Kigoma-Mpanda region is located in the west Tanzania with Precambrian rocks spreading widely. In recent years a group of new isotopic age data has been obtained from the region. The upper cross point age of tonalite sample form Shanwe hill is 2.64 Ga indicating that the granite body is formed in Neo-archean Era. However, the lower cross point age is 0.7 Ga that may represent its metamorphic age or the age of inheriting zircon. Age of granite from Filimult hill is determined at (1.893±3) Ma suggesting that it is the product of Ubendian Period. Age of Gua granite is (1.889±40) Ma showing that it is the product of syn-tectonic period of Filimult hill granite. Age of (1.337±47) Ma for Nyanahanga dolerite represents the time when Neo-Proterozoic basic dykes intruded.