12种清热解毒类药食两用植物研究进展
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摘要
根据我国卫生健康委员会公布的《既是食品又是药品的中药名单》,结合临床用药及民间常见用于清解热毒的偏方,选出12种具有开发价值的清热解毒类药食两用植物。此类植物具有清热解毒、抗氧化、抗毒、抗菌消炎、保护肝脏、增强免疫等多方面的药理功能,在食品、保健品和美容化妆品方面有广泛运用,是一类具有巨大发展前景的药食两用植物。通过综述这12种药食两用植物的清热解毒功效和药理研究,概括其在食品、保健品和美容化妆品等方面的运用,为其发展提供依据。
According to the list of Chinese medicines that are both food and medicines published by the National Health Commission of the People's Republic of China,combined with clinical medicines and folk remedies commonly used to clear heat and poison,12 kinds of heat-clearing and detoxifying medicines and food plants with development values were selected. These plants had many pharmacological functions such as heat-clearing and detoxifying,anti-oxidation,anti-toxicity,anti-bacterial and anti-inflammatory,protecting the liver,and enhancing immunity. They were a kind of medicine and food plant with great development prospects and were widely used in food,health products and cosmetics. By reviewing the heat-clearing and detoxifying effects and pharmacological studies of these 12 kinds of medicines and food plants,their applications in food,health products and cosmetics can be summarized to provide a basis for their development.
According to the list of Chinese medicines that are both food and medicines published by the National Health Commission of the People's Republic of China,combined with clinical medicines and folk remedies commonly used to clear heat and poison,12 kinds of heat-clearing and detoxifying medicines and food plants with development values were selected. These plants had many pharmacological functions such as heat-clearing and detoxifying,anti-oxidation,anti-toxicity,anti-bacterial and anti-inflammatory,protecting the liver,and enhancing immunity. They were a kind of medicine and food plant with great development prospects and were widely used in food,health products and cosmetics. By reviewing the heat-clearing and detoxifying effects and pharmacological studies of these 12 kinds of medicines and food plants,their applications in food,health products and cosmetics can be summarized to provide a basis for their development.
引文
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[2]王创畅,吴伟,陈浩,等.急性心肌梗死热毒证候病因探讨回顾性分析[J].中国实验方剂学杂志,2017,23(11):158-164.
[3]柏正平,孙春林,卜献春,等.心可舒胶囊治疗热毒血瘀证冠心病心绞痛60例疗效观察[J].中国中医药科技,2011,18(1):60.
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[6]赵海滨,郭玉海,左俊岭,等.中风病之内生热毒形成演变及特性初探[J].上海中医药杂志,2003,37(12):33-35.
[7]周庆博,骆丰.中风热毒论[J].山东中医药大学学报,2000,24(3):176-178.
[8]冯津津.马齿苋的化学成分及药理作用研究进展[J].云南中医中药杂志,2013,34(7):66-68.
[9]于立恒.蒲公英药理作用研究进展[J].实用中医药杂志,2012,28(7):617-620.
[10]顾静蓉,冯莉莉,罗建伟,等.鱼腥草的药理作用及临床应用新进展[J].海峡药学,2006,18(3):121-123.
[11]陈蔚燕.紫花地丁不同方式提取物抑菌效果研究[J].现代农药,2014,13(5):38-40.
[12]尹华东,朱庆,赵小玲,等.一种放养鸡专用饲料配方:CN105285479A[P].2016-02-03.
[13]ZHANG X J,JI Y B,QU Z Y,et al.Experimental studies on antibiotic functions of Portulaca oleracea L.in vitro[J].Chinese Juornal of Microecology,2002,14(5):277-280.
[14]朱丹,牛广财,孙希云,等.马齿苋黄酮类物质抑菌作用的研究[J].安徽农业科学,2006,34(1):7-8.
[15]库尔班·吾斯曼,穆赫塔尔·伊米尔艾山,帕提古丽·伊米尔艾山.马齿苋子中多糖的提取分离及抑菌活性研究[J].食品研究与开发,2009,30(7):28-30.
[16]AI-BISHRI W M,ABDEL-REHEIM E S,ZAKI A R.Purslane protects against the reproductive toxicity of carbamazepine treatment in pilocarpine-induced epilepsy model[J].Asian Pacific Journal of Tropical Biomedicine,2017,7(4):339-346.
[17]屠国昌.蒲公英化学成分、药理作用和临床应用[J].海峡药学,2012,24(5):33-35.
[18]王亚茹,李雅萌,杨娜,等.蒲公英属植物的化学成分和药理作用研究进展[J].特产研究,2017,39(4):67-75.
[19]黄飞.蒲公英在兽医临床上的应用研究[J].农民致富之友,2018(8):232.
[20]陈清赔,杨辉.鱼腥草不同部位挥发油组分与抗菌活性分析[J].临床合理用药杂志,2018,11(11B):112-114.
[21]曾慧芳,曾艳芳.鱼腥草注射液超声雾化治疗慢性咽炎的临床疗效观察[J].吉林医学,2016,37(3):550-551.
[22]张俭,刘胜贵,伍贤进,等.鱼腥草在畜禽疾病防治中的应用[J].江苏农业科学,2006(6):325-327.
[23]谢雪林,李兴如.鱼腥草在兽医临床上的应用[J].中兽医学杂志,2016(3):59-59.
[24]KIM J M,HWANG I H,JANG I S,et al.Houttuynia cordata thunb promotes activation of HIF-1A-FOXO3 and MEF2A pathways to induce apoptosis in human HepG2hepatocellular carcinoma cells[J].Integrative Cancer Therapies,2016,16(3):360-372.
[25]杨亚军,周秋贵,曾红,等.车前草化学成分及新生物活性研究进展[J].中成药,2011,33(10):1771-1776.
[26]陶玉杰.车前子不同炮制品治疗慢性功能性便秘的临床疗效对比观察[J].中国实用医药,2017,12(31):127-128.
[27]李志鹏,李霞,苏云,等.车前子黄芪颗粒剂治疗肛肠病术后尿潴留的临床研究[J].中国民间疗法,2017,25(2):38-39.
[28]吕昂,范新,苏倩,等.车前草醇提物治疗肾草酸钙结石的作用及其机制[J].中国临床药理学与治疗学,2016,21(11):1239-1245.
[29]李永生,何希瑞,杨燕,等.紫花地丁化学成分与药理活性研究新进展[J].环球中医药,2013,6(4):313-318.
[30]陈胡兰,汤沛然,陈兴,等.紫花地丁抗炎及体外抑菌作用活性部位的筛选研究[J].成都中医药大学学报,2008,31(2):52-53.
[31]谢占芳.八种菊花挥发性成分及其抑菌活性研究[D].开封:河南大学,2016.
[32]钟晓凤.金银花药用成分及现代临床药理分析[J].光明中医,2016,31(6):887-888.
[33]王亚琼,陈卫,钟水生,等.金银花清热解毒作用的血清代谢组学研究[J].中药材,2016,39(5):1129-1133.
[34]雷志钧,周日宝,曾嵘,等.灰毡毛忍冬与正品金银花解热作用的比较研究[J].湖南中医学院学报,2005,25(5):16-17.
[35]贾佼佼,李艳,苗明三.紫苏的化学、药理及应用[J].中医学报,2016,31(9):1354-1356.
[36]房海灵,李维林,任冰如,等.薄荷属植物的化学成分及药理学研究进展[J].中国药业,2010,19(10):13-17.
[37]李岗,余德顺,杨军,等.超临界CO2萃取薄荷挥发油及其抗氧化能力的研究[J].食品科技,2013,38(1):276-279.
[38]王红涛.薄荷挥发油的提取与应用研究[J].吉林农业,2012(11):54.
[39]谢宗万.古今药用连翘品种的延续与变迁[J].中医药研究,1992(3):37-39.
[40]苏杰,李娜,惠伯棣,等.鱼腥草作为保健食品原料潜力的概述[J].食品工业科技,2017,38(6):349-354.
[41]胡晖,冷桂华.车前草保健含片的研制[J].安徽农业科学,2010,38(20):11033-11035.
[42]董伟,于天浩,周敬.紫花地丁提取物在化妆品中的应用[C]//第十届中国化妆品学术研讨会论文集.北京:中国香料香精化妆品工业协会,2014.
[43]杨子佳,祝钧.金银花的功效成分及其在化妆品中的应用[J].日用化学品科学,2013,36(11):28-31,41.
[2]王创畅,吴伟,陈浩,等.急性心肌梗死热毒证候病因探讨回顾性分析[J].中国实验方剂学杂志,2017,23(11):158-164.
[3]柏正平,孙春林,卜献春,等.心可舒胶囊治疗热毒血瘀证冠心病心绞痛60例疗效观察[J].中国中医药科技,2011,18(1):60.
[4]彭敏.热毒与血栓形成关系的实验及临床研究[D].济南:山东中医药大学,2008.
[5]梁爱华,陈明伟.热毒与血栓性疾病的临床相关性分析与探讨[J].中国中药杂志,2008,33(4):476-481.
[6]赵海滨,郭玉海,左俊岭,等.中风病之内生热毒形成演变及特性初探[J].上海中医药杂志,2003,37(12):33-35.
[7]周庆博,骆丰.中风热毒论[J].山东中医药大学学报,2000,24(3):176-178.
[8]冯津津.马齿苋的化学成分及药理作用研究进展[J].云南中医中药杂志,2013,34(7):66-68.
[9]于立恒.蒲公英药理作用研究进展[J].实用中医药杂志,2012,28(7):617-620.
[10]顾静蓉,冯莉莉,罗建伟,等.鱼腥草的药理作用及临床应用新进展[J].海峡药学,2006,18(3):121-123.
[11]陈蔚燕.紫花地丁不同方式提取物抑菌效果研究[J].现代农药,2014,13(5):38-40.
[12]尹华东,朱庆,赵小玲,等.一种放养鸡专用饲料配方:CN105285479A[P].2016-02-03.
[13]ZHANG X J,JI Y B,QU Z Y,et al.Experimental studies on antibiotic functions of Portulaca oleracea L.in vitro[J].Chinese Juornal of Microecology,2002,14(5):277-280.
[14]朱丹,牛广财,孙希云,等.马齿苋黄酮类物质抑菌作用的研究[J].安徽农业科学,2006,34(1):7-8.
[15]库尔班·吾斯曼,穆赫塔尔·伊米尔艾山,帕提古丽·伊米尔艾山.马齿苋子中多糖的提取分离及抑菌活性研究[J].食品研究与开发,2009,30(7):28-30.
[16]AI-BISHRI W M,ABDEL-REHEIM E S,ZAKI A R.Purslane protects against the reproductive toxicity of carbamazepine treatment in pilocarpine-induced epilepsy model[J].Asian Pacific Journal of Tropical Biomedicine,2017,7(4):339-346.
[17]屠国昌.蒲公英化学成分、药理作用和临床应用[J].海峡药学,2012,24(5):33-35.
[18]王亚茹,李雅萌,杨娜,等.蒲公英属植物的化学成分和药理作用研究进展[J].特产研究,2017,39(4):67-75.
[19]黄飞.蒲公英在兽医临床上的应用研究[J].农民致富之友,2018(8):232.
[20]陈清赔,杨辉.鱼腥草不同部位挥发油组分与抗菌活性分析[J].临床合理用药杂志,2018,11(11B):112-114.
[21]曾慧芳,曾艳芳.鱼腥草注射液超声雾化治疗慢性咽炎的临床疗效观察[J].吉林医学,2016,37(3):550-551.
[22]张俭,刘胜贵,伍贤进,等.鱼腥草在畜禽疾病防治中的应用[J].江苏农业科学,2006(6):325-327.
[23]谢雪林,李兴如.鱼腥草在兽医临床上的应用[J].中兽医学杂志,2016(3):59-59.
[24]KIM J M,HWANG I H,JANG I S,et al.Houttuynia cordata thunb promotes activation of HIF-1A-FOXO3 and MEF2A pathways to induce apoptosis in human HepG2hepatocellular carcinoma cells[J].Integrative Cancer Therapies,2016,16(3):360-372.
[25]杨亚军,周秋贵,曾红,等.车前草化学成分及新生物活性研究进展[J].中成药,2011,33(10):1771-1776.
[26]陶玉杰.车前子不同炮制品治疗慢性功能性便秘的临床疗效对比观察[J].中国实用医药,2017,12(31):127-128.
[27]李志鹏,李霞,苏云,等.车前子黄芪颗粒剂治疗肛肠病术后尿潴留的临床研究[J].中国民间疗法,2017,25(2):38-39.
[28]吕昂,范新,苏倩,等.车前草醇提物治疗肾草酸钙结石的作用及其机制[J].中国临床药理学与治疗学,2016,21(11):1239-1245.
[29]李永生,何希瑞,杨燕,等.紫花地丁化学成分与药理活性研究新进展[J].环球中医药,2013,6(4):313-318.
[30]陈胡兰,汤沛然,陈兴,等.紫花地丁抗炎及体外抑菌作用活性部位的筛选研究[J].成都中医药大学学报,2008,31(2):52-53.
[31]谢占芳.八种菊花挥发性成分及其抑菌活性研究[D].开封:河南大学,2016.
[32]钟晓凤.金银花药用成分及现代临床药理分析[J].光明中医,2016,31(6):887-888.
[33]王亚琼,陈卫,钟水生,等.金银花清热解毒作用的血清代谢组学研究[J].中药材,2016,39(5):1129-1133.
[34]雷志钧,周日宝,曾嵘,等.灰毡毛忍冬与正品金银花解热作用的比较研究[J].湖南中医学院学报,2005,25(5):16-17.
[35]贾佼佼,李艳,苗明三.紫苏的化学、药理及应用[J].中医学报,2016,31(9):1354-1356.
[36]房海灵,李维林,任冰如,等.薄荷属植物的化学成分及药理学研究进展[J].中国药业,2010,19(10):13-17.
[37]李岗,余德顺,杨军,等.超临界CO2萃取薄荷挥发油及其抗氧化能力的研究[J].食品科技,2013,38(1):276-279.
[38]王红涛.薄荷挥发油的提取与应用研究[J].吉林农业,2012(11):54.
[39]谢宗万.古今药用连翘品种的延续与变迁[J].中医药研究,1992(3):37-39.
[40]苏杰,李娜,惠伯棣,等.鱼腥草作为保健食品原料潜力的概述[J].食品工业科技,2017,38(6):349-354.
[41]胡晖,冷桂华.车前草保健含片的研制[J].安徽农业科学,2010,38(20):11033-11035.
[42]董伟,于天浩,周敬.紫花地丁提取物在化妆品中的应用[C]//第十届中国化妆品学术研讨会论文集.北京:中国香料香精化妆品工业协会,2014.
[43]杨子佳,祝钧.金银花的功效成分及其在化妆品中的应用[J].日用化学品科学,2013,36(11):28-31,41.
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