Highly Efficient Ultrasonic-Assisted CuCl-Catalyzed 1,3-Dipolar Cycloaddition Reactions in Water: Synthesis of Coumarin Derivatives Linked with 1,2,3-Triazole Moiety

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• 作者：Xu Li ; Xiaolan Chen ; Yuqin Jiang ; Senshen Chen ; Lingbo Qu ; Zhibo Qu ; Jinwei Yuan and Hanyu Shi
• 刊名：Journal of Heterocyclic Chemistry
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：53
• 期：5
• 页码：1402-1411
• 全文大小：4094K
• ISSN：1943-5193

文摘

By introducing ultrasound irradiation into “on water” CuCl-catalyzed 1,3-dipolar Huisgen cycloaddition, the reaction efficiencies were notably promoted toward a wide variety of applicable azides and alkynes at room temperature, and a series of coumarin derivatives linked with 1,2,3-triazole moiety were synthesized using the optimized conditions.