了满意的效果。
     本文最后讨论了系统在人体跌倒监护中的应用。通过具体实验方法,对普通性跌倒现象进行了报警试验,取得了90%以上的跌倒报警正确率,并且实时地检测包括跌倒过程在内的所有人体跌倒状态下心率的波动情况,取得了初步的实验效果。
Now people pay more attention to their safety and health while staying in physical activity status, and especially focus on falling which happens on the elderly. And with the development of microelectronics and weak signals detection technique, the research based on integrated systems of heart rete and falling models has already become an important topic as a research direction of biomedical engineering. At the same time, wireless body sensor network technology is being developed as a research hotspot of health monitoring while movements with such the characteristics as energy saving, ad hoc, safety, integration and micromation. The main contents include:
     The thesis first introduces the current research status of integration system based on heart rate and falling. After analyzing the virtue and shortcoming of current falling recognition theories, the paper summarizes the heart rate detection while falling and places an emphasis on the most efficient method by detection of R-R periods in two-electrode ECG signals. Chapter 2 introduces the structure and contents of system platform considering the micromation, low power, wearable, high reliability and safety. And then the principle, design methods and corresponding signals extraction technology of each module of the system. Considering the artifical singals such as skin dithering and EMG, the wavelet transform algorithm is employed to extract the QRS waves from the polluted ECG singal, and voting algorithm based on the smallest circle is also brought forward to remove the noises. Several experiments were conducted to give evidence of the robustness and accuracy of the proposed algorithms. For falling phenomenons of the elderly, Chapter 4 discussed the recoginiton technique of plenty of falling models and employed Support Vector Machine (SVM) to binary-classify the models of different activities and recognize falling events. As the shortcoming of complexity and huge memory requirement brought by characteristic vetctors, we used Primary Component Analysis (PCA) to reduce dimensions of vectors space. In the experiment, seven falling patterns were implemented to evaluate the method and obtained satisfying results.
     For real-time health monitoring, wireless technology was employed to transfer biomedical data. So all the physiological phenomenons can be synchronized and tracked by wireless body sensor networks. Chapter 5 introduced one network topology suitable for body area, and enhanced the communication protocols including Secuirity and transport layers. Considering a wireless sensor network where the nodes have limited energy, we propose a novel model Energy*Delay based on ant algorithms (E&D ANTS) to minimize time delay in transferring a fixed number of data packets in an energy-constrained manner in one round. However, because of the tradeoff of energy and delay in wireless network systems, the Reinforcement Learning (RL) algorithm is introduced to train the model. The simulation results show that our method performs about seven times better than AntNet and than AntChain by about 150 percent in terms of energy cost and delay per round.
     Finally, the thesis discussed some applications about falling monitoring. Many experimental researches of heart rate and falling recongnition are finished, And the ninety percent early-warning ratio are successfully obtained. At the same time, we can track and monitor realtime heart-rate fluctuation curves while subjects move. The primary trial proved successful and effective.
引文
1.Rintala PE, Pukkala E, Paakkulainen HT, et al.Self-experienced physical workload and risk of breast cancer [J].ScandJ Work Environ Health,2002,28(3):158-162.
    2.Wyshak G, Frisch RE.Breast cancer among former college athletes compared to nonathletes: a 15 year follow-up [J].Br J Cancer, 2000, 82 (3):726-730.
    3.高炳宏,陈佩杰,李之俊.运动与心率变异性[J].中国运动医学杂志.2003,22(5): 490-492.
    4.赵敬国.增量运动过程中心率变异性的研究[J].山东体育科技,1997,19(3): 32-35.
    5.V.Vuksanovic, G.Vera, and K.Jasna, et al.Effect of posture on heart rate variability spectral measures in children and young adults with heart disease [J].Internatioal Journal of Cardiology, 2005; 101(2):273-278.
    6.C.Falcone, M.P.Empana, and C.Klersy, et al.Rapid Heart Rate Increase at Onset of Exercise Predicts Adverse Cardiac Events in Patients With Coronary Artery Disease [J].Circulation.2005, 112:1959-1964.
    7.X.Jouven, J.P.Empana, and P.Schwartz, et al.Heart-rate profile during exercise as a predictor of sudden death[J].NEngl JMed.2005, 352:1951-1958.
    8.Matthews CE, Shu XO, J in F, et al.Lifetime physical activity and breast cancer risk in the ShanghaiBreast Cancer Study [J].Br J Cancer,2001,84(7):994-1001.
    9 M.N.Nyan, F.E.H Tay, A.W.Y Tan,et.al.Distinguishing fall activities from normal activities by angular rate characteristics and high-speed camera characterization [J].Medical Engineering & Physics, 2006, 28:842-849.
    10.覃朝晖,于普林,乌正赉.老年人跌倒研究的现状及进展[J].中华老年医学杂志.2005,24:711-714.
    11.周白瑜,于普林.老年人跌倒和心血管疾病[J].中华老年医学杂志.2006,25(3): 224-227.
    12.M.N.Nyan, F.E.H Tay, A.W.Y Tan,et.al.Distinguishing fall activities from normal activities by angular rate characteristics and high-speed camera characterization [J].Medical Engineering & Physics, 2006, 28:842-849.
    13.Chang JT, Morton SC, Rubenstein LZ, et al.Interventions for the prevention of falls in older adults: systematic review and meta-analysis of randomized clinical trials[J].BMJ, 2004,328:680-683.
    14.Gillespie LD, Gillespie WJ, Robertson MC, et al.Interventions for preventing falls in elderly people [J].Cochrane Database Syst Rev.2003, 4:CD000340.
    15.龚光红,冯勤,彭晓源等.人体运动的形象化建模与仿真[J].系统仿真学报.2002;14(3):285-287.
    16.吴威,隋爱娜,周忠.分布式虚拟环境中虚拟人运动的表示[J].系统仿真学报.2000;12(4):327-329.
    17.李林涛,王声涌.老年跌倒的疾病负担与危险因素[J].中华流行病学杂志.2001;22:262-264.
    18.Najafi B, Aminian K, Loew F, Blanc Y, Robert Ph.Measurement of stand-sit and sit-standtransitions using a miniature gyroscope and its application in fall risk evaluation in theelderly [J].IEEE TransBiomed Eng 2002; 49(8):843-851.
    19.Najafi B, Aminian K, Paraschiv-Ionescu A, Loew F, Bula C, RobertPh.Ambulatory system for human motion analysis using a kinematic sensor [J].IEEE Trans Biomed Eng 2003; 50(6):711-723.
    20.Aminian K, Robert Ph, Buchser EE, et al.Physical activity monitoring based on accelerometry:validation and comparison with video observation [J].Med Biol Eng Comput 1999; 37(3):1-5.
    21.Veltink PH, Bussmann HBJ, de Vries W, et al.Detection of static and dynamic activitiesusing uniaxial accelerometers [J].IEEE Trans Biomed Eng 1996; 4(4):375-85.
    22.Bussmann JBJ, van de Laar YM, Neeleman MP, et al.Ambulatory accelerometry to quantifymotor behavior in patients after failed back surgery: a validation study [J].Pain 1998;74:153-161.
    23.Ng J, Sahakian AV, Swiryn S.Sensing and documentation of body position duringambulatory ECG monitoring [J].Comput Cardiol 2000;27:77-80.
    24.Maarit Kangas, Antti Konttila, Ilkka Winblad, et al.Determination of simple thresholds foraccelerometry-based parameters for fall detection [C].//Proceedings of the 29th AnnualInternational Conference of the IEEE EMBS, Lyon, France.August 2007.pp.1367-1370
    25.K.Doughty, R.Lewis, and A.McIntosh.The design of a practical and reliable fall detectorfor community and institutional telecare [J].J.Telemed.Telecare, 2000; 6, Suppl.1, pp.S150-154.
    26.S.Brownsell and M.S.Hawley.Tomatic fall detectors and the fear of falling.J.Telemed.Telecare [J].2004; 10:262-266.
    27.T.Yoshida, F.Mizuno, T.Hayasaka, et al.A wearable computer system for a detection andprevention of elderly users from falling [C].//In IFMBE Proc., 2005, vol.12.
    28.M.J.Mathie, A.C.F.Coster,B.G.Celler, and N.H.Lovell.Classification of basic dailymovements using a triaxial accelerometer [J].Med.Biol.Eng.Comput., 2004; 42:670-687.
    29.M.J.Mathie.Monitoring and Interpreting Human Movement Patterns Using a TriaxialAccelerometer.Ph.D.thesis, Univ.New South Wales, Sydney, Australia, 2003.
    30.A.H.Khandoker, D.Lai and R.K.Begg, et al.A Wavelet-Based Approach for Screening Falls Risk in the Elderly using Support Vector Machines [C].//Proceedings of the 4th ICISIP'06, 2006,15:184-189.
    31.P.M.Mahoudeaux et al,Simple microprocessor-based system for on-line ECG analysis [J],Med.Biol.Eng.Cornput.,1981;19:497-500.
    32.LANDER P.and BERBARI E.Time-frequency plane Wiener filtering of the high resolution ECG: Development and application [J].IEEE Transaction on Biomedical Engineering.1997,44:256-265.
    33.THAKOR N V and ZHU Y S.Application of adaptive filtering to ECG analysis: Noise callcellation and arrhythmia detection [J].IEEE Transation on Biomedical Engineering.1991, 38:785-794.
    34.F.E.M.Brekelmans,C.D.R.de vaal, A QRS Detection Scheme for Mulitchannel ECG Devices [J].Computers In Cardiology, 1981:437-441.
    35.CHRISTOVI, IVAYLO I.and DASKALOV K.Filtering of electromyogram artifacts from the electrocardiogram [J].Medical Engineering & Physics.1999, 21:731-736.
    36.LANDER P.and BERBARI E.Time-frequency plane Wiener filtering of the high resolution ECG: Development and application [J].IEEE Transaction on Biomedical Engineering.1997,44:256-265.
    37.THAKOR N V and ZHU Y S.Application of adaptive filtering to ECG analysis: Noise callcellation and arrhythmia detection [J].IEEE Transation on Biomedical Engineering.1991, 38:785-794.
    38.Chouakri and Sid Ahmed.Level-dependent wavelet denoising: Application to very noisy ECG signals[C]//IWSSIP2005—12th International Workshop on Systems, Signals and Image Processing(SSIP-SPI, 2005).Chalkida, Greece, 2005,9:95-99.
    39.孙光耀,余生晨.小波变换在QRS波检测中的应用[J].北方工业大学学报,2003, 15(3):15-17.
    40.陈文菊,潘敏,赵治栋,等.基于小波分析和Hilbert变换的R波检测算法[J].传感技术学报,2006, 19(1): 148-252.
    41.J.Pan, W.J Tompkins.A Real-Time QRS Detection Algorithm [J], Trans.Biomed, Eng., 1985,32(3):230-236.
    42.王磊,郑崇勋,叶继伦等,一种高效的QRS波实时检测方法[J],北京生物医学工程.1998, 17(4): 217-222.
    43.S.A.Coast,R.M.Stem,et.al., An Approach to Cardiac Arrhythmia Analysis Using Hidden Markov Modele [J], IEEE Trans.Biomed,Eng.1990, 37(9): 826-835.
    44.Guang-zhong Yang.Body Sensor Network.Springer Press.2006.
    45.LIN Y H, JAN I C KO, CHEN Y Y, et al.A wireless PDA based physiological monitoring system for patient transport [J].IEEE Transactions on Information Technology in Biomedicine, 2004,8(4): 439- 447.
    46. HEINZELMAN W B, CHANDRAKASAN A P, BALAKRISHNAN H. Energy-efficient communication protocol for wireless microsensor networks[C], Proceedings of HICSS 2000, Hawaii: IEEE press, 2000:3005-3014.
    47. HEINZELMAN W B, CHANDRAKASAN A P, BALAKRISHNAN H. An application-specific protocol architecture for wireless microsensor networks [J], IEEE Trans. on Wireless Communications, 1(4):660-670.
    48. LINDSEY S, RAGHAVENDRA C, SIVALINGAM K M. Data gathering algorithms in sensor networks using energy metrics [J]. IEEE Transactions on parallel and Distributed Systems, 2002,13(9):924-935.
    49. Di CARO G, DORIGO M. Antnet: a mobile agents approach to adaptive routing[R]. Belgium: Universite Libre de Bruxelles, 1997.
    50. Benjamin EJ, Wolf PA, D'Agostino RB, Silbershatz H, Kannel WB, Levy D.Impact of atrial fibrillation on the risk of death: the Framingham heart study [J].Circulation 1998; 98(10):946-952.
    51. S. Akselrod, D. Gordon, F.A. Ubel, et al. Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control [J], Science 213 .1981:220-222.
    52. M. Pagani, F. Lombardi, S. Guzzetti, et al. Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog [J], Circ. Res 1986; 59:178-193.
    53. Emil Jovanov, Aleksandar Milenkovic, Chris Otto, Piet C de Groen. A wireless body area network of intelligent motion sensors for computer assisted physical rehabilitation [J]. Journal of NeuroEngineering and Rehabilitation. 2005,2(1):6.
    54. Aminian K, Robert Ph, Buchser EE, et al. Physical activity monitoring based on accelerometry:validation and comparison with video observation [J]. Med Biol Eng Comput 1999; 37(3):1-5.
    55. MSP430FG439. http://focus.ti.com/docs/prod/folders/print/msp430fg439.html.
    56. M. J. Mathie, A. C. F. Coster,B.G.Celler, and N. H. Lovell. Classification of basic daily movements using a triaxial accelerometer [J]. Med. Biol. Eng. Comput., 2004; 42:670-687.
    57. Maarit Kangas, Antti Konttila, Ilkka Winblad, et al. Determination of simple thresholds for accelerometry-based parameters for fall detection [C]. //Proceedings of the 29th Annual International Conference of the IEEE EMBS, Lyon, France. August 2007. pp.1367-1370
    58. K. Kiani, C J. Snijders and E.S. Gelsema. Computerized analysis of daily life motor activity for ambulatory monitoring [J]. Technology and Health Care, 1997;5(4):307-318.
    59. K. Aminian, P. Robert, E.E. Buchser, B. Rutschmann, D. Hayoz and M. Depairon. Physical activity monitoring based on accelerometry: validation and comparison with video observation [J]. Medical and Biological Engineering and Computing, 1999;37(3):304-308.
    60.J.Fahrenberg, F.Foerster,M.Smeja and W.Muller.Assement of posture and motion by multichannel piezoresistive accelerometer recordings [J].Psychophysiology.1997;34(5):607-612.
    61.K.M.Kerr, J.A.White, D.A.Barr, and R.A.Mollan.Standardisation and definitions of the sit-stand-sit movement cycle [J].Gait and Posture, 1994; 2(3):182-190.
    62.K.M.Kerr, J.A.White, D.A.Barr, and R.A.Mollan/ Ama;usos pf the sit-stand-sit movement cycle in normal subjects [J].Clinical Biomechanics, 1997;12(4):236-245.
    63.B.J.Munro, J.R.Steele, G.M.Bashford, M.Ryan, and N.Britten.A kinematic and kinetic analysis of the sit-to-stand transfer using an ejector chair: Implications for elderly rheumatoid arthritic patients [J].Journal of Biomechanics.1998,31(3):263-271.
    64.M.J.Mathie.Monitoring and Interpreting Hman Movement Patterns Using a Triaxial Accelerometer.Ph.D.thesis, Univ.New South Wales, Sydney, Australia,2003.
    65.S.R.Lord, J.A.Ward, P.Williams and K.J.Anstey.Anepidemiological study of falls in older community-dwelling women: the Randwick falls and fratures study [J].Australian Journal of Public Health.1993;17(3):240-245.
    66.Jackson J.E.A User's Guide to Principal Components.New York: John Wiley, 1991.
    67.李荣雨.基于PCA的统计过程监控研究[博士论文].浙江:浙江大学.2007.
    68.边肇祺,张学工等.模式识别.北京:清华大学出版社,2000.
    69.Vapnik V著,张学工译.统计学习的理论本质.清华大学出版社,2000.
    70.赵治栋,潘敏,李光,陈裕泉.ICA及其消除心电信号中肌电伪迹的应用[J].浙江大学学报(工学版).2004,38(1): 103-107.
    71.S.Mallat.A theory for multiresolution signal decomposition:the wavelet representation.IEEE Trans.on PAMI, 1989, 11(7): 674-693.
    72.余辉,张力新,刘文耀等.基于小波的数据挖掘技术在Holter心电信号分析中的应用[J].天津大学学报.2006;39(6): 153-56.
    73.季虎,毛玲,孙即祥.基于小波变换与形态元算的R波检测算法[J].计算机应用.2006;26(5):1223-1225.
    74.Behrooz Parhami.Voting Algorithms [J].IEEE Transactions on Reliability.1994.43(4):617-629.
    75.Federica Ricca and Bruno Simeone.Local search algorithms for political districting [J].European Journal of Operational Research.2008, 189(3): 1409-1426.
    76.Lin X, Yacoub S, Burns J, Simske S.Performance analysis of pattern classifier combination by plurality voting [J].Pattern Recognition Letters, 2003, 24(12):1959-1969.
    77.Huang HP, Liu YH.Fuzzy support vector machines for pattern recognition and data mining [J].Int'l Journal of Fuzzy Systems, 2002, 4(3):826-835.
    78.David MJ, Robert PW.Support vector domain description [J].Pattern Recognition Letters, 1999,20:1191-1199.
    79.B.Parhami.Voting algorithm [J].IEEE Transactions on Reliability.1994, 43(4):617-629.
    80.徐国栋,骆清铭.老年人运动中跌倒的病因分析与预防[J].武汉体育学院学报.2000,34(4):48-51.
    81.C.V.Bouten, K.T.Koekkoek, M.Verduin, R.Kodde, and J.D.Janssen.A triaxial accelerometer and portable data processing unit for the assessment of daily physical activity [J].IEEE Transactions on Biomedical Engineering.1997; 44(3):136-147.
    82.A.H.Khandoker, D.Lai and R.K.Begg, et al.A Wavelet-Based Approach for Screening Falls Risk in the Elderly using Support Vector Machines [C].//Proceedings of the 4th ICISIP'06, 2006,15:184-189.
    83.P.H.Veltink, H.B.Bussmann, W.D.Vries, Martens and R.C.van Lummel.Detection of static and dynamic activities using uniaxial accelerometers [J].IEEE Transactions on Rehabilitation Engineering.1996;4(4):375-385.
    84.G.Williams, K.Doughty, K.Cameron, and D.A.Bradley.Asmart fall and activity monitor for telecare applications [J].//In Proceeedings of the 20~(th) Annual International Conference of the IEEE Engineering in Medicine and Biology Society, volume 20, pages 1151-1153.IEEE,1998.
    85.Guolin, S., Jie, C., Wei, G.and Liu, K.J.R., Signal processing techniques in network-aided positioning: a survey of state-of-the-art positioning designs[J].IEEE Signal Processing Magazine.2005, 22(4):12-23.
    86.A.H.Sayed, A.Tarighat, and N.Khajehnouri, Network-based wireless location: challenges faced in developing techniques for accurate wireless location information[J].IEEE Signal Processing Magazine.2005, 22(4):24-40.
    87.Gustafsson, F.and Gunnarsson, F., Mobile positioning using wireless networks: possibilities and fundamental limitations based on available wireless network measurements[J].IEEE Signal Processing Magazine.2005, 22(4):41-53.
    88.Grubb BP, Kosinski D, Tilt table testing: concepts and limitations [J].PACE,1997,20:781-787.
    89.王煜,李软炜,邓洁.心率变异分析与心血管疾病[J].医学研究杂志.2008,37(2):11-13.
    90.Singer DH, Martin GL, magid N, et al.Low HRV and sudden cardiac death [J].J Electrocardiol, 1988,21:S46.
    91.度焱,陶红,朱铨英.心率变异性研究进展[J].国外医学·生理,病理科学与临床分册.2001,21(4): 306-308.
    92.李梅,郑林林,徐岩.心率变异与冠心病的相关性分析[J].实用心电学杂志,2006,15(1):32-33.
    93.范丽凤,陆菊明,郑亚光,等.老年糖尿病患者跌倒及其危险因素[J].中国实用内科学,2004,24(7):399-402.
    94.周金贵,赵施竹.老年高血压病患者运动血压和心率变异分析[J].医学研究杂志.2006,35(2): 38-40.
    95.L.Roelens, S.V.den Bulcke, W.Joseph, G.Vermeeren, and L.Martens.Path loss model for wireless narrowband communication above flat phantom [J]. In IEE Electronics Letters, 42 (1), Jan.2006.
    96. OOI P CULJAK G, LAWRENCE E. Wireless and Wearable Overview: Stages of Growth Theory in Medical Technology Applications [C]//Proceedings of the Fourth International Conference on Mobile Business (ICMB'05), Sydney, Australia: IEEE Computer Society, 2005: 528-536
    97. LIN Y H, JAN I C KO, CHEN Y Y, et al. A wireless PDA based physiological monitoring system for patient transport [J]. IEEE Transactions on Information Technology in Biomedicine, 2004, 8(4): 439-447.
    98. TIMMONS N F, SCANLON W G. Analysis of the Performance of IEEE 802.15.4 for Medical Sensor Body Area Networking [C]//Proceedings of IEEE International Conference on Sensor and Ad Hoc Communication and Networks (SECON '04), Santa Clara, CA, USA: IEEE press 2004:16-24.
    99. GOLMIE N, CYPHER D, REBALA O. Performance Analysis of low rate wireless technologies for medical applications [J], Elsevier Computer Communications, 2005, 28(10): 1266-1275.
    100. H. Balakrishnan. Opportunities in high-rate wireless sensor networking [online]. 2006 [cited 10 May 2007].
    101. MobiHealth project, http://www.mobihealth.org/
    102. BASUMA project, http://www.basuma.de/.
    103. Wireless connectivity spurs sense and simplicity. Philips Research Password Magazine 2005; 22:20-23.
    104. BALAKRISHNAN H, PADMANABHAN V N, SESHAN S, et al. A comparison of mechanisms for improving TCP performance over wireless links [J]. IEEE/ACM Transactions on Networking, 1997, 5(6): 756-769
    105. SCOTT J, MAPP G. Link layer-based TCP optimization for disconnecting networks [J]. ACM SIGCOMM Computer Communication Review, 2003, 33(5): 31-42.
    106. GANG LU, KRISHNAMACHARI B, RAGHAVENDRA C. Performance Evaluation of the IEEE802.15.4 MAC for Low-Rate Low-Power Wireless Networks[C],//Proceedings of IEEE International Performance Computing and Communications Conference (IPCCC '04), Phoenix, Arizona: IEEE press,2004: 701-706.
    107. JAIN R. A Delay-based approach for Congestion Avoidance in Inter-connected Heterogeneous Networks [J], ACM SIGCOMM Computer Communication Review, 1989, 19(5): 56-71
    108. BIAZ S, VAIDYA N H. Distinguishing Congestion Losses from Wireless Transmission Losses: A Negative Result [C]//Proceedings of the IEEE 7th International Conference on Computer Communications and Networks (IC3N'98), Lafayette, LA, USA: IEEE ComputerSociety, 1998: 390-397.
    109.FU C P, LIEW S C.TCP veno: TCP enhancement for transmission over wireless access networks [J].IEEE Journal on Selected Areas in Communications, 2003, 21(2): 216-228.
    110.BONABEAU E, DORIGO M, THERAULAZ G, Inspiration for optimization from social insect behavior [J].Nature, 2000, 406(6): 39-42.
    111.DORIGO M, BONABEAUE, THERAULAZ G.Ant algorithms and stigmergy [J].Future Generation Computer Systems, 2000, 16(9): 851-871.
    112.LV YONG, ZHAO GUANG-ZHOU, SU FAN-JUN.et al.Adaptive swarm-based routing in communication networks [J].Journal of Zhejiang University: SCIENCE.2004,5(7):867-872.
    113.DORIGO M, DICARO G.Ant colony optimization: a new meta-heuristic [C], //Proceedings of the1999 Congress on Evolutionary Computation, Piscataway: IEEE press,1999:1470-1477.
    114.吴春明,陈治,姜明.蚁群算法中系统初始化及系统参数的研究[J]。电子学报,2006,34(8): 1530-1533.
    115.CUI S, MADANR, GOLDSMITH A J, et al.Energy-delay tradeoff for data collection in TDMA-based sensor networks [C], //Proceedings of ICC2005, Seoul: IEEE press, 2005:3278-3284.
    116.Baran, B., Sosa, R.A New Approach for AntNet Routing[C].//Proc.9th Int.Conf.Computer Communications Networks, 2000;10:303-308.
    117.周洪建.可穿戴式无创血氧饱和度监测仪的设计[J].中国医疗设备.2008, 23(1):21-23.
    118.李建中,李金宝,石胜飞,传感器网络及其数据管理的概念、问题与进展[J].软件学报,2003, 14(10):1717-1727.
    119.孙利民,李建中,陈渝,朱红松,无线传感器网络[J].清华大学出版社,2005.1.
    120.郑增威,吴朝晖,金水祥,无线传感器网络及应用[J].计算机科学,2003, 30(10):138-140.
    121.Najafi N, Ludomirsky A.Initial animal studies of a wireless, batteryless, MEMS implant for cardiovascular applications [J].Biomedical Micro devices 2004; 6(1):61-65.
    122.Emil Jovanov, Aleksandar Milenkovic, Chris Otto, Piet C de Groen.A wireless body area network of intelligent motion sensors for computer assisted physical rehabilitation [J].Journal of NeuroEngineering and Rehabilitation.2005, 2(1):6.
    123.MMA7260A.http://www.freescale.com/files/sensors/doc/data_sheet/MMA7260QT.pdf?pspll=1
    124.MC13213.http://www.freescale.com/files/rf_if/doc/data_sheet/MC1321x.pdf?pspll=1
    125Carlijn V.C., R.Kodde and J.D.Janssen, A triaxial accelerometer and portable data processing unit for the assessment of daily physical activity [J], IEEE Trans.Biomed Eng.1997,44(3):136-147.
    126.M.S.Sun and J.O.Hill.A method for measuring mechanical work and work efficiency during human activities [J].J.Biomech.1993; 26:229-241.
    127.P.M.Mahoudeaux et al,Simple microprocessor-based system for on-line ECG analysis [J],Med.Biol.Eng.Comput.,1981;19:497-500.
    128.A.H.Khandoker, D.Lai and R.K.Begg, et al.A Wavelet-Based Approach for Screening Falls Risk in the Elderly using Support Vector Machines [C].//Proceedings of the 4th ICISIP'06, 2006,15:184-189.
    129.张艳梅.心电信号的处理与自动诊断[硕士论文].2005.江苏:东南大学.2005.
    130.J.L.Cheng, J.R.Jeng, and W.C.Zhe.Heart rate measurement in the presence of Noises [C].//Proceedings of Pervasive health Conference and Workshops 2006, 2006:1-4.
    131.B.Najafi, Aminian, K., Loew, F., Blanc, Y., and Robert, P., Measurement of stand-sit and sit-stand transitions using a miniature gyroscope and its application in fall risk evaluation in the elderly [J].IEEE Transactions on Biomedical Engineering, 2002, 49(8):843-851.
    132.IEEE 802.15.4, Wireless Medium Access Control (MAC) and Physical Layer (PHY) Specifications for Low-Rate Wireless Personal Area Networks (LR-WPAN) [S], New York,NY: IEEE, 2003
    133.马永利,王培勇.运动心率检测系统的研制及心率与肌氧含量同步实验研究[J].北京生物医学工程.2005, 24(4): 299-301.
    134.Saxena S.C.,Kumar V and Hamde S.T..QRS detection using new wavelets[J].Journal of Medical Engineering&Technology, 2002, 26(1): 7-15.
    135.方开泰.实用多元统计分析.上海:华东师范大学出版社,1992.
    136.Frey B, Binder T, Wutte m, et al.HRV and patient outcome in advanced heart failure[J].J Am Coll Cardiol, 1993,21:286A.
    137.Philippe B, michel A, Serge D, et al.Effects of chronic congestive heart failure on 24-hour blood pressure and heart rate patterns[J].Am Heart J.1992,123: 998.
    138.Take Force of Europen Society of Cardiology and the North American Socity of Pacing and Electrophysiology.Heart Rate Variability,Standards of Measurement,Physidogical Interpretation, and Clincal [J].Circulation, 1996;93:1 043-1065.
    139.巴俊强,陈登科..糖尿病心率变异的时域分析[J].贵州医学,2000, 24(10):633-634.
    140.李艳文,姜印平,郑彤,闫宗魁.基于小波变换的脉搏波信号去噪[J].河北工业大学学报.2005; 34(4): 82-85.
    141.黄丹,陈昕,周康源.利用MSP430芯片实现小波变换对涡街信号的去噪测量[J].2004;19(1): 37-40.
    142.潘泉,张磊等,孟晋丽.小波滤波方法及应用.北京:清华大学出版社.2005.

© 2004-2018 中国地质图书馆版权所有 京ICP备05064691号 京公网安备11010802017129号

地址:北京市海淀区学院路29号 邮编:100083

电话:办公室:(+86 10)66554848;文献借阅、咨询服务、科技查新:66554700