In this paper, the authors investigated the geologic conditions and metallogenic rules and established a porphyry copper deposit metallogenic model for eastern Gangdise in Tibet. And then the indexes of metallogenic prognosis are summarized. Using the characteristic analysis method of mineral resource assessment system (MRAS) based on the geographic information system (GIS), the metallogenic prospect has been predicted for porphyry copper polymetallic deposits. The result also shows that the delimitaed area of metallogenic prognosis includes mostly known large and medium-sized copper deposits and is in accordance well with the geological analysis. The result shows that there stil1 exists a great potential of porphyry copper deposits in the eastern section of Gangdise.