植物关联分析应用研究进展
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摘要
随着分子生物学和基因组学的快速发展,关联分析成为近些年来在植物数量性状研究和植物良种选育中行之有效的分析方法。利用关联分析在分子水平阐明植物表型性状的遗传变异规律和机制,从而为植物的农艺性状改良及新品种选育提供新思路。系统详实综述了关联分析基本原理、关联作图的基本策略、关联分析的应用以及各种分子标记在关联分析中的应用,并讨论了关联分析在未来研究中的发展前景。
引文
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[6]Vafaee Y,Ghaderi N,Khadivi A.Morphological variation and marker-fruit trait associations in a collection of grape (Vitis vinifera L.)[J].Scientia Horticulturae,2017,225:771-782.
[7]Gaut B S,Long A D.The lowdown on linkage disequilibrium[J].Plant Cell,2003,15(7):1502-1506.
[8]王荣焕,王天宇,黎裕.关联分析在作物种质资源分子评价中的应用[J].植物遗传资源学报,2007,8(3):366-372.
[9]Single R M,Strayer N,Thomson G,et al.Martin asymmetric linkage disequilibrium:tools for assessing multiallelic LD[J].Human Immunology,2016,77(3):288-294.
[10]谭贤杰,吴子恺,程伟东,等.关联分析及其在植物遗传学研究中的应用[J].植物学报,2011,46(1):108-118.
[11]丁霞,王林海,张艳欣,等.芝麻核心种质株高构成相关性状的遗传变异及关联定位[J].中国油料作物学报,2013,35(3):262-270.
[12]蒋思霞,倪正斌,印志同,等.糯玉米自交系遗传多样性及其产量、农艺性状与SSR分子标记的关联研究[J].安徽农业科学,2012,40(6):3212-3217,3283.
[13]王彩洁,徐冉,于明飞.关联分析在植物育种中的应用现状[J].山东农业科学,2012,44(6):32-38,62.
[14]Gupta P K,Rustgi S,Kulwal P L.Linkage disequilibrium and association in higher plants:present status and future prospects[J].Plant Mol Biol,2005,57:461-485.
[15]Oraguzie N C,Wilcox P L,Rikkerink E H A,et al.Linkage disequilibrium[M]// Oraguzie N C,Rikkerink E H A,Gardiner S E,et al.Association mapping in Plants.New York:Springer Verlag,2007:11-39.
[16]杨小红,严建兵,郑艳萍,等.植物数量性状关联分析研究进展[J].作物学报,2007,33(4):523-530.
[17]倪正斌.糯玉米自交系遗传多样性及产量,农艺性状与SSR分子标记的关联研究[D].扬州:扬州大学,2010.
[18]Doerge R W.Mapping and analysis of quantitative trait loci in experimental populations[J].Nat Rev Genet,2002,3:43-52.
[19]Holland J B.Genetic architecture of complex traits in plants[J].Curr Opin Plant Biol,2007,10:156-161.
[20]鲁清.水稻种质资源重要农艺性状的全基因组关联分析[D].北京:中国农业科学院,2016.
[21]代力强,吴律,董青松,等.玉米籽粒长度的全基因组关联分析[J].西北农林科技大学学报(自然科学版),2018,46(6):1-8.
[22]刘静.小麦株高性状的全基因组关联分析[C].第八届全国小麦基因组学及分子育种大会摘要集,2017:1.
[23]Feng L,Chen B Y,Xu K,et al.A genome-wide association study of plant height and primary branch number in rapeseed(Brassica napus)[J].Plant Science,2016,242:169-177.
[24]李海权,刁现民.关联分析及其在植物研究中的应用[J].河北农业科学,2010,14(11):157-160.
[25]于海霞,肖静,田纪春,等.关联分析及其在植物中的应用[J].基因组学与应用生物学,2009,28(1):187-194.
[26]霍冬敖.玉米穗粒数相关性状QTL定位与候选基因关联分析[D].武汉:华中农业大学,2016.
[27]Thornsberry J M,Goodman M M,Doebley J,et al.Dwarf8 polymorphisms associate with variation in flowering time[J].Nature Genetics,2001,28(3):286-289.
[28]Fujioka S,Yamane H,Spray C R,et al.The dominant non-gibberellin-responding dwarf mutant (D8) of maize accumulates native gibberellins[J].Proceedings of the National Academy of Sciences of the United States of America,1988,85(23):9031-9035.
[29]Yu X,Bai G H,Luo N,et al.Association of simple sequence repeat (SSR) markers with submergence tolerance in diverse populations of perennial ryegrass[J].Plant Science,2011,180(2):391-398.
[30]Perez M B,Zhao J,Yin Y H,et al.Association mapping of brassinosteroid candidate genes and plant architecture in a diverse panel of Sorghum bicolor[J].Theoretical and Applied Genetics,2014,127(12):2645-2662.
[31]于永涛.玉米核心自交系群体结构及耐旱相关候选基因rab17的等位基因多样性分析[D].北京:中国农业科学院研究生院,2006.
[32]Andersen J R,Zein I,Wenzel G,et al.High levels of linkage disequilibrium and associations with forage quality at a phenylalanine ammonia-lyase locus in European maize (Zea mays L.) inbreds[J].Theoretical and Applied Genetics,2007,114(2):307-319.
[33]刘翠霞.葡萄果实单萜化合物含量的QTL定位及其合成调控的候选基因筛选[D].武汉:中国科学院武汉植物园,2017.
[34]段继凤.甘蓝型油菜含油量性状全基因组关联分析[D].武汉:华中农业大学,2013.
[35]Lander E,Kruglyak L.Genetic dissection of complex traits:guidelines for interpreting and reporting linkage results[J].Nat Genet,1995,11:241-247.
[36]Pritchard J K,Rosenberg N A .Use of unlinked genetic markers to detect population stratification in association studies[J].Am J Hum Genet,1999,65:220-228.
[37]Yu J M,Pressoir G,Briggs W H,et al.A unified mixedmodel method for association mapping that accounts for multiple levels of relatedness[J].Nat Genet,2006,38:203-208.
[38]Spielman R S,McGinnis R E,Ewens W J.Transmission test for linkage disequilibrium:the insulin gene region and insulin-dependent diabetes mellitus (IDDM)[J].American Journal of Human Genetics,1993,52(3):506-516.
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